Overview: This cohort comprises 329 babies born to women with pre-eclampsia and 646 born to normotensive women in one Pune hospital during 2006-2010. Maternal plasma fatty acids, growth factors, 1-Carbon nutrients/metabolites, and oxidative stress markers were measured as well as cord blood fatty acids and brain-derived growth factor.
Objective: To compare body composition, cardiometabolic risk factors and cognitive function between children of mothers who did and did not develop pre-eclampsia, and to test hypotheses relating maternal fatty acid and 1-Carbon nutrient metabolism to these outcomes in the children.
Methods: In the next quinquennium, the children will be followed up at 5-6 years of age to measure cardiometabolic risk factors and cognitive function.
Research outputs in the last quinquennium: None. This is a new collaboration.