Overview: This cohort comprises 477 children born in the KEM Hospital, for whom birthweight was available from obstetric records. They had cardiometabolic risk factors measured at 8 years of age, and have recently been re-studied at 21 years. It is one of few cohorts that has blood measurements of cardiometabolic risk factors in childhood and young adult life. There are no plans to re-study this cohort in the next 5 years.

Key findings in the last quinquennium:

  • There was significant tracking of risk markers from 8 to 21 years, strongest for cholesterol, and weakest for glucose and insulin977
  • Insulin resistance (HOMA) at 8 years was positively related to all cardiometabolic risk markers at 21 years, independent of adiposity [manuscript under review]