Programme 1 aims to understand:
Our aims are to:
Aim: To elucidate the risk factors for, and mechanisms which underlie, the developmental origins of osteoporosis and other musculoskeletal disorders; and to develop intervention studies aimed at modifying later disease risk through nutritional and other interventions targeted at critical periods of early development.
To utilise integrative biology approaches to data from observational and intervention studies to develop biomarkers, therapeutics and nutrition/lifestyle interventions to improve reproductive health, child growth, adiposity and development, and promote healthy ageing and treat sarcopenia (linking with Programmes 1 and 3), thereby enhancing human capital and reducing cardiometabolic risks arising in early life and their impact on later disease.
Objective: The overall strategic objective for this programme is to improve cardiometabolic health across the lifecourse by addressing the developmental determinants of disease that arise before conception and during pregnancy. The programme takes a behavioural systems approach to improving health across the lifecourse with an emphasis on preconception and pregnancy.
We are keen to maximise the use of data from our cohorts, trials and other studies, and welcome approaches from researchers to explore use of the data. We have a procedure for data sharing to ensure that we preserve the confidentiality of the data and we need to abide by the terms of participant consent for each study. Our model for data sharing is a collaborative one and we work with researchers using the data to support them in the interpretation of the various data variables and of their findings. If you are interested in using our data, please email the Unit on firstname.lastname@example.org