• 2017

    1) Armbrecht, G., Felsenberg, D., Ganswindt, M., Lunt, M., Kaptoge, S. K., Abendroth, K., et al. (2017). “Degenerative inter-vertebral disc disease osteochondrosis intervertebralis in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over.” Rheumatology 07: 07.

    2) Barker, M., D’Angelo, S., Ntani, G., Lawrence, W., Baird, J., Jarman, M., et al. (2017). “The relationship between maternal self-efficacy, compliance and outcome in a trial of vitamin D supplementation in pregnancy.” Osteoporosis International 28(1): 77-84.

    3) Bayliss, L. E., Culliford, D., Monk, A. P., Glyn-Jones, S., Prieto-Alhambra, D., Judge, A., et al. (2017). “The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.” The Lancet 389(10077): 1424-1430.

    4) Beaudart, C., Dawson, A., Shaw, S. C., Harvey, N. C., Kanis, J. A., Binkley, N., et al. (2017). “Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review.” Osteoporosis International 28(6): 1817-1833.

    5) Beaudart, C., Edwards, M., Moss, C., Reginster, J. Y., Moon, R., Parsons, C., et al. (2017). “English translation and validation of the SarQoL, a quality of life questionnaire specific for sarcopenia.” Age and Ageing 46(2): 271-277.

    6) Bishop, F. L., Yardley, L., Cooper, C., Little, P. and Lewith, G. (2017). “Predicting adherence to acupuncture appointments for low back pain: A prospective observational study.” BMC Complementary and Alternative Medicine 17(1).

    7) Bloom, I., Edwards, M., Jameson, K. A., Syddall, H. E., Dennison, E., Gale, C. R., et al. (2017). “Influences on diet quality in older age: The importance of social factors.” Age and Ageing 46(2): 277-283.

    8) Coutts, L. V., Jenkins, T., Oreffo, R. O. C., Dunlop, D. G., Cooper, C., Harvey, N. C., et al. (2017). “Local Variation in Femoral Neck Cortical Bone: In Vitro Measured Bone Mineral Density, Geometry and Mechanical Properties.” Journal of Clinical Densitometry 20(2): 205-215.

    9) Curtis, E. M., Murray, R., Titcombe, P., Cook, E., Clarke-Harris, R., Costello, P., et al. (2017). “Perinatal DNA Methylation at CDKN2A Is Associated With Offspring Bone Mass: Findings From the Southampton Women’s Survey.” Journal of Bone and Mineral Research.

    10) Edwards, M. H., Paccou, J., Ward, K. A., Jameson, K. A., Moss, C., Woolston, J., et al. (2017). “The relationship of bone properties using high resolution peripheral quantitative computed tomography to radiographic components of hip osteoarthritis.” Osteoarthritis and Cartilage Date of Publication.

    11) El-Heis, S., Crozier, S. R., Healy, E., Robinson, S. M., Harvey, N. C., Cooper, C., et al. (2017). “Maternal stress and psychological distress preconception: association with offspring atopic eczema at age 12 months.” Clinical and Experimental Allergy 47(6): 760-769.

    12) Gale, C. R., Mottus, R., Deary, I. J., Cooper, C. and Sayer, A. A. (2017). “Personality and Risk of Frailty: the English Longitudinal Study of Ageing.” Annals of Behavioral Medicine 51(1): 128-136.

    13) Gale, C. R., Ritchie, S. J., Cooper, C., Starr, J. M. and Deary, I. J. (2017). “Cognitive Ability in Late Life and Onset of Physical Frailty: The Lothian Birth Cohort 1936.” Journal of the American Geriatrics Society 65(6): 1289-1295.

    14) Hadji, P., Aapro, M. S., Body, J. J., Gnant, M., Brandi, M. L., Reginster, J. Y., et al. (2017). “Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG.” Journal of Bone Oncology 7(pp 1-12).

    15) Handel, M. N., Frederiksen, P., Cohen, A., Cooper, C., Heitmann, B. L. and Abrahamsen, B. (2017). “Neonatal vitamin D status from archived dried blood spots and future risk of fractures in childhood: results from the D-tect study, a population-based case-cohort study.” American Journal of Clinical Nutrition 17: 17.

    16) Handel, M. N., Frederiksen, P., Osmond, C., Cooper, C., Abrahamsen, B. and Heitmann, B. L. (2017). “Prenatal exposure to Vitamin D from fortified margarine and risk of fractures in late childhood: Period and cohort results from 222 000 subjects in the D-tect observational study.” British Journal of Nutrition 117(6): 872-881.

    17) Hannam, K., Deere, K. C., Hartley, A., Clark, E. M., Coulson, J., Ireland, A., et al. (2017). “A novel accelerometer-based method to describe day-to-day exposure to potentially osteogenic vertical impacts in older adults: findings from a multi-cohort study.” Osteoporosis International 28(3): 1001-1011.

    18) Hiligsmann, M., Dellaert, B. G., Dirksen, C. D., Watson, V., Bours, S., Goemaere, S., et al. (2017). “Patients’ preferences for anti-osteoporosis drug treatment: a cross-European discrete choice experiment.” Rheumatology 06: 06.

    19) Hollis, J. L., Crozier, S. R., Inskip, H. M., Cooper, C., Godfrey, K. M., Harvey, N. C., et al. (2017). “Modifiable risk factors of maternal postpartum weight retention: an analysis of their combined impact and potential opportunities for prevention.” International Journal of Obesity 25: 25.

    20) Jackson, K. A., Sanchez-Santos, M. T., MacKinnon, A. L., Turner, A., Kuznik, K., Ellis, S., et al. (2017). “Bone density and body composition in newly licenced professional jockeys.” Osteoporosis International.

    21) Klop, C., van Staa, T. P., Cooper, C., Harvey, N. C. and de Vries, F. (2017). “The epidemiology of mortality after fracture in England: variation by age, sex, time, geographic location, and ethnicity.” Osteoporosis International 28(1): 161-168.

    22) Leal, J., Gray, A. M., Hawley, S., Prieto-Alhambra, D., Delmestri, A., Arden, N. K., et al. (2017). “Cost-Effectiveness of Orthogeriatric and Fracture Liaison Service Models of Care for Hip Fracture Patients: A Population-Based Study.” Journal of Bone and Mineral Research 32(2): 203-211.

    23) Lillycrop, K., Murray, R., Cheong, C., Teh, A. L., Clarke-Harris, R., Barton, S., et al. (2017). “ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity.” EBioMedicine 19(pp 60-72).

    24) Lu, R. S., Dennison, E., Denison, H., Cooper, C., Taylor, M. and Bottema, M. J. (2017). “Texture analysis based on Gabor filters improves the estimate of bone fracture risk from DXA images.” Comput Methods Biomech Biomed Eng Imaging Vis.

    25) Lucas, R., Martins, A., Severo, M., Silva, P., Monjardino, T., Gaio, A. R., et al. (2017). “Quantitative modelling of hip fracture trends in 14 European countries: testing variations of a shared reversal over time.” Scientific Reports 7(1): 3754.

    26) Mikkola, T. M., von Bonsdorff, M. B., Osmond, C., Salonen, M. K., Kajantie, E., Cooper, C., et al. (2017). “Childhood growth predicts higher bone mass and greater bone area in early old age: findings among a subgroup of women from the Helsinki Birth Cohort Study.” Osteoporosis International.

    27) Moon, R. J., Curtis, E. M., Davies, J. H., Cooper, C. and Harvey, N. C. (2017). “Seasonal variation in Internet searches for vitamin D.” Archives of Osteoporosis 12(1).

    28) Moon, R. J., Harvey, N. C., Cooper, C., D’Angelo, S., Curtis, E. M., Crozier, S. R., et al. (2017). “Response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants.” Journal of Clinical Endocrinology & Metabolism 29: 29.

    29) Palmer, K. T., D’Angelo, S., Harris, E. C., Linaker, C., Gale, C. R., Evandrou, M., et al. (2017). “Frailty, prefrailty and employment outcomes in Health and Employment After Fifty (HEAF) Study.” Occupational & Environmental Medicine 74(7): 476-482.

    30) Palmer, K. T., D’Angelo, S., Harris, E. C., Linaker, C., Sayer, A. A., Gale, C. R., et al. (2017). “Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study.” Scandinavian Journal of Work, Environment & Health 43(2): 136-145.

    31) Roberts, H. C., Pilgrim, A. L., Jameson, K. A., Cooper, C., Sayer, A. A. and Robinson, S. (2017). “The Impact of Trained Volunteer Mealtime Assistants on the Dietary Intake of Older Female In-Patients: The Southampton Mealtime Assistance Study.” Journal of Nutrition, Health & Aging 21(3): 320-328.

    32) Robinson, S. M., Jameson, K. A., Bloom, I., Ntani, G., Crozier, S. R., Syddall, H., et al. (2017). “Development of a Short Questionnaire to Assess Diet Quality among Older Community-Dwelling Adults.” Journal of Nutrition, Health & Aging 21(3): 247-253.

    33) Rosengren, B. E., Bjork, J., Cooper, C. and Abrahamsen, B. (2017). “Recent hip fracture trends in Sweden and Denmark with age-period-cohort effects.” Osteoporosis International 28(1): 139-149.

    34) Saengnipanthkul, S., Waikakul, S., Rojanasthien, S., Totemchokchyakarn, K., Srinkapaibulaya, A., Cheh Chin, T., et al. (2017). “Differentiation of patented crystalline glucosamine sulfate from other glucosamine preparations will optimize osteoarthritis treatment.” International Journal of Rheumatic Diseases 23: 23.

    35) Shah, A., Prieto-Alhambra, D., Hawley, S., Delmestri, A., Lippett, J., Cooper, C., et al. (2017). “Geographic variation in secondary fracture prevention after a hip fracture during 1999-2013: a UK study.” Osteoporosis International 28(1): 169-178.

    36) Syddall, H. E., Westbury, L. D., Dodds, R., Dennison, E., Cooper, C. and Sayer, A. A. (2017). “Mortality in the Hertfordshire Ageing Study: Association with level and loss of hand grip strength in later life.” Age and Ageing 46(3): 407-412.

    37) Timmermans, E. J., van der Pas, S., Schaap, L. A., Cooper, C., Edwards, M. H., Gale, C. R., et al. (2017). “Associations between perceived neighbourhood problems and quality of life in older adults with and without osteoarthritis: Results from the Hertfordshire Cohort Study.” Health & Place 43: 144-150.

    38) van der Velde, R. Y., Wyers, C. E., Teesselink, E., Geusens, P. P., van den Bergh, J. P., de Vries, F., et al. (2017). “Trends in oral anti-osteoporosis drug prescription in the United Kingdom between 1990 and 2012: Variation by age, sex, geographic location and ethnicity.” Bone 94: 50-55.

    39) Veronese, N., Stubbs, B., Crepaldi, G., Solmi, M., Cooper, C., Harvey, N. C. W., et al. (2017). “Relationship Between Low Bone Mineral Density and Fractures With Incident Cardiovascular Disease: A Systematic Review and Meta-Analysis.” Journal of Bone and Mineral Research 32(5): 1126-1135.

    40) Veronese, N., Stubbs, B., Solmi, M., Smith, T. O., Noale, M., Cooper, C., et al. (2017). “Association between lower limb osteoarthritis and incidence of depressive symptoms: Data from the osteoarthritis initiative.” Age and Ageing 46(3): 470-476.

    41) Warner, S. C., Walsh, D. A., Laslett, L. L., Maciewicz, R. A., Soni, A., Hart, D. J., et al. (2017). “Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.” European Journal of Pain.

    42) Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Cowan, M. J., Paciorek, C. J., et al. (2017). “Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants.” The Lancet 389(10064): 37-55.

    2016

    1) Arden, N. K., Cro, S., Sheard, S., Dore, C. J., Bara, A., Tebbs, S. A., et al. (2016). “The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial.” Osteoarthritis & Cartilage 24(11): 1858-1866.

    2) Azagra, R., Zwart, M., Aguye, A., Martin-Sanchez, J. C., Casado, E., Diaz-Herrera, M. A., et al. (2016). “Fracture experience among participants from the FROCAT study: what thresholding is appropriate using the FRAX tool?” Maturitas 83: 65-71.

    3) Baczynska, A. M., Shaw, S., Roberts, H. C., Cooper, C., Aihie Sayer, A. and Patel, H. P. (2016). “Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome.” Journal of Visualized Experiments(109): e53075.

    4) Baird, J., Barker, M., Harvey, N. C., Lawrence, W., Vogel, C., Jarman, M., et al. (2016). “Southampton PRegnancy Intervention for the Next Generation (SPRING): protocol for a randomised controlled trial.” Trials [Electronic Resource] 17(1): 493.

    5) Baird, J., Hill, C. M., Harvey, N. C., Crozier, S., Robinson, S. M., Godfrey, K. M., et al. (2016). “Duration of sleep at 3 years of age is associated with fat and fat-free mass at 4 years of age: the Southampton Women’s Survey.” Journal of Sleep Research 25(4): 412-418.

    6) Barker, M., Baird, J., Lawrence, W., Vogel, C., Strommer, S., Rose, T., et al. (2016). “Preconception and pregnancy: opportunities to intervene to improve women’s diets and lifestyles.” Journal of Developmental Origins of Health and Disease: 1-4.

    7) Barton, S. J., Mosquera, M., Cleal, J. K., Fuller, A. S., Crozier, S. R., Cooper, C., et al. (2016). “Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women’s survey.” Placenta 38: 100-106.

    8) Beaudart, C., McCloskey, E., Bruyere, O., Cesari, M., Rolland, Y., Rizzoli, R., et al. (2016). “Sarcopenia in daily practice: assessment and management.” BMC Geriatrics 16(1): 170.

    9) Bell, K., Clark, L., Fairhurst, C., Mitchell, N., Lenaghan, E., Blacklock, J., et al. (2016). “Enclosing a pen reduced time to response to questionnaire mailings.” J Clin Epidemiol 74: 144-150.

    10) Bentham, J., Di Cesare, M., Stevens, G. A., Zhou, B., Bixby, H., Cowan, M., et al. (2016). “A century of trends in adult human height.” eLife 5(2016JULY).

    11) Bruyere, O., Beaudart, C., Reginster, J. Y., Buckinx, F., Schoene, D., Hirani, V., et al. (2016). “Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey.” European Geriatric Medicine 7(3): 243-246.

    12) Chakhtoura, M., Nassar, A., Arabi, A., Cooper, C., Harvey, N., Mahfoud, Z., et al. (2016). “Effect of vitamin D replacement on maternal and neonatal outcomes: a randomised controlled trial in pregnant women with hypovitaminosis D. A protocol.” BMJ Open 6(3): e010818.

    13) Compston, J. E., Wyman, A., FitzGerald, G., Adachi, J. D., Chapurlat, R. D., Cooper, C., et al. (2016). “Increase in Fracture Risk Following Unintentional Weight Loss in Postmenopausal Women: The Global Longitudinal Study of Osteoporosis in Women.” Journal of Bone & Mineral Research 31(7): 1466-1472.

    14) Cooper, C., Harvey, N. C., Bishop, N. J., Kennedy, S., Papageorghiou, A. T., Schoenmakers, I., et al. (2016). “Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial.” The Lancet Diabetes & Endocrinology 4(5): 393-402.

    15) Crozier, S. R., Inskip, H. M., Godfrey, K. M., Cooper, C. and Robinson, S. M. (2016). “Nausea and vomiting in early pregnancy: Effects on food intake and diet quality.” Matern Child Nutr.

    16) Curtis, E. M., Harvey, N. C., D’Angelo, S., Cooper, C. S., Ward, K. A., Taylor, P., et al. (2016). “Bone mineral content and areal density, but not bone area, predict an incident fracture risk: a comparative study in a UK prospective cohort.” Archives of Osteoporosis 11(1): 39.

    17) Curtis, E. M., van der Velde, R., Moon, R. J., van den Bergh, J. P., Geusens, P., de Vries, F., et al. (2016). “Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status.” Bone 87: 19-26.

    18) D’Angelo, S., Coggon, D., Harris, E. C., Linaker, C., Sayer, A. A., Gale, C. R., et al. (2016). “Job dissatisfaction and the older worker: baseline findings from the Health and Employment After Fifty study.” Occupational & Environmental Medicine 73(8): 512-519.

    19) Deere, K. C., Hannam, K., Coulson, J., Ireland, A., McPhee, J. S., Moss, C., et al. (2016). “Quantifying Habitual Levels of Physical Activity According to Impact in Older People: Accelerometry Protocol for the VIBE Study.” Journal of Aging & Physical Activity 24(2): 290-295.

    20) Di Cesare, M., Bentham, J., Stevens, G. A., Zhou, B., Danaei, G., Lu, Y., et al. (2016). “Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants.” The Lancet 387(10026): 1377-1396.

    21) Dodds, R. M., Syddall, H. E., Cooper, R., Kuh, D., Cooper, C. and Sayer, A. A. (2016). “Global variation in grip strength: a systematic review and meta-analysis of normative data.” Age & Ageing 45(2): 209-216.

    22) Drew, S., Judge, A., Cooper, C., Javaid, M. K., Farmer, A. and Gooberman-Hill, R. (2016). “Secondary prevention of fractures after hip fracture: a qualitative study of effective service delivery.” Osteoporosis International 27(5): 1719-1727.

    23) Edwards, M. H., Parsons, C., Bruyere, O., Petit Dop, F., Chapurlat, R., Roemer, F. W., et al. (2016). “High Kellgren-Lawrence Grade and Bone Marrow Lesions Predict Worsening Rates of Radiographic Joint Space Narrowing; The SEKOIA Study.” Journal of Rheumatology 43(3): 657-665.

    24) Edwards, M. H., Robinson, D. E., Ward, K. A., Javaid, M. K., Walker-Bone, K., Cooper, C., et al. (2016). “Cluster analysis of bone microarchitecture from high resolution peripheral quantitative computed tomography demonstrates two separate phenotypes associated with high fracture risk in men and women.” Bone 88: 131-137.

    25) El-Heis, S., Crozier, S. R., Robinson, S. M., Harvey, N. C., Cooper, C., Inskip, H. M., et al. (2016). “Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months.” Clinical & Experimental Allergy 46(10): 1337-1343.

    26) Fina-Aviles, F., Medina-Peralta, M., Mendez-Boo, L., Hermosilla, E., Elorza, J. M., Garcia-Gil, M., et al. (2016). “The descriptive epidemiology of rheumatoid arthritis in Catalonia: a retrospective study using routinely collected data.” Clinical Rheumatology 35(3): 751-757.

    27) Fong, W., Holroyd, C., Davidson, B., Armstrong, R., Harvey, N., Dennison, E., et al. (2016). “The effectiveness of a real life dose reduction strategy for tumour necrosis factor inhibitors in ankylosing spondylitis and psoriatic arthritis.” Rheumatology 55(10): 1837-1842.

    28) Forestier-Zhang, L., Watts, L., Turner, A., Teare, H., Kaye, J., Barrett, J., et al. (2016). “Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia.” Orphanet Journal of Rare Diseases 11(1): 1-9.

    29) Gale, C. R., Cooper, C. and Aihie Sayer, A. (2016). “Prevalence and risk factors for falls in older men and women: The English Longitudinal Study of Ageing.” Age & Ageing 45(6): 789-794.

    30) Global Burden of Disease HIV Collaborators, Wang, H., Wolock, T. M., Carter, A., Nguyen, G., Kyu, H. H., et al. (2016). “Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.” The Lancet. HIV 3(8): e361-387.

    31) Global Burden of Disease Pediatrics Collaboration, Kyu, H. H., Pinho, C., Wagner, J. A., Brown, J. C., Bertozzi-Villa, A., et al. (2016). “Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013: Findings From the Global Burden of Disease 2013 Study.” JAMA Pediatrics 170(3): 267-287.

    32) Goulston, L. M., Sanchez-Santos, M. T., D’Angelo, S., Leyland, K. M., Hart, D. J., Spector, T. D., et al. (2016). “A comparison of radiographic anatomic axis knee alignment measurements and cross-sectional associations with knee osteoarthritis.” Osteoarthritis & Cartilage 24(4): 612-622.

    33) Handel, M. N., Moon, R. J., Titcombe, P., Abrahamsen, B., Heitmann, B. L., Calder, P. C., et al. (2016). “Maternal serum retinol and beta-carotene concentrations and neonatal bone mineralization: results from the Southampton Women’s Survey cohort.” American Journal of Clinical Nutrition 104(4): 1183-1188.

    34) Harvey, N. C., Johansson, H., Oden, A., Karlsson, M. K., Rosengren, B. E., Ljunggren, O., et al. (2016). “FRAX predicts incident falls in elderly men: findings from MrOs Sweden.” Osteoporosis International 27(1): 267-274.

    35) Hawley, S., Javaid, M. K., Prieto-Alhambra, D., Lippett, J., Sheard, S., Arden, N. K., et al. (2016). “Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study.” Age & Ageing 45(2): 236-242.

    36) Hawley, S., Javaid, M. K., Rubin, K. H., Judge, A., Arden, N. K., Vestergaard, P., et al. (2016). “Incidence and Predictors of Multiple Fractures Despite High Adherence to Oral Bisphosphonates: A Binational Population-Based Cohort Study.” Journal of Bone & Mineral Research 31(1): 234-244.

    37) Hawley, S., Leal, J., Delmestri, A., Prieto-Alhambra, D., Arden, N. K., Cooper, C., et al. (2016). “Anti-Osteoporosis Medication Prescriptions and Incidence of Subsequent Fracture Among Primary Hip Fracture Patients in England and Wales: An Interrupted Time-Series Analysis.” Journal of Bone & Mineral Research 31(11): 2008-2015.

    38) Herbolsheimer, F., Schaap, L. A., Edwards, M. H., Maggi, S., Otero, A., Timmermans, E. J., et al. (2016). “Physical Activity Patterns among Older Adults with and Without Knee Osteoarthritis in Six European Countries.” Arthritis Care and Research 68(2): 228-236.

    39) Hollis, J. L., Crozier, S. R., Inskip, H. M., Cooper, C., Godfrey, K. M., Robinson, S. M., et al. (2016). “Age at introduction of solid foods and feeding difficulties in childhood: findings from the Southampton Women’s Survey.” British Journal of Nutrition 116(4): 743-750.

    40) Holroyd, C. R., Osmond, C., Barker, D. J., Ring, S. M., Lawlor, D. A., Tobias, J. H., et al. (2016). “Placental Size Is Associated Differentially With Postnatal Bone Size and Density.” Journal of Bone & Mineral Research 31(10): 1855-1864.

    41) Jackson, V. E., Ntalla, I., Sayers, I., Morris, R., Whincup, P., Casas, J. P., et al. (2016). “Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.” Thorax 71(6): 501-509.

    42) Javaid, M. K., Forestier-Zhang, L., Watts, L., Turner, A., Ponte, C., Teare, H., et al. (2016). “The RUDY study platform – a novel approach to patient driven research in rare musculoskeletal diseases.” Orphanet Journal of Rare Diseases 11(1): 1-9.

    43) Jenkins, T., Coutts, L. V., D’Angelo, S., Dunlop, D. G., Oreffo, R. O., Cooper, C., et al. (2016). “Site-Dependent Reference Point Microindentation Complements Clinical Measures for Improved Fracture Risk Assessment at the Human Femoral Neck.” Journal of Bone & Mineral Research 31(1): 196-203.

    44) Kanis, J. A., Harvey, N. C., Cooper, C., Johansson, H., Oden, A., McCloskey, E. V., et al. (2016). “A systematic review of intervention thresholds based on FRAX : A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation.” Archives of Osteoporosis 11(1): 25.

    45) Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Spector, T. D., Hart, D., et al. (2016). “Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women.” Annals of the Rheumatic Diseases 75(10): 1749-1756.

    46) Kuh, D., Muthuri, S., Cooper, R., Moore, A., Mackinnon, K., Cooper, C., et al. (2016). “Menopause, Reproductive Life, Hormone Replacement Therapy, and Bone Phenotype at Age 60-64 Years: A British Birth Cohort.” Journal of Clinical Endocrinology & Metabolism 101(10): 3827-3837.

    47) Kuh, D., Muthuri, S. G., Moore, A., Cole, T. J., Adams, J. E., Cooper, C., et al. (2016). “Pubertal timing and bone phenotype in early old age: findings from a British birth cohort study.” International Journal of Epidemiology 45(4): 1113-1124.

    48) Lalmohamed, A., van Staa, T. P., Vestergaard, P., Leufkens, H. G., de Boer, A., Emans, P., et al. (2016). “Statins and Risk of Lower Limb Revision Surgery: The Influence of Differences in Study Design Using Electronic Health Records From the United Kingdom and Denmark.” American Journal of Epidemiology 184(1): 58-66.

    49) Lawrence, W., Black, C., Tinati, T., Cradock, S., Begum, R., Jarman, M., et al. (2016). “‘Making every contact count’: Evaluation of the impact of an intervention to train health and social care practitioners in skills to support health behaviour change.” Journal of Health Psychology 21(2): 138-151.

    50) Leal, J., Gray, A. M., Prieto-Alhambra, D., Arden, N. K., Cooper, C., Javaid, M. K., et al. (2016). “Impact of hip fracture on hospital care costs: a population-based study.” Osteoporosis International 27(2): 549-558.

    51) Lewis, A., Lee, J. Y., Donaldson, A. V., Natanek, S. A., Vaidyanathan, S., Man, W. D., et al. (2016). “Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD.” Journal of Cachexia, Sarcopenia and Muscle 7(3): 330-344.

    52) Leyland, K. M., Judge, A., Javaid, M. K., Diez-Perez, A., Carr, A., Cooper, C., et al. (2016). “Obesity and the Relative Risk of Knee Replacement Surgery in Patients With Knee Osteoarthritis: A Prospective Cohort Study.” Arthritis & Rheumatology 68(4): 817-825.

    53) Litwic, A. E., Clynes, M., Denison, H. J., Jameson, K. A., Edwards, M. H., Sayer, A. A., et al. (2016). “Non-invasive Assessment of Lower Limb Geometry and Strength Using Hip Structural Analysis and Peripheral Quantitative Computed Tomography: A Population-Based Comparison.” Calcified Tissue International 98(2): 158-164.

    54) Moon, R. J., Harvey, N. C., Cooper, C., D’Angelo, S., Crozier, S. R., Inskip, H. M., et al. (2016). “Determinants of the Maternal 25-Hydroxyvitamin D Response to Vitamin D Supplementation During Pregnancy.” Journal of Clinical Endocrinology & Metabolism 101(12): 5012-5020.

    55) Moon, R. J., Harvey, N. C., Curtis, E. M., de Vries, F., van Staa, T. and Cooper, C. (2016). “Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom.” Bone 85: 9-14.

    56) Moon, R. J., Lim, A., Farmer, M., Segaran, A., Clarke, N. M., Harvey, N. C., et al. (2016). “Validity of parental recall of children’s fracture: implications for investigation of childhood osteoporosis.” Osteoporosis International 27(2): 809-813.

    57) Murray, R., Bryant, J., Titcombe, P., Barton, S. J., Inskip, H., Harvey, N. C., et al. (2016). “DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years.” Clinical Epigenetics 8(1).

    58) North, T. L., Ben-Shlomo, Y., Cooper, C., Deary, I. J., Gallacher, J., Kivimaki, M., et al. (2016). “A study of common Mendelian disease carriers across ageing British cohorts: meta-analyses reveal heterozygosity for alpha 1-antitrypsin deficiency increases respiratory capacity and height.” Journal of Medical Genetics 53(4): 280-288.

    59) Okely, J. A., Cooper, C. and Gale, C. R. (2016). “Wellbeing and Arthritis Incidence: the Survey of Health, Ageing and Retirement in Europe.” Annals of Behavioral Medicine 50(3): 419-426.

    60) Paccou, J., Edwards, M. H., Patsch, J. M., Jameson, K. A., Ward, K. A., Moss, C., et al. (2016). “Lower leg arterial calcification assessed by high-resolution peripheral quantitative computed tomography is associated with bone microstructure abnormalities in women.” Osteoporosis International 27(11): 3279-3287.

    61) Paccou, J., Ward, K. A., Jameson, K. A., Dennison, E. M., Cooper, C. and Edwards, M. H. (2016). “Bone Microarchitecture in Men and Women with Diabetes: The Importance of Cortical Porosity.” Calcified Tissue International 98(5): 465-473.

    62) Pilgrim, A. L., Baylis, D., Jameson, K. A., Cooper, C., Sayer, A. A., Robinson, S. M., et al. (2016). “Measuring Appetite with the Simplified Nutritional Appetite Questionnaire Identifies Hospitalised Older People at Risk of Worse Health Outcomes.” Journal of Nutrition, Health & Aging 20(1): 3-7.

    63) Reyes, C., Leyland, K. M., Peat, G., Cooper, C., Arden, N. K. and Prieto-Alhambra, D. (2016). “Association Between Overweight and Obesity and Risk of Clinically Diagnosed Knee, Hip, and Hand Osteoarthritis: A Population-Based Cohort Study.” Arthritis & Rheumatology 68(8): 1869-1875.

    64) Reyes, C., Pottegard, A., Schwarz, P., Javaid, M. K., Van Staa, T. P., Cooper, C., et al. (2016). “Real-Life and RCT Participants: Alendronate Users Versus FITs’ Trial Eligibility Criterion.” Calcified Tissue International 99(3): 243-249.

    65) Siviero, P., Zambon, S., Limongi, F., Castell, M. V., Cooper, C., Deeg, D. J., et al. (2016). “How Hand Osteoarthritis, Comorbidity, and Pain Interact to Determine Functional Limitation in Older People: Observations From the European Project on OSteoArthritis Study.” Arthritis & Rheumatology 68(11): 2662-2670.

    66) Syddall, H. E., Westbury, L. D., Simmonds, S. J., Robinson, S., Cooper, C. and Sayer, A. A. (2016). “Understanding poor health behaviours as predictors of different types of hospital admission in older people: findings from the Hertfordshire Cohort Study.” Journal of Epidemiology & Community Health 70(3): 292-298.

    67) Timmermans, E. J., van der Pas, S., Cooper, C., Schaap, L. A., Edwards, M. H., Deeg, D. J., et al. (2016). “The neighbourhood environment and use of neighbourhood resources in older adults with and without lower limb osteoarthritis: results from the Hertfordshire Cohort Study.” Clinical Rheumatology 35(11): 2797-2805.

    68) van der Pas, S., Schaap, L. A., Castell, M. V., Cooper, C., Denkinger, M., Edwards, M. H., et al. (2016). “Availability and use of neighborhood resources by older people with osteoarthritis: Results from the European Project on OSteoArthritis.” Health and Place 37: 1-7.

    69) van der Velde, R. Y., Wyers, C. E., Curtis, E. M., Geusens, P. P., van den Bergh, J. P., de Vries, F., et al. (2016). “Secular trends in fracture incidence in the UK between 1990 and 2012.” Osteoporosis International 27(11): 3197-3206.

    70) van Schoor, N. M., Zambon, S., Castell, M. V., Cooper, C., Denkinger, M., Dennison, E. M., et al. (2016). “Impact of clinical osteoarthritis of the hip, knee and hand on self-rated health in six European countries: the European Project on OSteoArthritis.” Quality of Life Research 25(6): 1423-1432.

    71) Veronese, N., Stubbs, B., Noale, M., Solmi, M., Luchini, C., Smith, T. O., et al. (2016). “Adherence to a Mediterranean diet is associated with lower prevalence of osteoarthritis: Data from the osteoarthritis initiative.” Clinical Nutrition 8: 8.

    72) Vogel, C., Ntani, G., Inskip, H., Barker, M., Cummins, S., Cooper, C., et al. (2016). “Education and the Relationship Between Supermarket Environment and Diet.” American Journal of Preventive Medicine 51(2): e27-34.

    73) Vogel, C., Parsons, C., Godfrey, K., Robinson, S., Harvey, N. C., Inskip, H., et al. (2016). “Greater access to fast-food outlets is associated with poorer bone health in young children.” Osteoporosis International 27(3): 1011-1019.

    74) Walker-Bone, K., D’Angelo, S., Syddall, H. E., Palmer, K. T., Cooper, C., Coggon, D., et al. (2016). “Heavy manual work throughout the working lifetime and muscle strength among men at retirement age.” Occupational & Environmental Medicine 73(4): 284-286.

    75) Walker-Bone, K., Harvey, N. C., Ntani, G., Tinati, T., Jones, G. T., Smith, B. H., et al. (2016). “Chronic widespread bodily pain is increased among individuals with history of fracture: findings from UK Biobank.” Archives of Osteoporosis 11: 1.

    76) Westbury, L. D., Syddall, H. E., Simmonds, S. J., Cooper, C. and Sayer, A. A. (2016). “Identification of risk factors for hospital admission using multiple-failure survival models: a toolkit for researchers.” BMC Medical Research Methodology 16: 46.

    77) Zhang, J., Jameson, K., Sayer, A. A., Robinson, S., Cooper, C. and Dennison, E. (2016). “Accumulation of risk factors associated with poor bone health in older adults.” Archives of Osteoporosis 11: 3.

    78) Zhou, B., Lu, Y., Hajifathalian, K., Bentham, J., Di Cesare, M., Danaei, G., et al. (2016). “Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants.” The Lancet 387(10027).

    2015

    1) Abrahamsen, B., Osmond, C. and Cooper, C. (2015). “Life Expectancy in Patients Treated for Osteoporosis: Observational Cohort Study Using National Danish Prescription Data.” J Bone Miner Res 30(9): 1553-1559.

    2) Armbrecht, G., Felsenberg, D., Ganswindt, M., Lunt, M., Kaptoge, S. K., Abendroth, K., et al. (2015). “Vertebral Scheuermann’s disease in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over.” Osteoporosis International 26(10): 2509-2519.

    3) Baylis, D., Syddall, H. E., Jameson, K. A., Cooper, C., Lord, J. M., Roberts, H. C., et al. (2015). “Cachexia, sarcopenia, inflammaging and outcomes in hospitalised older people (the CaSIO study): Study protocol and preliminary results.” European Geriatric Medicine 6(5): 495-501.

    5) Bishop, F. L., Yardley, L., Prescott, P., Cooper, C., Little, P. and Lewith, G. T. (2015). “Psychological covariates of longitudinal changes in back-related disability in patients undergoing acupuncture.” Clinical Journal of Pain 31(3): 254-264.

    6) Bryant, J., Hanson, M., Peebles, C., Davies, L., Inskip, H., Robinson, S., et al. (2015). “Higher oily fish consumption in late pregnancy is associated with reduced aortic stiffness in the child at age 9 years.” Circulation Research 116(7): 1202-1205.

    7) Carbonell-Abella, C., Pages-Castella, A., Javaid, M. K., Nogues, X., Farmer, A. J., Cooper, C., et al. (2015). “Early (1-year) Discontinuation of Different Anti-osteoporosis Medications Compared: A Population-Based Cohort Study.” Calcified Tissue International 97(6): 535-541.

    8) Cleal, J. K., Day, P. E., Simner, C. L., Barton, S. J., Mahon, P. A., Inskip, H. M., et al. (2015). “Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women’s Survey.” British Journal of Nutrition 113(12): 1903-1910.

    9) Clynes, M. A., Edwards, M. H., Buehring, B., Dennison, E. M., Binkley, N. and Cooper, C. (2015). “Definitions of Sarcopenia: Associations with Previous Falls and Fracture in a Population Sample.” Calcified Tissue International 97(5): 445-452.

    10) Colebatch-Bourn, A. N., Conaghan, P. G., Arden, N. K., Cooper, C., Dougados, M. and Edwards, C. J. (2015). “Raising the quality of rheumatology management recommendations: lessons from the EULAR process 10 years after provision of standard operating procedures.” Rheumatology 54(8): 1392-1396.

    11) Coutts, L. V., Jenkins, T., Li, T., Dunlop, D. G., Oreffo, R. O., Cooper, C., et al. (2015). “Variability in reference point microindentation and recommendations for testing cortical bone: location, thickness and orientation heterogeneity.” Journal of the Mechanical Behavior of Biomedical Materials 46: 292-304.

    12) Culliford, D., Maskell, J., Judge, A., Cooper, C., Prieto-Alhambra, D., Arden, N. K., et al. (2015). “Future projections of total hip and knee arthroplasty in the UK: results from the UK Clinical Practice Research Datalink.” Osteoarthritis & Cartilage 23(4): 594-600.

    13) Danaei, G., Fahimi, S., Lu, Y., Zhou, B., Hajifathalian, K., Cesare, M. D., et al. (2015). “Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: A pooled analysis of 96 population-based studies with 331 288 participants.” The Lancet Diabetes and Endocrinology 3(8): 624-637.

    14) Davey, T., Lanham-New, S. A., Shaw, A. M., Cobley, R., Allsopp, A. J., Hajjawi, M. O., et al. (2015). “Fundamental differences in axial and appendicular bone density in stress fractured and uninjured Royal Marine recruits–a matched case-control study.” Bone 73: 120-126.

    15) Day, P. E., Ntani, G., Crozier, S. R., Mahon, P. A., Inskip, H. M., Cooper, C., et al. (2015). “Maternal Factors Are Associated with the Expression of Placental Genes Involved in Amino Acid Metabolism and Transport.” PLoS One 10(12): e0143653.

    16) Dennison, E. M., Rubin, K. H., Schwarz, P., Harvey, N. C., Bone, K. W., Cooper, C., et al. (2015). “Is allopurinol use associated with an excess risk of osteoporotic fracture? A National Prescription Registry study.” Arch Osteoporos 10: 36.

    17) Di Angelantonio, E., Kaptoge, S., Wormser, D., Willeit, P., Butterworth, A. S., Bansal, N., et al. (2015). “Association of Cardiometabolic Multimorbidity With Mortality.” Jama 314(1): 52-60.

    18) Drew, S., Gooberman-Hill, R., Farmer, A., Graham, L., Javaid, M. K., Cooper, C., et al. (2015). “Making the case for a fracture liaison service: a qualitative study of the experiences of clinicians and service managers.” BMC Musculoskeletal Disorders 16: 274.

    19) Drew, S., Judge, A., May, C., Farmer, A., Cooper, C., Javaid, M. K., et al. (2015). “Implementation of secondary fracture prevention services after hip fracture: a qualitative study using extended Normalization Process Theory.” Implementation Science 10: 57.

    20) Edwards, M. H., Ward, K. A., Ntani, G., Parsons, C., Thompson, J., Sayer, A. A., et al. (2015). “Lean mass and fat mass have differing associations with bone microarchitecture assessed by high resolution peripheral quantitative computed tomography in men and women from the Hertfordshire Cohort Study.” Bone 81: 145-151.

    21) Eymard, F., Parsons, C., Edwards, M. H., Petit-Dop, F., Reginster, J. Y., Bruyere, O., et al. (2015). “Diabetes is a risk factor for knee osteoarthritis progression.” Osteoarthritis & Cartilage 23(6): 851-859.

    22) Forouzanfar, M. H., Alexander, L., Anderson, H. R., Bachman, V. F., Biryukov, S., Brauer, M., et al. (2015). “Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013.” The Lancet 386(10010): 2287-2323.

    23) Fox, B., Henwood, T., Schaap, L., Bruyere, O., Reginster, J. Y., Beaudart, C., et al. (2015). “Adherence to a standardized protocol for measuring grip strength and appropriate cut-off values in adults over 65 years with sarcopenia: A systematic review protocol.” JBI Database of Systematic Reviews and Implementation Reports 13(10): 50-59.

    24) Gale, C. R., Cooper, C. and Sayer, A. A. (2015). “Prevalence of frailty and disability: findings from the English Longitudinal Study of Ageing.” Age & Ageing 44(1): 162-165.

    25) Hardcastle, S. A., Dieppe, P., Gregson, C. L., Arden, N. K., Spector, T. D., Hart, D. J., et al. (2015). “Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis.” Bone 71: 171-179.

    26) Jarman, M., Inskip, H. M., Ntani, G., Cooper, C., Baird, J., Robinson, S. M., et al. (2015). “Influences on the diet quality of pre-school children: importance of maternal psychological characteristics.” Public Health Nutr 18(11): 2001-2010.

    27) Jarman, M., Ogden, J., Inskip, H., Lawrence, W., Baird, J., Cooper, C., et al. (2015). “How do mothers manage their preschool children’s eating habits and does this change as children grow older? A longitudinal analysis.” Appetite 95: 466-474.

    28) Javaid, M. K., Kyer, C., Mitchell, P. J., Chana, J., Moss, C., Edwards, M. H., et al. (2015). “Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture Best Practice Framework tool.” Osteoporosis International 26(11): 2573-2578.

    29) Jenkins, T., Coutts, L. V., Dunlop, D. G., Oreffo, R. O., Cooper, C., Harvey, N. C., et al. (2015). “Variability in reference point microindentation and recommendations for testing cortical bone: maximum load, sample orientation, mode of use, sample preparation and measurement spacing.” J Mech Behav Biomed Mater 42: 311-324.

    30) Khan, A. A., Morrison, A., Hanley, D. A., Felsenberg, D., McCauley, L. K., O’Ryan, F., et al. (2015). “Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus.” Journal of Bone & Mineral Research 30(1): 3-23.

    31) Kiran, A., Bottomley, N., Biant, L. C., Javaid, M. K., Carr, A. J., Cooper, C., et al. (2015). “Variations In Good Patient Reported Outcomes After Total Knee Arthroplasty.” Journal of Arthroplasty 30(8): 1364-1371.

    32) Lillycrop, K. A., Costello, P. M., Teh, A. L., Murray, R. J., Clarke-Harris, R., Barton, S. J., et al. (2015). “Association between perinatal methylation of the neuronal differentiation regulator HES1 and later childhood neurocognitive function and behaviour.” International Journal of Epidemiology 44(4): 1263-1276.

    33) Macdonald-Wallis, C., Silverwood, R. J., de Stavola, B. L., Inskip, H., Cooper, C., Godfrey, K. M., et al. (2015). “Antenatal blood pressure for prediction of pre-eclampsia, preterm birth, and small for gestational age babies: development and validation in two general population cohorts.” BMJ 351: h5948.

    34) Mansour, S., Tocheva, A. S., Sanderson, J. P., Goulston, L. M., Platten, H., Serhal, L., et al. (2015). “Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis.” J Immunol 195(12): 5582-5591.

    35) Marks, J. L., Holroyd, C. R., Dimitrov, B. D., Armstrong, R. D., Calogeras, A., Cooper, C., et al. (2015). “Does combined clinical and ultrasound assessment allow selection of individuals with rheumatoid arthritis for sustained reduction of anti-tumor necrosis factor therapy?” Arthritis Care Res (Hoboken) 67(6): 746-753.

    36) Martinez-Laguna, D., Tebe, C., Javaid, M. K., Nogues, X., Arden, N. K., Cooper, C., et al. (2015). “Incident type 2 diabetes and hip fracture risk: a population-based matched cohort study.” Osteoporosis International 26(2): 827-833.

    37) McCloskey, E., Kanis, J. A., Johansson, H., Harvey, N., Oden, A., Cooper, A., et al. (2015). “FRAX-based assessment and intervention thresholds–an exploration of thresholds in women aged 50 years and older in the UK.” Osteoporosis International 26(8): 2091-2099.

    38) Menni, C., Graham, D., Kastenmuller, G., Alharbi, N. H., Alsanosi, S. M., McBride, M., et al. (2015). “Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate.” Hypertension 66(2): 422-429.

    39) Moon, R. J., Cole, Z. A., Crozier, S. R., Curtis, E. M., Davies, J. H., Gregson, C. L., et al. (2015). “Longitudinal changes in lean mass predict pQCT measures of tibial geometry and mineralisation at 6-7 years.” Bone 75: 105-110.

    40) Moon, R. J., Crozier, S. R., Dennison, E. M., Davies, J. H., Robinson, S. M., Inskip, H. M., et al. (2015). “Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation.” Am J Clin Nutr 102(5): 1081-1087.

    41) Moon, R. J., Lim, A., Farmer, M., Segaran, A., Clarke, N. M., Dennison, E. M., et al. (2015). “Differences in childhood adiposity influence upper limb fracture site.” Bone 79: 88-93.

    42) Murray, C. J. L., Barber, R. M., Foreman, K. J., Ozgoren, A. A., Abd-Allah, F., Abera, S. F., et al. (2015). “Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition.” The Lancet 386(10009): 2145-2191.

    43) Naghavi, M., Wang, H., Lozano, R., Davis, A., Liang, X., Zhou, M., et al. (2015). “Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013.” The Lancet 385(9963): 117-171.

    44) Nead, K. T., Li, A., Wehner, M. R., Neupane, B., Gustafsson, S., Butterworth, A., et al. (2015). “Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.” Human Molecular Genetics 24(12): 3582-3594.

    45) Newton, J. N., Briggs, A. D., Murray, C. J., Dicker, D., Foreman, K. J., Wang, H., et al. (2015). “Changes in health in England, with analysis by English regions and areas of deprivation, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.” Lancet 386(10010): 2257-2274.

    46) North, T. L., Palmer, T. M., Lewis, S. J., Cooper, R., Power, C., Pattie, A., et al. (2015). “Effect of smoking on physical and cognitive capability in later life: A multicohort study using observational and genetic approaches.” BMJ Open 5 (12) (no pagination)(e008393).

    47) Ntani, G., Day, P. F., Baird, J., Godfrey, K. M., Robinson, S. M., Cooper, C., et al. (2015). “Maternal and early life factors of tooth emergence patterns and number of teeth at 1 and 2 years of age.” Journal of Developmental Origins of Health and Disease 6(4): 299-307.

    48) Okubo, H., Crozier, S. R., Harvey, N. C., Godfrey, K. M., Inskip, H. M., Cooper, C., et al. (2015). “Diet quality across early childhood and adiposity at 6 years: the Southampton Women’s Survey.” International Journal of Obesity 39(10): 1456-1462.

    49) Paccou, J., Edwards, M. H., Ward, K., Jameson, K., Moon, R., Dennison, E., et al. (2015). “Relationships between bone geometry, volumetric bone mineral density and bone microarchitecture of the distal radius and tibia with alcohol consumption.” Bone 78: 122-129.

    50) Paccou, J., Edwards, M. H., Ward, K. A., Jameson, K. A., Moss, C. L., Harvey, N. C., et al. (2015). “Ischemic heart disease is associated with lower cortical volumetric bone mineral density of distal radius.” Osteoporos Int 26(7): 1893-1901.

    51) Palmer, K. T., Walker-Bone, K., Harris, E. C., Linaker, C., D’Angelo, S., Sayer, A. A., et al. (2015). “Health and Employment after Fifty (HEAF): a new prospective cohort study.” BMC Public Health 15(1): 1071.

    52) Parsons, C., Clynes, M., Syddall, H., Jagannath, D., Litwic, A., van der Pas, S., et al. (2015). “How well do radiographic, clinical and self-reported diagnoses of knee osteoarthritis agree? Findings from the Hertfordshire cohort study.” Springerplus 4: 177.

    53) Patel, H. P., White, M. C., Westbury, L., Syddall, H. E., Stephens, P. J., Clough, G. F., et al. (2015). “Skeletal muscle morphology in sarcopenia defined using the EWGSOP criteria: findings from the Hertfordshire Sarcopenia Study (HSS).” BMC Geriatr 15: 171.

    54) Prieto-Alhambra, D., Javaid, M. K., Judge, A., Maskell, J., Cooper, C., Arden, N. K., et al. (2015). “Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.” Ann Rheum Dis 74(3): 557-563.

    55) Prieto-Alhambra, D., Munoz-Ortego, J., De Vries, F., Vosse, D., Arden, N. K., Bowness, P., et al. (2015). “Ankylosing spondylitis confers substantially increased risk of clinical spine fractures: a nationwide case-control study.” Osteoporosis International 26(1): 85-91.

    56) Reppe, S., Wang, Y., Thompson, W. K., McEvoy, L. K., Schork, A. J., Zuber, V., et al. (2015). “Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci.” PLoS ONE 10 (12) (no pagination)(e0144531).

    57) Reyes, C., Garcia-Gil, M., Elorza, J. M., Mendez-Boo, L., Hermosilla, E., Javaid, M. K., et al. (2015). “Socio-economic status and the risk of developing hand, hip or knee osteoarthritis: a region-wide ecological study.” Osteoarthritis & Cartilage 23(8): 1323-1329.

    58) Rice, S. A., Carpenter, M., Fityan, A., Vearncombe, L. M., Ardern-Jones, M., Jackson, A. A., et al. (2015). “Limited exposure to ambient ultraviolet radiation and 25-hydroxyvitamin D levels: a systematic review.” British Journal of Dermatology 172(3): 652-661.

    59) Roberts, H. C., Syddall, H. E., Butchart, J. W., Stack, E. L., Cooper, C. and Sayer, A. A. (2015). “The Association of Grip Strength With Severity and Duration of Parkinson’s: A Cross-Sectional Study.” Neurorehabilitation & Neural Repair 29(9): 889-896.

    60) Robinson, S. M., Crozier, S. R., Harvey, N. C., Barton, B. D., Law, C. M., Godfrey, K. M., et al. (2015). “Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention.” Am J Clin Nutr 101(2): 368-375.

    61) Robison, J., Pilgrim, A. L., Rood, G., Diaper, N., Elia, M., Jackson, A. A., et al. (2015). “Can trained volunteers make a difference at mealtimes for older people in hospital? A qualitative study of the views and experience of nurses, patients, relatives and volunteers in the Southampton Mealtime Assistance Study.” International Journal of Older People Nursing 10(2): 136-145.

    62) Simmonds, S. J., Syddall, H. E., Westbury, L. D., Dodds, R. M., Cooper, C. and Aihie Sayer, A. (2015). “Grip strength among community-dwelling older people predicts hospital admission during the following decade.” Age Ageing 44(6): 954-959.

    63) Syddall, H. E., Westbury, L. D., Cooper, C. and Sayer, A. A. (2015). “Self-reported walking speed: a useful marker of physical performance among community-dwelling older people?” Journal of the American Medical Directors Association 16(4): 323-328.

    64) Vos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., et al. (2015). “Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013.” The Lancet 386(9995): 743-800.

    65) Wijnands, J. M., van Durme, C. M., Driessen, J. H., Boonen, A., Klop, C., Leufkens, B., et al. (2015). “Individuals With Type 2 Diabetes Mellitus Are at an Increased Risk of Gout But This Is Not Due to Diabetes: A Population-Based Cohort Study.” Medicine 94(32): e1358.

    66) Wilson, N., Sanchez-Riera, L., Morros, R., Diez-Perez, A., Javaid, M. K., Cooper, C., et al. (2015). “Drug utilization in patients with OA: a population-based study.” Rheumatology 54(5): 860-867.

    2014

    1) Agyapong-Badu, S., Warner, M., Samuel, D., Narici, M., Cooper, C. and Stokes, M. (2014). “Anterior thigh composition measured using ultrasound imaging to quantify relative thickness of muscle and non-contractile tissue: a potential biomarker for musculoskeletal health.” Physiological Measurement 35(10): 2165-2176.

    2) Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., et al. (2014). “Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme.” Age 36(4): 9673.

    3) Azagra, R., Lopez-Exposito, F., Martin-Sanchez, J. C., Aguye, A., Moreno, N., Cooper, C., et al. (2014). “Changing trends in the epidemiology of hip fracture in Spain.” Osteoporosis International 25(4): 1267-1274.

    4) Baird, J., Jarman, M., Lawrence, W., Black, C., Davies, J., Tinati, T., et al. (2014). “The effect of a behaviour change intervention on the diets and physical activity levels of women attending Sure Start Children’s Centres: results from a complex public health intervention.” BMJ Open 4(7): e005290.

    5) Baylis, D., Ntani, G., Edwards, M. H., Syddall, H. E., Bartlett, D. B., Dennison, E. M., et al. (2014). “Inflammation, telomere length, and grip strength: a 10-year longitudinal study.” Calcified Tissue International 95(1): 54-63.

    6) Black, C., Lawrence, W., Cradock, S., Ntani, G., Tinati, T., Jarman, M., et al. (2014). “Healthy conversation skills: increasing competence and confidence in front-line staff.” Public Health Nutrition 17(3): 700-707.

    7) Black, C., Ntani, G., Inskip, H., Cooper, C., Cummins, S., Moon, G., et al. (2014). “Measuring the healthfulness of food retail stores: variations by store type and neighbourhood deprivation.” International Journal of Behavioral Nutrition & Physical Activity 11: 69.

    8) Bruyere, O., Reginster, J. Y., Bellamy, N., Chapurlat, R., Richette, P., Cooper, C., et al. (2014). “Clinically meaningful effect of strontium ranelate on symptoms in knee osteoarthritis: a responder analysis.” Rheumatology 53(8): 1457-1464.

    9) Bultink, I. E., Harvey, N. C., Lalmohamed, A., Cooper, C., Lems, W. F., van Staa, T. P., et al. (2014). “Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom.” Osteoporosis International 25(4): 1275-1283.

    10) Clynes, M. A., Parsons, C., Edwards, M. H., Jameson, K. A., Harvey, N. C., Sayer, A. A., et al. (2014). “Further evidence of the developmental origins of osteoarthritis: results from the Hertfordshire Cohort Study.” Journal of Developmental Origins of Health and Disease 5(6): 453-458.

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    13) Cooper, C., Fox, K. M. and Borer, J. S. (2014). “Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: a nested case-control study in the CPRD.” Osteoporosis International 25(2): 737-745.

    14) Cooper, R., Stafford, M., Hardy, R., Aihie Sayer, A., Ben-Shlomo, Y., Cooper, C., et al. (2014). “Physical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts.” Age 36(1): 445-456.

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    16) Dennison, E. M., Jameson, K. A., Edwards, M. H., Denison, H. J., Aihie Sayer, A. and Cooper, C. (2014). “Peripheral quantitative computed tomography measures are associated with adult fracture risk: the Hertfordshire Cohort Study.” Bone 64: 13-17.

    17) Diez-Perez, A., Adachi, J. D., Adami, S., Anderson, F. A., Jr., Boonen, S., Chapurlat, R., et al. (2014). “Risk factors for treatment failure with antiosteoporosis medication: the global longitudinal study of osteoporosis in women (GLOW).” Journal of Bone & Mineral Research 29(1): 260-267.

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    25) Gale, C. R., Allerhand, M., Sayer, A. A., Cooper, C. and Deary, I. J. (2014). “The dynamic relationship between cognitive function and walking speed: the English Longitudinal Study of Ageing.” Age 36(4): 9682.

    26) Gale, C. R., Cooper, C., Deary, I. J. and Aihie Sayer, A. (2014). “Psychological well-being and incident frailty in men and women: the English Longitudinal Study of Ageing.” Psychological Medicine 44(4): 697-706.

    27) Gale, C. R., Cooper, C. and Sayer, A. A. (2014). “Framingham cardiovascular disease risk scores and incident frailty: the English Longitudinal Study of Ageing.” Age 36(4): 9692.

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    40) Jones, L. E., Roberts, L. C., Little, P. S., Mullee, M. A., Cleland, J. A. and Cooper, C. (2014). “Shared decision-making in back pain consultations: an illusion or reality?” European Spine Journal 23 Suppl 1: S13-19.

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    47) Mathews, R. J., Robinson, J. I., Battellino, M., Wong, C., Taylor, J. C., Eyre, S., et al. (2014). “Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.” Ann Rheum Dis 73(6): 1202-1210.

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    49) Moayyeri, A., Hsu, Y. H., Karasik, D., Estrada, K., Xiao, S. M., Nielson, C., et al. (2014). “Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.” Human Molecular Genetics 23(11): 3054-3068.

    50) Moon, R. J., Gilbert, R. D., Page, A., Murphy, L., Taylor, P., Cooper, C., et al. (2014). “Children with nephrotic syndrome have greater bone area but similar volumetric bone mineral density to healthy controls.” Bone 58: 108-113.

    51) Munoz-Ortego, J., Vestergaard, P., Rubio, J. B., Wordsworth, P., Judge, A., Javaid, M. K., et al. (2014). “Ankylosing spondylitis is associated with an increased risk of vertebral and nonvertebral clinical fractures: a population-based cohort study.” J Bone Miner Res 29: 1770-1776.

    52) Murray, C. J., Ortblad, K. F., Guinovart, C., Lim, S. S., Wolock, T. M., Roberts, D. A., et al. (2014). “Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.[Erratum appears in Lancet. 2014 Sep 13;384(9947):956], [Erratum appears in Lancet. 2014 Oct 25;384(9953):1504].” Lancet 384(9947): 1005-1070.

    53) Neogi, T., Soni, A., Doherty, S. A., Laslett, L. L., Maciewicz, R. A., Hart, D. J., et al. (2014). “Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis.” Annals of the Rheumatic Diseases 73(1): 315-317.

    54) Nowson, C. A., Crozier, S. R., Robinson, S. M., Godfrey, K. M., Lawrence, W. T., Law, C. M., et al. (2014). “Association of early childhood abdominal circumference and weight gain with blood pressure at 36 months of age: secondary analysis of data from a prospective cohort study.” BMJ Open 4(7): e005412.

    55) Oei, L., Hsu, Y. H., Styrkarsdottir, U., Eussen, B. H., de Klein, A., Peters, M. J., et al. (2014). “A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.” Journal of Medical Genetics 51(2): 122-131.

    56) Okubo, H., Crozier, S. R., Harvey, N. C., Godfrey, K. M., Inskip, H. M., Cooper, C., et al. (2014). “Maternal dietary glycemic index and glycemic load in early pregnancy are associated with offspring adiposity in childhood: the Southampton Women’s Survey.” American Journal of Clinical Nutrition 100(2): 676-683.

    58) Okubo, H., Syddall, H. E., Phillips, D. I., Sayer, A. A., Dennison, E. M., Cooper, C., et al. (2014). “Dietary total antioxidant capacity is related to glucose tolerance in older people: the Hertfordshire Cohort Study.” Nutrition Metabolism & Cardiovascular Diseases 24(3): 301-308.

    59) Palmer, K. T., D’Angelo, S., Syddall, H., Griffin, M. J., Cooper, C. and Coggon, D. (2014). “Dupuytren’s contracture and occupational exposure to hand-transmitted vibration.” Occupational & Environmental Medicine 71(4): 241-245.

    60) Panoutsopoulou, K., Metrustry, S., Doherty, S. A., Laslett, L. L., Maciewicz, R. A., Hart, D. J., et al. (2014). “The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study.” Annals of the Rheumatic Diseases 73(12): 2082-2086.

    61) Patel, H. P., Al-Shanti, N., Davies, L. C., Barton, S. J., Grounds, M. D., Tellam, R. L., et al. (2014). “Lean mass, muscle strength and gene expression in community dwelling older men: findings from the Hertfordshire Sarcopenia Study (HSS).” Calcified Tissue International 95(4): 308-316.

    62) Pike, K. C., Davis, S. A., Collins, S. A., Lucas, J. S., Inskip, H. M., Wilson, S. J., et al. (2014). “Prenatal development is linked to bronchial reactivity: epidemiological and animal model evidence.” Scientific Reports 4: 4705.

    63) Piscitelli, P., Brandi, M., Cawston, H., Gauthier, A., Kanis, J. A., Compston, J., et al. (2014). “Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: estimations from a disease model.” Calcified Tissue International 95(5): 419-427.

    64) Pouwels, S., de Boer, A., Leufkens, H. G., Weber, W. E., Cooper, C. and de Vries, F. (2014). “Risk of fracture in patients with Charcot-Marie-Tooth disease.” Muscle & Nerve 50(6): 919-924.

    65) Pouwels, S., de Boer, A., Leufkens, H. G., Weber, W. E., Cooper, C., van Onzenoort, H. A., et al. (2014). “Risk of fracture in patients with muscular dystrophies.” Osteoporosis International 25(2): 509-518.

    66) Prieto-Alhambra, D., Guerri-Fernandez, R., De Vries, F., Lalmohamed, A., Bazelier, M., Starup-Linde, J., et al. (2014). “HIV infection and its association with an excess risk of clinical fractures: a nationwide case-control study.” Journal of Acquired Immune Deficiency Syndromes: JAIDS 66(1): 90-95.

    67) Prieto-Alhambra, D., Judge, A., Arden, N. K., Cooper, C., Lyles, K. W. and Javaid, M. K. (2014). “Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial.” Osteoporosis International 25(1): 77-83.

    68) Prieto-Alhambra, D., Judge, A., Javaid, M. K., Cooper, C., Diez-Perez, A. and Arden, N. K. (2014). “Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints.” Annals of the Rheumatic Diseases 73(9): 1659-1664.

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    71) Qi, Q., Kilpelainen, T. O., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., et al. (2014). “FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.” Human Molecular Genetics 23(25): 6961-6972.

    72) Reyes, C., Estrada, P., Nogues, X., Orozco, P., Cooper, C., Diez-Perez, A., et al. (2014). “The impact of common co-morbidities (as measured using the Charlson index) on hip fracture risk in elderly men: a population-based cohort study.[Erratum appears in Osteoporos Int. 2014 Sep;25(9):2333 Note: Macias, J G [corrected to Gonzalez-Macias, J]].” Osteoporosis International 25(6): 1751-1758.

    73) Roberts, H. C., De Wet, S., Porter, K., Rood, G., Diaper, N., Robison, J., et al. (2014). “The feasibility and acceptability of training volunteer mealtime assistants to help older acute hospital inpatients: the Southampton Mealtime Assistance Study.” Journal of Clinical Nursing 23(21-22): 3240-3249.

    74) Roberts, H. C., Syddall, H. E., Sparkes, J., Ritchie, J., Butchart, J., Kerr, A., et al. (2014). “Grip strength and its determinants among older people in different healthcare settings.” Age & Ageing 43(2): 241-246.

    75) Simmonds, S. J., Syddall, H. E., Walsh, B., Evandrou, M., Dennison, E. M., Cooper, C., et al. (2014). “Understanding NHS hospital admissions in England: linkage of Hospital Episode Statistics to the Hertfordshire Cohort Study.” Age & Ageing 43(5): 653-660.

    77) Vimaleswaran, K. S., Cavadino, A., Berry, D. J., LifeLines Cohort Study Investigators, Jorde, R., Dieffenbach, A. K., et al. (2014). “Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.” The Lancet Diabetes & Endocrinology 2(9): 719-729.

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    79) Wallace, G., Judge, A., Prieto-Alhambra, D., de Vries, F., Arden, N. K. and Cooper, C. (2014). “The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement surgery.” Osteoarthritis & Cartilage 22(7): 918-927.

    80) Witham, M. D., Syddall, H. E., Dennison, E., Cooper, C., McMurdo, M. E. and Sayer, A. A. (2014). “ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study.” Age & Ageing 43(5): 661-666.

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    2013

    1) Akesson, K., Marsh, D., Mitchell, P. J., McLellan, A. R., Stenmark, J., Pierroz, D. D., et al. (2013). “Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle.” Osteoporos.Int. 24: 2135-2152.

    2) Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., et al. (2013). “Genetic markers of bone and joint health and physical capability in older adults: the HALCyon programme.” Bone 52: 278-285.

    3) Barker, D., Osmond, C., Grant, S., Thornburg, K. L., Cooper, C., Ring, S., et al. (2013). “Maternal cotyledons at birth predict blood pressure in childhood.” Placenta 34: 672-675.

    4) Barker, J., Barker, M., Fall, C., Osmond, C. and Cooper, C. (2013). “David J P Barker OBITUARIES.” BMJ 347.

    5) Baylis, D., Bartlett, D. B., Syddall, H. E., Ntani, G., Gale, C. R., Cooper, C., et al. (2013). “Immune-endocrine biomarkers as predictors of frailty and mortality: a 10-year longitudinal study in community-dwelling older people.” Age (Dordr.) 35: 963-971.

    6) Bruyere, O., Cooper, C., Pavelka, K., Rabenda, V., Buckinx, F., Beaudart, C., et al. (2013). “Changes in structure and symptoms in knee osteoarthritis and prediction of future knee replacement over 8 years.” Calcif.Tissue Int. 93: 502-507.

    7) Coggon, D., Ntani, G., Harris, E. C., Linaker, C., Van der Star, R., Cooper, C., et al. (2013). “Impact of carpal tunnel surgery according to pre-operative abnormality of sensory conduction in median nerve: a longitudinal study.” BMC Musculoskelet.Disord. 14: 241.

    8) Coggon, D., Ntani, G., Harris, E. C., Linaker, C., Van der Star, R., Cooper, C., et al. (2013). “Differences in risk factors for neurophysiologically confirmed carpal tunnel syndrome and illness with similar symptoms but normal median nerve function: a case-control study.” BMC Musculoskelet.Disord. 14: 240.

    9) Collings, P. J., Brage, S., Ridgway, C. L., Harvey, N. C., Godfrey, K. M., Inskip, H. M., et al. (2013). “Physical activity intensity, sedentary time, and body composition in preschoolers.” Am.J.Clin.Nutr. 97: 1020-1028.

    10) Compston, J., Bowring, C., Cooper, A., Cooper, C., Davies, C., Francis, R., et al. (2013). “Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013.” Maturitas 75: 392-396.

    11) Cooper, C. (2013). “David Barker (1938-2013).” Nature 502: 304.

    12) Cooper, C., Adachi, J. D., Bardin, T., Berenbaum, F., Flamion, B., Jonsson, H., et al. (2013). “How to define responders in osteoarthritis.” Curr.Med.Res.Opin. 29: 719-729.

    13) Cooper, C., Dennison, E., Edwards, M. H. and Litwic, A. (2013). “Epidemiology of osteoarthritis.” Medicographia 35: 145-151.

    14) Cooper, C., Fielding, R., Visser, M., van Loon, L. J., Rolland, Y., Orwoll, E., et al. (2013). “Tools in the assessment of sarcopenia.” Calcif.Tissue Int. 93: 201-210.

    15) Costa, A. G., Wyman, A., Siris, E. S., Watts, N. B., Silverman, S., Saag, K. G., et al. (2013). “When, Where and How Osteoporosis-Associated Fractures Occur: An Analysis from the Global Longitudinal Study of Osteoporosis in Women (GLOW).” PLoS.One. 8: e83306.

    16) Costello, P. M., Hollis, L. J., Cripps, R. L., Bearpark, N., Patel, H. P., Sayer, A. A., et al. (2013). “Lower maternal body condition during pregnancy affects skeletal muscle structure and glut-4 protein levels but not glucose tolerance in mature adult sheep.” Reprod.Sci. 20: 1144-1155.

    17) Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., et al. (2013). “Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.” Hum.Mol.Genet. 22: 2735-2747.

    18) Culliford, D., Maskell, J., Judge, A., Arden, N. K. and including Cooper, C. (2013). “A population-based survival analysis describing the association of body mass index on time to revision for total hip and knee replacements: results from the UK general practice research database.” BMJ Open. 3: e003614.

    19) den Hoad, M., Luan, J., Langenberg, C., Cooper, C., Sayer, A. A., Jameson, K., et al. (2013). “Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.” Int.J.Obes.(Lond) 37: 191-196.

    20) Denison, H. J., Dodds, R. M., Ntani, G., Cooper, R., Cooper, C., Sayer, A. A., et al. (2013). “How to get started with a systematic review in epidemiology: an introductory guide for early career researchers.” Arch.Public Health 71: 21.

    21) Denison, H. J., Syddall, H. E., Dodds, R., Martin, H. J., Finucane, F. M., Griffin, S. J., et al. (2013). “Effects of Aerobic Exercise on Muscle Strength and Physical Performance in Community-dwelling Older People from the Hertfordshire Cohort Study: A Randomized Controlled Trial (letter).” J.Am.Geriatr.Soc. 61: 1034-1036.

    22) Dennison, E. M., Dhanwal, D. K., Shaheen, S. O., Azagra, R., Reading, I., Jameson, K. A., et al. (2013). “Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study.” Arch.Osteoporos. 8: 115.

    23) Dennison, E. M., Harvey, N. C. and Cooper, C. (2013). “Programming of osteoporosis and impact on osteoporosis risk.” Clin.Obstet.Gynecol. 56: 549-555.

    24) Dhanwal, D. K. and Cooper, C. (2013). Developmental origins of osteoporosis. Postmenopausal Osteoporosis. Basic and Clinical Concepts. M. Meeta. London, JP Medical Limited: 51-60.

    25) Dhanwal, D. K., Siwach, R., Dixit, V., Mithal, A., Jameson, K. and Cooper, C. (2013). “Incidence of hip fracture in Rohtak district, North India.” Arch.Osteoporos. 8: 135.

    26) Edwards, M. H., Gregson, C. L., Patel, H. P., Jameson, K. A., Harvey, N. C., Sayer, A. A., et al. (2013). “Muscle size, strength, and physical performance and their associations with bone structure in the Hertfordshire Cohort Study.” J.Bone Miner.Res. 28: 2295-2304.

    27) Edwards, M. H., Jameson, K., Denison, H., Harvey, N. C., Sayer, A. A., Dennison, E. M., et al. (2013). “Clinical risk factors, bone density and fall history in the prediction of incident fracture among men and women.” Bone 52: 541-547.

    28) Edwards, M. H., Jameson, K. A., Denison, H., Harvey, N. C., Sayer, A. A., Dennison, E. M., et al. (2013). “The importance of fall history in fracture risk assessment (letter).” Bone 53: 598.

    29) Edwards, M. H., Moon, R. J., Harvey, N. C. and Cooper, C. (2013). Epidemiology and genetics of postmenopausal osteoporosis. In: Stovall, D.W. editor. Osteoporosis: Diagnosis and Management. Hoboken: John Wiley and Sons Inc. p1-14.

    31) Freemantle, N., Cooper, C., Diez-Perez, A., Gitlin, M., Radcliffe, H., Shepherd, S., et al. (2013). “Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis.” Osteoporos.Int. 24: 209-217.

    32) Freemantle, N., Cooper, C., Diez-Perez, A., Gitlin, M., Radcliffe, H., Shepherd, S., et al. (2013). “Response to comments on: Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis (letter).” Osteoporos.Int. 24: 1931-1932.

    33) Gale, C., Deary, I. J., Cooper, C. and Batty, G. D. (2013). “Response to letter by Bailey and Schinkel.” Pain 154: 2238.

    34) Gale, C. R., Baylis, D., Cooper, C. and Sayer, A. A. (2013). “Inflammatory markers and incident frailty in men and women: the English Longitudinal Study of Ageing.” Age (Dordr.) 35: 2493-2501.

    35) Gardner, M. P., Lightman, S., Sayer, A. A., Cooper, C., Cooper, R., Deeg, D., et al. (2013). “Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: An individual participant meta-analysis.” Psychoneuroendocrinology 38: 40-49.

    36) Gardner, M. P., Martin-Ruiz, C., Cooper, R., Hardy, R., Sayer, A. A., Cooper, C., et al. (2013). “Telomere length and physical performance at older ages: an individual participant meta-analysis.” PLoS.One. 8: e69526.

    37) Gregson, C. L., Hardcastle, S. A., Cooper, C. and Tobias, J. H. (2013). “Friend or foe: high bone mineral density on routine bone density scanning, a review of causes and management.” Rheumatology.(Oxford) 52: 968-985.

    38) Gregson, C. L., Sayers, A., Lazar, V., Steel, S., Dennison, E. M., Cooper, C., et al. (2013). “The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: Findings from a pQCT case-control study.” Bone 52: 380-388.

    39) Guillemin, F., Martinez, L., Calvert, M., Cooper, C., Ganiats, T., Gitlin, M., et al. (2013). “Fear of falling, fracture history, and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study.” Osteoporos.Int. 24: 3001-3010.

    40) Hardy, R., Cooper, R., Aihie, S. A., Ben-Shlomo, Y., Cooper, C., Deary, I. J., et al. (2013). “Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme.” PLoS.One. 8: e56483.

    41) Harvey, N. C., Cole, Z. A., Crozier, S. R., Ntani, G., Mahon, P. A., Robinson, S. M., et al. (2013). “Fetal and infant growth predict hip geometry at 6 y old: findings from the Southampton Women’s Survey.” Pediatr.Res. 74: 450-456.

    42) Harvey, N. C., Dennison, E. and Cooper, C. (2013). The epidemiology of osteoporosis fractures. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. C. Rosen. Ames USA, John Wiley & Sons: 348-356.

    43) Harvey, N. C., Javaid, M. K., Inskip, H. M., Godfrey, K. M. and Cooper, C. (2013). “Maternal vitamin D status during pregnancy and bone-mineral content in offspring.” Lancet 382: 766.

    44) Harvey, N. C., Matthews, P., Collins, R. and Cooper, C. (2013). “Osteoporosis epidemiology in UK Biobank: a unique opportunity for international researchers.” Osteoporos.Int. 24: 2903-2905.

    45) Hernlund, E., Svedbom, A., Ivergard, M., Compston, J., Cooper, C., Stenmark, J., et al. (2013). “Osteoporosis in the European Union: medical management, epidemiology and economic burden : A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA).” Arch.Osteoporos. 8: 136.

    46) Hesketh, K. R., McMinn, A. M., Griffin, S. J., Harvey, N. C., Godfrey, K. M., Inskip, H. M., et al. (2013). “Maternal awareness of young children’s physical activity: levels and cross-sectional correlates of overestimation.” BMC Public Health 13: 924.

    47) Hiligsmann, M., Cooper, C., Arden, N., Boers, M., Branco, J. C., Luisa, B. M., et al. (2013). “Health economics in the field of osteoarthritis: An Expert’s consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).” Semin.Arthritis Rheum. 43: 303-313.

    48) Hiligsmann, M., Kanis, J. A., Compston, J., Cooper, C., Flamion, B., Bergmann, P., et al. (2013). “Health technology assessment in osteoporosis.” Calcif.Tissue Int. 93: 1-14.

    49) Holroyd, C., Jagganeth, D., Cooper, C. and Harvey, N. C. (2013). Pharmacological treatment of osteoporosis. Osteoporosis. J. Reginster and O. Bruyere, Future Science Group.

    50) Holroyd, C. R., Harvey, N. C., Edwards, M. H. and Cooper, C. (2013). Environment. Oxford Textbook of Rheumatology. R. Watts, P. G. Conaghan, C. Denton et al. Oxford, Oxford University Press.

    51) Holt, R. I., Phillips, D. I., Jameson, K. A., Cooper, C., Dennison, E. M. and Peveler, R. C. (2013). “The relationship between depression, anxiety and cardiovascular disease: Findings from the Hertfordshire Cohort Study.” J.Affect.Disord. 150: 84-90.

    52) Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., et al. (2013). “New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.” Nat.Genet. 45(1): 76-82.

    53) Howles, S. A., Edwards, M. H., Cooper, C. and Thakker, R. V. (2013). “Kidney stones: a fetal origins hypothesis.” J.Bone Miner.Res. 28: 2535-2539.

    54) Ioannidis, G., Flahive, J., Pickard, L., Papaioannou, A., Chapurlat, R. D., Saag, K. G., et al. (2013). “Non-hip, non-spine fractures drive healthcare utilization following a fracture: the Global Longitudinal Study of Osteoporosis in Women (GLOW).” Osteoporos.Int. 24: 59-67.

    55) Javaid, M. K. and Cooper, C. (2013). “Commentary: Opportunities to prevent fracture are being missed.” BMJ 346: f278.

    56) Judge, A., Arden, N. K., Batra, R. N., Thomas, G., Beard, D., Javaid, M. K., et al. (2013). “The association of patient characteristics and surgical variables on symptoms of pain and function over 5 years following primary hip-replacement surgery: a prospective cohort study.” BMJ Open 3: pii: e002453.

    57) Kanis, J. A., Adachi, J. D., Cooper, C., Clark, P., Cummings, S. R., Diaz-Curiel, M., et al. (2013). “Standardising the descriptive epidemiology of osteoporosis: recommendations from the Epidemiology and Quality of Life Working Group of IOF.” Osteoporos.Int. 24: 2763-2764.

    58) Kanis, J. A., McCloskey, E. V., Johansson, H., Cooper, C., Rizzoli, R. and Reginster, J. Y. (2013). “European guidance for the diagnosis and management of osteoporosis in postmenopausal women.” Osteoporos.Int. 24: 23-57.

    59) Kaufman, J. M., Reginster, J. Y., Boonen, S., Brandi, M. L., Cooper, C., Dere, W., et al. (2013). “Treatment of osteoporosis in men.” Bone 53: 134-144.

    60) Litwic, A., Edwards, M. H., Dennison, E. M. and Cooper, C. (2013). “Epidemiology and burden of osteoarthritis.” Br.Med.Bull. 105: 185-199.

    61) Lotz, M., Martel-Pelletier, J., Christiansen, C., Brandi, M. L., Bruyere, O., Chapurlat, R., et al. (2013). “Value of biomarkers in osteoarthritis: current status and perspectives.” Ann.Rheum.Dis. 72: 1756-1763.

    62) Mithal, A., Bonjour, J. P., Boonen, S., Burckhardt, P., Degens, H., El Hajj, F. G., et al. (2013). “Impact of nutrition on muscle mass, strength, and performance in older adults.” Osteoporos.Int. 24: 1555-1566.

    63) Ntani, G., Palmer, K. T., Linaker, C., Harris, E. C., Van der Star, R., Cooper, C., et al. (2013). “Symptoms, signs and nerve conduction velocities in patients with suspected carpal tunnel syndrome.” BMC Musculoskelet.Disord. 14: 242.

    64) Okubo, H., Shaheen, S. O., Ntani, G., Jameson, K. A., Syddall, H. E., Sayer, A. A., et al. (2013). “Processed meat consumption and lung function: modification by antioxidants and smoking.” Eur.Respir.J.

    65) Patel, H. P., Syddall, H. E., Jameson, K., Robinson, S., Denison, H., Roberts, H. C., et al. (2013). “Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS).” Age Ageing 42: 378-384.

    66) Pelletier, J. P., Cooper, C., Peterfy, C., Reginster, J. Y., Brandi, M. L., Bruyere, O., et al. (2013). “What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?” Ann.Rheum.Dis. 72: 1594-1604.

    67) Peters, M. J., Broer, L., Willemen, H. L., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., et al. (2013). “Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.” Ann.Rheum.Dis. 72: 427-436.

    68) Pike, K. C., Inskip, H. M., Robinson, S. M., Cooper, C., Godfrey, K. M., Roberts, G., et al. (2013). “The relationship between maternal adiposity and infant weight gain, and childhood wheeze and atopy.” Thorax 68: 372-379.

    69) Pouwels, S., Bazelier, M. T., de Boer, A., Weber, W. E., Neef, C., Cooper, C., et al. (2013). “Risk of fracture in patients with Parkinson’s disease.” Osteoporos.Int. 24: 2283-2290.

    70) Pouwels, S., Bazelier, M. T., de Boer, A., Weber, W. E., Neef, C. K., Cooper, C., et al. (2013). “Five-year fracture risk estimation in patients with Parkinson’s disease.” Bone 56: 266-270.

    71) Pouwels, S., de Boer, A., Javaid, M. K., Hilton-Jones, D., Verschuuren, J., Cooper, C., et al. (2013). “Fracture rate in patients with myasthenia gravis: the general practice research database.” Osteoporos.Int. 24: 467-476.

    72) Prieto-Alhambra, D., Nogues, X., Javaid, M. K., Wyman, A., Arden, N. K., Azagra, R., et al. (2013). “An increased rate of falling leads to a rise in fracture risk in postmenopausal women with self-reported osteoarthritis: a prospective multinational cohort study (GLOW).” Ann.Rheum.Dis. 72: 911-917.

    73) Reginster, J. Y., Badurski, J., Bellamy, N., Bensen, W., Chapurlat, R., Chevalier, X., et al. (2013). “Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial.” Ann.Rheum.Dis. 72: 179-186.

    74) Rizzoli, R., Boonen, S., Brandi, M. L., Bruyere, O., Cooper, C., Kanis, J. A., et al. (2013). “Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).” Curr.Med.Res.Opin. 29: 305-313.

    75) Rizzoli, R., Reginster, J. Y., Arnal, J. F., Bautmans, I., Beaudart, C., Bischoff-Ferrari, H., et al. (2013). “Quality of life in sarcopenia and frailty.” Calcif.Tissue Int. 93: 101-120.

    76) Roberts, H. C., Pilgrim, A. L., Elia, M., Jackson, A. A., Cooper, C., Sayer, A. A., et al. (2013). “Southampton mealtime assistance study: design and methods.” BMC.Geriatr. 13: 5.

    77) Robinson, S., Ntani, G., Simmonds, S., Syddall, H., Dennison, E., Sayer, A. A., et al. (2013). “Type of milk feeding in infancy and health behaviours in adult life: findings from the Hertfordshire Cohort Study.” Br.J.Nutr. 109: 1114-1122.

    78) Robinson, S. M., Jameson, K. A., Syddall, H. E., Dennison, E. M., Cooper, C. and Aihie, S. A. (2013). “Clustering of lifestyle risk factors and poor physical function in older adults: the Hertfordshire cohort study.” J.Am.Geriatr.Soc. 61: 1684-1691.

    79) Sayer, A. A., Robinson, S. M., Patel, H. P., Shavlakadze, T., Cooper, C. and Grounds, M. D. (2013). “New horizons in the pathogenesis, diagnosis and management of sarcopenia (editorial).” Age Ageing 42: 145-150.

    80) Soni, A., Batra, R. N., Gwilym, S. E., Spector, T. D., Hart, D. J., Arden, N. K., et al. (2013). “Neuropathic features of joint pain: a community-based study.” Arthritis Rheum. 65: 1942-1949.

    81) Svedbom, A., Alvares, L., Cooper, C., Marsh, D. and Strom, O. (2013). “Balloon kyphoplasty compared to vertebroplasty and nonsurgical management in patients hospitalised with acute osteoporotic vertebral compression fracture: a UK cost-effectiveness analysis.” Osteoporos.Int. 24: 355-367.

    82) Svedbom, A., Hernlund, E., Ivergard, M., Compston, J., Cooper, C., Stenmark, J., et al. (2013). “Osteoporosis in the European Union: a compendium of country-specific reports.” Arch.Osteoporos. 8: 137.

    83) Tom, S. E., Adachi, J. D., Anderson, F. A., Jr., Boonen, S., Chapurlat, R. D., Compston, J. E., et al. (2013). “Frailty and fracture, disability, and falls: a multiple country study from the global longitudinal study of osteoporosis in women.” J.Am.Geriatr.Soc. 61: 327-334.

    84) Vestergaard, P., Prieto-Alhambra, D., Javaid, M. K. and Cooper, C. (2013). “Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose.” Osteoporos.Int. 24: 671-680.

    85) Vimaleswaran, K. S., Berry, D. J., Lu, C., Tikkanen, E., Pilz, S., Hiraki, L. T., et al. (2013). “Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts.” PLoS.Med. 10: e1001383.

    86) Wahl, D. A., Cooper, C., Ebeling, P. R., Eggersdorfer, M., Hilger, J., Hoffmann, K., et al. (2013). “A global representation of vitamin D status in healthy populations: reply to comment by Saadi (letter).” Arch.Osteoporos. 8: 122.

    87) Ward, K., Adams, J. E., Prentice, A., Aihie Sayer, A. and Cooper, C. (2013). A life course approach to healthy musculoskeletal ageing. A life course approach to healthy ageing. D. Kuh, C. Cooper, R. Hardy, M. Richards and Y. Ben-Shlomo. Oxford, Oxford University Press.

    88) Williams, E. L., Edwards, C. J., Cooper, C. and Oreffo, R. O. (2013). “The osteoarthritic niche and modulation of skeletal stem cell function for regenerative medicine.” J.Tissue Eng Regen.Med. 7: 589-608.

    89) Worsley, P., Warner, M., Mottram, S., Gadola, S., Veeger, H. E., Hermens, H., et al. (2013). “Motor control retraining exercises for shoulder impingement: effects on function, muscle activation, and biomechanics in young adults.” J.Shoulder.Elbow.Surg. 22: e11-e19.

    90) Yaqub, M. K., Ioannou, C., Javaid, M. K., Cooper, C., Papageorghiou, A. T. and Noble, J. A. (2013). “Fusion of 3D ultrasound images of the fetal femur improves boundary definition and volume measurement.” Fetal Diagn.Ther. 34: 158-165.

    2012

    1) Aihie Sayer, A. and Cooper, C. (2012). The developmental origins of ageing. Pathy’s Principles and Practice of Geriatric Medicine. A. J. Sinclair, J. E. Morley and B. Vellas, Wiley-Blackwell.

    2) Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., et al. (2012). “A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.” PLoS.One. 7: e29883.

    3) Avenell, A., MacLennan, G. S., Jenkinson, D. J., McPherson, G. C., McDonald, A. M., Pant, P. R., et al. (2012). “Long-Term Follow-Up for Mortality and Cancer in a Randomized Placebo-Controlled Trial of Vitamin D3 and/or Calcium (RECORD Trial).” J.Clin.Endocrinol.Metab 97: 614-622.

    4) Bartlett, D. B., Firth, C. M., Phillips, A. C., Moss, P., Baylis, D., Syddall, H., et al. (2012). “The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection.” Aging Cell 11: 912-915.

    5) Bazelier, M. T., Gallagher, A. M., van Staa, T. P., Cooper, C., Leufkens, H. G., Vestergaard, P., et al. (2012). “Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?” Pharmacoepidemiol.Drug Saf 21: 507-514.

    6) Bazelier, M. T., van Staa, T. P., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., et al. (2012). “A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis.” Neurology 79: 922-928.

    7) Bazelier, M. T., van Staa, T. P., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., et al. (2012). “Risk of fractures in patients with multiple sclerosis: a population-based cohort study.” Neurology 78: 1967-1973.

    8) Bazelier, M. T., Vestergaard, P., Gallagher, A. M., van Staa, T. P., Cooper, C., Leufkens, H. G., et al. (2012). “Risk of fracture with thiazolidinediones: disease or drugs?” Calcif.Tissue Int. 90: 450-457.

    9) Black, C., Ntani, G., Kenny, R., Tinati, T., Jarman, M., Lawrence, W., et al. (2012). “Variety and quality of healthy foods differ according to neighbourhood deprivation.” Health Place. 18: 1292-1299.

    10) Blunden, C. H., Inskip, H. M., Robinson, S. M., Cooper, C., Godfrey, K. M. and Kendrick, T. R. (2012). “Postpartum depressive symptoms: the B-vitamin link.” Ment.Health Fam.Med. 9: 5-13.

    11) Cawston, H., Maravic, M., Fardellone, P., Gauthier, A., Kanis, J. A., Compston, J., et al. (2012). “Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: estimations from a disease model.” Arch.Osteoporos. 7: 237-246.

    12) Cole, Z. A., Harvey, N. C., Kim, M., Ntani, G., Robinson, S. M., Inskip, H. M., et al. (2012). “Increased fat mass is associated with increased bone size but reduced volumetric density in pre pubertal children.” Bone 50: 562-567.

    13) Cooper, C., Dere, W., Evans, W., Kanis, J. A., Rizzoli, R., Sayer, A. A., et al. (2012). “Frailty and sarcopenia: definitions and outcome parameters.” Osteoporos.Int. 23: 1839-1848.

    14) Cooper, C., Frank, J., Leyland, A., Hardy, R., Lawlor, D. A., Wareham, N. J., et al. (2012). “Using cohort studies in lifecourse epidemiology.” Public Health 126: 190-192.

    15) Cooper, C. and Harvey, N. C. (2012). “Osteoporosis risk assessment (editorial).” BMJ 344: e4191.

    16) Cooper, C., Reginster, J. Y., Chapurlat, R., Christiansen, C., Genant, H., Bellamy, N., et al. (2012). “Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial.” Curr.Med.Res.Opin. 28: 231-239.

    17) Cooper, C., Reginster, J. Y., Cortet, B., Diaz-Curiel, M., Lorenc, R. S., Kanis, J. A., et al. (2012). “Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF).” Curr.Med.Res.Opin. 28: 475-491.

    18) Craig, P., Cooper, C., Gunnell, D., Haw, S., Lawson, K., Macintyre, S., et al. (2012). “Using natural experiments to evaluate population health interventions: new Medical Research Council guidance.” J.Epidemiol.Community Health 66: 1182-1186.

    19) Crozier, S. R., Harvey, N. C., Inskip, H. M., Godfrey, K. M., Cooper, C. and Robinson, S. M. (2012). “Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women’s Survey.” Am.J.Clin.Nutr. 96: 57-63.

    20) Culliford, D. J., Maskell, J., Kiran, A., Judge, A., Javaid, M. K., Cooper, C., et al. (2012). “The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database.” Osteoarthritis.Cartilage. 20: 519-524.

    21) Dastani, Z., Hivert, M. F., Timpson, N., Scott, R. A., Kizer, J. R., Lyytikainen, L. P., et al. (2012). “Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals.” PLoS Genetics 8(3).

    22) Denison, H. J., Jameson, K. A., Syddall, H. E., Dennison, E. M., Cooper, C., Sayer, A. A., et al. (2012). “Patterns of dietary supplement use among older men and women in the UK: findings from the Hertfordshire Cohort Study.” J.Nutr.Health Aging 16: 307-311.

    23) Denison, H. J., Simmonds, S. J., Syddall, H. E., Robinson, S. M., Dennison, E. M., Cooper, C., et al. (2012). “The Hertfordshire Cohort Study: from historical to high-tech studies of musculoskeletal ageing in men and women entering their ninth decade.” Int.J.Epidemiol. 41: 386-389.

    24) Dennison, E. M., Compston, J. E., Flahive, J., Siris, E. S., Gehlbach, S. H., Adachi, J. D., et al. (2012). “Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW).” Bone 50: 1288-1293.

    25) Diez-Perez, A., Adachi, J. D., Agnusdei, D., Bilezikian, J. P., Compston, J. E., Cummings, S. R., et al. (2012). “Treatment failure in osteoporosis.” Osteoporos.Int. 23: 2769-2774.

    26) Dodds, R., Denison, H. J., Ntani, G., Cooper, R., Cooper, C., Sayer, A. A., et al. (2012). “Birth weight and muscle strength: a systematic review and meta-analysis.” J.Nutr.Health Aging 16: 609-615.

    27) Dodds, R., Macdonald-Wallis, C., Kapasi, T., Sayer, A. A., Robinson, S., Godfrey, K., et al. (2012). “Grip strength at 4 years in relation to birth weight.” Journal of Developmental Origins of Health and Disease 3(02): 111-115.

    28) Drake, A. J., McPherson, R. C., Godfrey, K. M., Cooper, C., Lillycrop, K. A., Hanson, M. A., et al. (2012). “An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth.” Clin.Endocrinol.(Oxf) 77: 808-815.

    29) Druet, C., Stettler, N., Sharp, S., Simmons, R. K., Cooper, C., Davey, S. G., et al. (2012). “Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis.” Paediatr.Perinat.Epidemiol. 26: 19-26.

    30) Edwards, M. H. and Cooper, C. (2012). “Bone: the growing cost of fractures in Ireland.” Nat.Rev.Endocrinol. 8: 512-513.

    31) Edwards, M. H., Dennison, E. M. and Cooper, C. (2012). Lifecourse Epidemiology and Ageing. The Epidemiology of Ageing. A. B. Newman and J. A. Cauley, Springer.

    32) Edwards, M. H., Harvey, N. C., Dennison, E. M. and Cooper, C. (2012). Worldwide Epidemiology of Osteoporosis. Topics of osteoporosis and other bone diseases. R. Arinoviche and M. Arriagada, Chilean Osteoporosis Foundation.

    33) Estrada, K., Styrkarsdottir, U., Evangelou, E., Hsu, Y. H., Duncan, E. L., Ntzani, E. E., et al. (2012). “Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.” Nat.Genet. 44: 491-501.

    34) Eyre, S., Bowes, J., Diogo, D., Lee, A., Barton, A., Martin, P., et al. (2012). “High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.” Nat.Genet. 44: 1336-1340.

    35) Ferari, S., Bianchi, M. L., Eisman, J. A., Foldes, A. J., Adami, S., Wahl, D. A., et al. (2012). “Osteoporosis in young adults – pathophysiology, diagnosis and management.” Osteoporosis International 23(12): 2735-2748.

    36) Fisher, B. A., Plant, D., Lundberg, K., Charles, P., Barton, A., Venables, P. J., et al. (2012). “Heterogeneity of Anticitrullinated Peptide Antibodies and Response to Anti-Tumor Necrosis Factor Agents in Rheumatoid Arthritis.” J.Rheumatol. 39: 929-932.

    37) Fox, C. S., Liu, Y., White, C. C., Feitosa, M., Smith, A. V., Heard-Costa, N., et al. (2012). “Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.” PLoS.Genet. 8: e1002695.

    38) Gale, C. R., Deary, I. J., Cooper, C. and Batty, G. D. (2012). “Intelligence in childhood and chronic widespread pain in middle age: The National Child Development Survey.” Pain 153: 2339-2344.

    39) Gale, C. R., Dennison, E. M., Edwards, M., Sayer, A. A. and Cooper, C. (2012). “Symptoms of anxiety or depression and risk of fracture in older people: the Hertfordshire Cohort Study.” Arch.Osteoporos. 7: 59-65.

    40) Gale, C. R., Syddall, H. E., Bergman, H., Brunner, E. J., Cooper, C. and Sayer, A. A. (2012). “Close relationships and risk of frailty: the hertfordshire cohort study.” J.Am.Geriatr.Soc. 60: 390-392.

    41) Gauthier, A., Kanis, J. A., Jiang, Y., Dreinhofer, K., Martin, M., Compston, J., et al. (2012). “Burden of postmenopausal osteoporosis in Germany: estimations from a disease model.” Arch.Osteoporos. 7: 209-218.

    42) Gehlbach, S., Saag, K. G., Adachi, J. D., Hooven, F. H., Flahive, J., Boonen, S., et al. (2012). “Previous fractures at multiple sites increase the risk for subsequent fractures: the Global Longitudinal Study of Osteoporosis in Women.” J.Bone Miner.Res. 27: 645-653.

    43) Godfrey, K. M., Haugen, G., Kiserud, T., Inskip, H. M., Cooper, C., Harvey, N. C., et al. (2012). “Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development.” PLoS.One. 7: e41759.

    44) Guggina, P., Flahive, J., Hooven, F. H., Watts, N. B., Siris, E. S., Silverman, S., et al. (2012). “Characteristics associated with anti-osteoporosis medication use: Data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) USA cohort.” Bone 51: 975-980.

    45) Harvey, N., Dhanwal, D., Robinson, S., Kim, M., Inskip, H., Godfrey, K., et al. (2012). “Does maternal long chain polyunsaturated fatty acid status in pregnancy influence the bone health of children? The Southampton Women’s Survey.” Osteoporos.Int. 23: 2359-2367.

    46) Harvey, N. C., Cole, Z. A., Crozier, S. R., Kim, M., Ntani, G., Goodfellow, L., et al. (2012). “Physical activity, calcium intake and childhood bone mineral: a population-based cross-sectional study.” Osteoporos.Int. 23: 121-130.

    47) Harvey, N. C. and Cooper, C. (2012). “Vitamin D: some perspective please (editorial).” BMJ 345: e4695.

    48) Harvey, N. C., Javaid, K., Bishop, N., Kennedy, S., Papageorghiou, A. T., Fraser, R., et al. (2012). “MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. The MAVIDOS Study Group.” Trials 13: 13.

    49) Harvey, N. C., Lillycrop, K. A., Garratt, E., Sheppard, A., McLean, C., Burdge, G., et al. (2012). “Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content.” Calcif.Tissue Int. 90: 120-127.

    50) Harvey, N. C., Mahon, P. A., Kim, M., Cole, Z. A., Robinson, S. M., Javaid, K., et al. (2012). “Intrauterine growth and postnatal skeletal development: findings from the Southampton Women’s Survey.” Paediatr.Perinat.Epidemiol. 26: 34-44.

    51) Holroyd, C., Harvey, N., Dennison, E. and Cooper, C. (2012). “Epigenetic influences in the developmental origins of osteoporosis.” Osteoporos.Int. 23: 401-410.

    52) Holroyd, C. R., Harvey, N. C., Crozier, S. R., Winder, N. R., Mahon, P. A., Ntani, G., et al. (2012). “Placental size at 19 weeks predicts offspring bone mass at birth: Findings from the Southampton Women’s Survey.” Placenta 33: 623-629.

    53) Ikram, M. A., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., et al. (2012). “Common variants at 6q22 and 17q21 are associated with intracranial volume.” Nat.Genet. 44: 539-544.

    54) Inskip, H., Macdonald-Wallis, C., Kapasi, T., Robinson, S., Godfrey, K., Cooper, C., et al. (2012). “Associations between grip strength of parents and their 4-year-old children: findings from the Southampton Women’s Survey.” Paediatr.Perinat.Epidemiol. 26: 27-33.

    55) Ioannou, C., Javaid, M. K., Mahon, P., Yaqub, M. K., Harvey, N. C., Godfrey, K. M., et al. (2012). “The effect of maternal vitamin d concentration on fetal bone.” J.Clin.Endocrinol.Metab 97: E2070-E2077.

    56) Judge, A., Arden, N. K., Cooper, C., Kassim, J. M., Carr, A. J., Field, R. E., et al. (2012). “Predictors of outcomes of total knee replacement surgery.” Rheumatology.(Oxford) 51: 1804-1813.

    57) Judge, A., Javaid, M. K., Arden, N. K., Cushnaghan, J., Reading, I., Croft, P., et al. (2012). “Clinical tool to identify patients who are most likely to achieve long-term improvement in physical function after total hip arthroplasty.” Arthritis Care Res.(Hoboken.) 64: 881-889.

    58) Kanis, J. A., Oden, A., McCloskey, E. V., Johansson, H., Wahl, D. A. and Cooper, C. (2012). “A systematic review of hip fracture incidence and probability of fracture worldwide.” Osteoporos.Int. 23: 2239-2256.

    59) Kanis, J. A., Reginster, J. Y., Kaufman, J. M., Ringe, J. D., Adachi, J. D., Hiligsmann, M., et al. (2012). “A reappraisal of generic bisphosphonates in osteoporosis.” Osteoporos.Int. 23: 213-221.

    60) Kohler, J. A., Moon, R. J., Sands, R., Doherty, L. J., Taylor, P. A., Cooper, C., et al. (2012). “Selective reduction in trabecular volumetric bone mineral density during treatment for childhood acute lymphoblastic leukemia.” Bone 51: 765-770.

    61) Lalmohamed, A., de Vries, F., Bazelier, M. T., Cooper, A., van Staa, T. P., Cooper, C., et al. (2012). “Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study.” BMJ 345: e5085.

    62) Lalmohamed, A., Vestergaard, P., Cooper, C., de Boer, A., Leufkens, H. G., van Staa, T. P., et al. (2012). “Timing of stroke in patients undergoing total hip replacement and matched controls: a nationwide cohort study.” Stroke 43: 3225-3229.

    63) Lawrence, W., Keyte, J., Tinati, T., Haslam, C., Baird, J., Margetts, B., et al. (2012). “A mixed-methods investigation to explore how women living in disadvantaged areas might be supported to improve their diets.” J.Health Psychol. 17: 785-798.

    64) Lekamwasam, S., Adachi, J. D., Agnusdei, D., Bilezikian, J., Boonen, S., Borgstrom, F., et al. (2012). “A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis.” Osteoporos.Int. 23: 2257-2276.

    65) Lekamwasam, S., Adachi, J. D., Agnusdei, D., Bilezikian, J., Boonen, S., Borgstrom, F., et al. (2012). “An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis.” Arch.Osteoporos. 7: 25-30.

    66) Lewis, R. M., Cleal, J. K., Ntani, G., Crozier, S. R., Mahon, P. A., Robinson, S. M., et al. (2012). “Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass.” Bone 50: 337-342.

    67) Leyland, K. M., Hart, D. J., Javaid, M. K., Judge, A., Kiran, A., Soni, A., et al. (2012). “The natural history of radiographic knee osteoarthritis: A fourteen-year population-based cohort study.” Arthritis Rheum. 64: 2243-2251.

    68) Litwic, A., Edwards, M., Cooper, C. and Dennison, E. (2012). “Geographic differences in fractures among women.” Womens Health (Lond Engl.) 8: 673-684.

    69) O’Tierney, P. F., Lewis, R. M., McWeeney, S. K., Hanson, M. A., Inskip, H. M., Morgan, T. K., et al. (2012). “Immune response gene profiles in the term placenta depend upon maternal muscle mass.” Reprod.Sci. 19: 1041-1056.

    70) Palmer, K. T., Harris, E. C., Linaker, C., Barker, M., Lawrence, W., Cooper, C., et al. (2012). “Effectiveness of community- and workplace-based interventions to manage musculoskeletal-related sickness absence and job loss: a systematic review.” Rheumatology.(Oxford) 51: 230-242.

    71) Palmer, K. T., Harris, E. C., Linaker, C., Cooper, C. and Coggon, D. (2012). “Optimising case definitions of upper limb disorder for aetiological research and prevention: a review.” Occup.Environ.Med. 69: 71-78.

    72) Palmer, K. T., Harris, E. C., Linaker, C., Ntani, G., Cooper, C. and Coggon, D. (2012). “Optimal case definitions of upper extremity disorder for use in the clinical treatment and referral of patients.” Arthritis Care Res.(Hoboken.) 64: 573-580.

    73) Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., et al. (2012). “A genome-wide association search for type 2 diabetes genes in African Americans.” PLoS.One. 7: e29202.

    74) Patel, H. P., Cooper, C. and Sayer, A. A. (2012). Percutaneous muscle biopsy: history, methods and acceptability. Muscle biopsy. C. Sundaram, Intech.

    75) Patel, H. P., Jameson, K. A., Syddall, H. E., Martin, H. J., Stewart, C. E., Cooper, C., et al. (2012). “Developmental influences, muscle morphology, and sarcopenia in community-dwelling older men.” J.Gerontol.A Biol.Sci.Med.Sci. 67: 82-87.

    76) Patel, M. B., Makepeace, A. E., Jameson, K. A., Masterson, L. M., Holt, R. I., Swaminathan, R., et al. (2012). “Weight in infancy and adult calcium absorption as determinants of bone mineral density in adult men: the hertfordshire cohort study.” Calcif.Tissue Int. 91: 416-422.

    77) Pfeilschifter, J., Cooper, C., Watts, N. B., Flahive, J., Saag, K. G., Adachi, J. D., et al. (2012). “Regional and age-related variations in the proportions of hip fractures and major fractures among postmenopausal women: the Global Longitudinal Study of Osteoporosis in Women.” Osteoporos.Int. 23: 2179-2188.

    78) Pike, K. C., Calder, P. C., Inskip, H. M., Robinson, S. M., Roberts, G. C., Cooper, C., et al. (2012). “Maternal plasma phosphatidylcholine Fatty acids and atopy and wheeze in the offspring at age of 6 years.” Clin.Dev.Immunol. 2012: 474613.

    79) Pike, K. C., Inskip, H. M., Robinson, S., Lucas, J. S., Cooper, C., Harvey, N. C., et al. (2012). “Maternal late-pregnancy serum 25-hydroxyvitamin D in relation to childhood wheeze and atopic outcomes.” Thorax 67: 950-956.

    80) Pilgrim, A., Barker, M., Jackson, A., Ntani, G., Crozier, S., Inskip, H., et al. (2012). “Does living in a food insecure household impact on the diets and body composition of young children? Findings from the Southampton Women’s Survey.” J.Epidemiol.Community Health 66: e6.

    81) Prieto-Alhambra, D., Aviles, F. F., Judge, A., van Staa, T., Nogues, X., Arden, N. K., et al. (2012). “Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality.” Osteoporos.Int. 23: 2797-2803.

    82) Prieto-Alhambra, D., Servitja, S., Javaid, M. K., Garrigos, L., Arden, N. K., Cooper, C., et al. (2012). “Vitamin D threshold to prevent aromatase inhibitor-related bone loss: the B-ABLE prospective cohort study.” Breast Cancer Res.Treat. 133: 1159-1167.

    83) Rejnmark, L., Avenell, A., Masud, T., Anderson, F., Meyer, H. E., Sanders, K. M., et al. (2012). “Vitamin d with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin d trials.” J.Clin.Endocrinol.Metab 97: 2670-2681.

    84) Rizzoli, R., Adachi, J. D., Cooper, C., Dere, W., Devogelaer, J. P., Diez-Perez, A., et al. (2012). “Management of glucocorticoid-induced osteoporosis.” Calcif.Tissue Int. 91: 225-243.

    85) Rizzoli, R., Cooper, C., Reginster, J. Y., Abrahamsen, B., Adachi, J. D., Brandi, M. L., et al. (2012). “Antidepressant medications and osteoporosis.” Bone 51: 606-613.

    86) Roberts, H. C., Sparkes, J., Syddall, H., Butchart, J., Ritchie, J., Cooper, C., et al. (2012). “Is measuring grip strength acceptable to older people? Views from four healthcare settings.” Journal of Aging Research and Clinical Practice 1: 135-140.

    87) Roberts, H. C., Syddall, H. E., Cooper, C. and Aihie, S. A. (2012). “Is grip strength associated with length of stay in hospitalised older patients admitted for rehabilitation? Findings from the Southampton grip strength study.” Age Ageing 41: 641-646.

    88) Robinson, S., Cooper, C. and Aihie, S. A. (2012). “Nutrition and sarcopenia: a review of the evidence and implications for preventive strategies.” J.Aging Res. 2012: 510801.

    89) Robinson, S. M., Simmonds, S. J., Jameson, K. A., Syddall, H. E., Dennison, E. M., Cooper, C., et al. (2012). “Muscle strength in older community-dwelling men is related to type of milk feeding in infancy.” J.Gerontol.A Biol.Sci.Med.Sci. 67: 990-996.

    90) Roux, C., Wyman, A., Hooven, F. H., Gehlbach, S. H., Adachi, J. D., Chapurlat, R. D., et al. (2012). “Burden of non-hip, non-vertebral fractures on quality of life in postmenopausal women : The Global Longitudinal study of Osteoporosis in Women (GLOW).” Osteoporos.Int. 23: 2863-2871.

    91) Scott, R. A., Chu, A. Y., Grarup, N., Manning, A. K., Hivert, M. F., Shungin, D., et al. (2012). “No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.” Diabetes 61: 1291-1296.

    92) Shepstone, L., Fordham, R., Lenaghan, E., Harvey, I., Cooper, C., Gittoes, N., et al. (2012). “A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study.” Osteoporos.Int. 23: 2507-2515.

    93) Soni, A., Kiran, A., Hart, D. J., Leyland, K. M., Goulston, L., Cooper, C., et al. (2012). “Prevalence of reported knee pain over twelve years in a community-based cohort.” Arthritis Rheum. 64: 1145-1152.

    94) Stevens, P. J., Syddall, H. E., Patel, H. P., Martin, H. J., Cooper, C. and Aihie, S. A. (2012). “Is Grip Strength a Good Marker of Physical Performance among Community-Dwelling Older People?” J.Nutr.Health Aging 16: 769-774.

    95) Syddall, H. E., Evandrou, M., Dennison, E. M., Cooper, C. and Sayer, A. A. (2012). “Social inequalities in osteoporosis and fracture among community-dwelling older men and women: findings from the Hertfordshire cohort study.” Arch.Osteoporos. 7: 37-48.

    96) Taal, H. R., St, P. B., Thiering, E., Das, S., Mook-Kanamori, D. O., Warrington, N. M., et al. (2012). “Common variants at 12q15 and 12q24 are associated with infant head circumference.” Nat.Genet. 44: 532-538.

    97) Tandon, N., Fall, C. H., Osmond, C., Sachdev, H. P., Prabhakaran, D., Ramakrishnan, L., et al. (2012). “Growth from birth to adulthood and peak bone mass and density data from the New Delhi Birth Cohort.” Osteoporos.Int. 23: 2447-2459.

    98) Tinati, T., Lawrence, W., Ntani, G., Black, C., Cradock, S., Jarman, M., et al. (2012). “Implementation of new Healthy Conversation Skills to support lifestyle changes – what helps and what hinders? Experiences of Sure Start Children’s Centre staff.” Health Soc.Care Community 20: 430-437.

    99) Valdes, A. M., Doherty, S., Muir, K. R., Zhang, W., Maciewicz, R. A., Wheeler, M., et al. (2012). “Genetic contribution to radiographic severity in osteoarthritis of the knee.” Ann.Rheum.Dis. 71: 1537-1540.

    100) Verschuur, C. A., Dowell, A., Syddall, H. E., Ntani, G., Simmonds, S. J., Baylis, D., et al. (2012). “Markers of inflammatory status are associated with hearing threshold in older people: findings from the Hertfordshire ageing study.” Age Ageing 41: 92-97.

    101) Wahl, D. A., Cooper, C., Ebeling, P. R., Eggersdorfer, M., Hilger, J., Hoffmann, K., et al. (2012). “A global representation of vitamin D status in healthy populations.” Arch.Osteoporos. 7: 155-172.

    102) Walker-Bone, K., Palmer, K. T., Reading, I., Coggon, D. and Cooper, C. (2012). “Occupation and epicondylitis: a population-based study.” Rheumatology.(Oxford) 51: 305-310.

    103) Williams, E. L., Edwards, C. J., Cooper, C. and Oreffo, R. O. (2012). “Impact of inflammation on the osteoarthritic niche: implications for regenerative medicine.” Regen.Med. 7: 551-570.

    104) Wills, A. K., Black, S., Cooper, R., Coppack, R. J., Hardy, R., Martin, K. R., et al. (2012). “Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study.” Ann.Rheum.Dis. 71: 655-660.

    2011

    1) Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., et al. (2011). “Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme.” Aging Cell 10: 520-532.

    2) Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., et al. (2011). “ACTN3 genotype, athletic status, and life course physical capability: meta-analysis of the published literature and findings from nine studies.” Hum.Mutat. 32: 1008-1018.

    3) Alharbi, K. K., Hou, G., Chen, X. H., Gaunt, T. R., Syddall, H. E., Sayer, A. A., et al. (2011). “Population Mutation Scanning of Human GHR by meltMADGE and Identification of a Paucimorphic Variant.” Genet.Test.Mol.Biomarkers 15: 855-860.

    4) Arden, N. K., Kiran, A., Judge, A., Biant, L. C., Javaid, M. K., Murray, D. W., et al. (2011). “What is a good patient reported outcome after total hip replacement?” Osteoarthritis Cartilage 19: 155-162.

    5) Baird, J., Kurshid, M. A., Kim, M., Harvey, N., Dennison, E. and Cooper, C. (2011). “Does birthweight predict bone mass in adulthood? A systematic review and meta-analysis.” Osteoporos.Int 22: 1323-1334.

    6) Barker, J. P., Kajantie, E., Osmond, C., Thornburg, K. L. and Eriksson, J. G. (2011). “How boys grow determines how long they live.” Am.J Hum.Biol. 23: 412-416.

    7) Barker, M., Baird, J., Lawrence, W., Jarman, M., Black, C., Barnard, K., et al. (2011). “The Southampton Initiative for Health: a complex intervention to improve the diets and increase the physical activity levels of women from disadvantaged communities.” J Health Psychol 16: 178-191.

    8) Bazelier, M. T., van Staa, T., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., et al. (2011). “The risk of fracture in patients with multiple sclerosis: The UK general practice research database.” J.Bone Miner.Res. 26: 2271-2279.

    9) Birnie, K., Cooper, R., Martin, R. M., Kuh, D., Sayer, A. A., Alvarado, B. E., et al. (2011). “Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis.” PLoS.One. 6: e15564.

    10) Blank, R. D. and including Cooper, C. (2011). “Official Positions for FRAX(R) clinical regarding prior fractures from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 205-211.

    11) Blumsohn, A., Marin, F., Nickelsen, T., Brixen, K., Sigurdsson, G., Gonzalez, d. l., V, et al. (2011). “Early changes in biochemical markers of bone turnover and their relationship with bone mineral density changes after 24 months of treatment with teriparatide.” Osteoporos.Int 22: 1935-1946.

    12) Broy, S. B., Tanner, S. B. and including Cooper, C. (2011). “Official Positions for FRAX(R) clinical regarding rheumatoid arthritis from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 184-189.

    13) Cauley, J. A., El-Hajj, F. G., Arabi, A., Fujiwara, S., Ragi-Eis, S., Calderon, A., et al. (2011). “Official Positions for FRAX(R) clinical regarding international differences from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 240-262.

    14) Cauley, J. A., El-Hajj, F. G., Luckey, M. M. and including Cooper, C. (2011). “FRAX(R) International Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference.” J.Clin.Densitom. 14: 237-239.

    15) Chambers, J. C., Zhang, W., Sehmi, J., Li, X., Wass, M. N., Van der Harst, P., et al. (2011). “Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.” Nat.Genet. 43: 1131-1138.

    16) Cleal, J. K., Glazier, J. D., Ntani, G., Crozier, S. R., Day, P. E., Harvey, N. C., et al. (2011). “Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast.” J Physiol 589: 987-997.

    17) Compston, J. E., Watts, N. B., Chapurlat, R., Cooper, C., Boonen, S., Greenspan, S., et al. (2011). “Obesity Is Not Protective against Fracture in Postmenopausal Women: GLOW.” Am.J.Med. 124: 1043-1050.

    18) Cooper, C. and Arden, N. K. (2011). “Excess mortality in osteoarthritis (editorial).” BMJ 342: d1407.

    19) Cooper, C., Cole, Z. A., Holroyd, C. R., Earl, S. C., Harvey, N. C., Dennison, E. M., et al. (2011). “Secular trends in the incidence of hip and other osteoporotic fractures.” Osteoporos.Int 22: 1277-1288.

    20) Cooper, C., Mitchell, P. and Kanis, J. A. (2011). “Breaking the fragility fracture cycle (editorial).” Osteoporos.Int 22: 2049-2050.

    21) Cooper, R., Hardy, R., Aihie, S. A., Ben-Shlomo, Y., Birnie, K., Cooper, C., et al. (2011). “Age and Gender Differences in Physical Capability Levels from Mid-Life Onwards: The Harmonisation and Meta-Analysis of Data from Eight UK Cohort Studies.” PLoS.One. 6: e27899.

    22) Cooper, R., Kuh, D., Cooper, C., Gale, C. R., Lawlor, D. A., Matthews, F., et al. (2011). “Objective measures of physical capability and subsequent health: a systematic review.” Age Ageing 40: 14-23.

    23) Dennison, E. and Cooper, C. (2011). “Osteoporosis in 2010: building bones and (safely) preventing breaks.” Nat.Rev.Rheumatol 7: 80-82.

    24) Dennison, E. M. and Cooper, C. (2011). “Where now with NICE? (editorial).” Osteoporos.Int 22: 1007-1008.

    25) Dhanwal, D. K., Dennison, E. M., Harvey, N. C. and Cooper, C. (2011). “Epidemiology of hip fracture: Worldwide geographic variation.” Indian J Orthop. 45: 15-22.

    26) Diez-Perez, A., Hooven, F. H., Adachi, J. D., Adami, S., Anderson, F. A., Boonen, S., et al. (2011). “Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW).” Bone 49: 493-498.

    27) Dimai, H. P., Chandran, M. and including Cooper, C. (2011). “Official Positions for FRAX(R) clinical regarding smoking from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 190-193.

    28) Duncan, E. L., Danoy, P., Kemp, J. P., Leo, P. J., McCloskey, E., Nicholson, G. C., et al. (2011). “Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.” PLoS.Genet. 7: e1001372.

    29) Fisk, C. M., Crozier, S. R., Inskip, H. M., Godfrey, K. M., Cooper, C., Roberts, G. C., et al. (2011). “Breastfeeding and reported morbidity during infancy: findings from the Southampton Women’s Survey.” Matern.Child Nutr. 7: 61-70.

    30) Fisk, C. M., Crozier, S. R., Inskip, H. M., Godfrey, K. M., Cooper, C. and Robinson, S. M. (2011). “Influences on the quality of young children’s diets: the importance of maternal food choices.” Br.J Nutr. 105: 287-296.

    31) Gale, C. R., Dennison, E. M., Cooper, C. and Sayer, A. A. (2011). “Neighbourhood environment and positive mental health in older people: The Hertfordshire Cohort Study.” Health Place. 17: 867-874.

    32) Gale, C. R., Sayer, A. A., Cooper, C., Dennison, E. M., Starr, J. M., Whalley, L. J., et al. (2011). “Factors associated with symptoms of anxiety and depression in five cohorts of community-based older people: the HALCyon (Healthy Ageing across the Life Course) Programme.” Psychol.Med. 41: 2057-2073.

    33) Gauthier, A., Kanis, J. A., Martin, M., Compston, J., Borgstrom, F., Cooper, C., et al. (2011). “Development and validation of a disease model for postmenopausal osteoporosis.” Osteoporos.Int 22: 771-780.

    34) Godfrey, K. M., Sheppard, A., Gluckman, P. D., Lillycrop, K. A., Burdge, G. C., McLean, C., et al. (2011). “Epigenetic Gene Promoter Methylation at Birth Is Associated With Child’s Later Adiposity.” Diabetes 60: 1528-1534.

    35) Hans, D. B., Kanis, J. A., Baim, S., Bilezikian, J. P., Binkley, N., Cauley, J. A., et al. (2011). “Joint Official Positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX((R)). Executive Summary of the 2010 Position Development Conference on Interpretation and use of FRAX(R) in clinical practice.” J.Clin.Densitom. 14: 171-180.

    36) Harvey, N. C., Inskip, H. M., Godfrey, K. M. and Cooper, C. (2011). “Similar maternal and paternal relationships with offspring bone mass do not exclude an intrauterine mechanism: evidence from Southampton Women’s Survey.” Osteoporos.Int. 22: 2899-2900.

    37) Holroyd, C. R., Cooper, C. and Harvey, N. C. (2011). “Vitamin D and the postmenopausal population.” Menopause.Int. 17: 102-107.

    38) Javaid, M. K., Eriksson, J. G., Kajantie, E., Forsen, T., Osmond, C., Barker, D. J., et al. (2011). “Growth in childhood predicts hip fracture risk in later life.” Osteoporos.Int 22: 69-73.

    39) Javaid, M. K., Prieto-Alhambra, D., Lui, L. Y., Cawthon, P., Arden, N. K., Lang, T., et al. (2011). “Self-reported weight at birth predicts measures of femoral size but not volumetric BMD in eldery men: MrOS.” J.Bone Miner.Res. 26: 1802-1807.

    40) Jordan, J. M., Sowers, M. F., Messier, S. P., Bradley, J., Arangio, G., Katz, J. N., et al. (2011). “Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis.” Osteoarthritis Cartilage 19: 500-508.

    41) Judge, A., Cooper, C., Arden, N. K., Williams, S., Hobbs, N., Dixon, D., et al. (2011). “Pre-operative expectation predicts 12-month post-operative outcome among patients undergoing primary total hip replacement in European orthopaedic centres.” Osteoarthritis Cartilage 19: 659-667.

    42) Kanis, J. A., Cooper, C., Hiligsmann, M., Rabenda, V., Reginster, J. Y. and Rizzoli, R. (2011). “Partial adherence: a new perspective on health economic assessment in osteoporosis.” Osteoporos.Int. 22: 2565-2573.

    43) Kanis, J. A., Hans, D., Cooper, C., Baim, S., Bilezikian, J. P., Binkley, N., et al. (2011). “Interpretation and use of FRAX in clinical practice.” Osteoporos.Int. 22: 2395-2411.

    44) Kerkhof, H. J., Doherty, M., Arden, N. K., Abramson, S. B., Attur, M., Bos, S. D., et al. (2011). “Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis.” Osteoarthritis Cartilage 19: 265-271.

    45) Kerkhof, H. J., Meulenbelt, I., Akune, T., Arden, N. K., Aromaa, A., Bierma-Zeinstra, S. M., et al. (2011). “Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium.” Osteoarthritis Cartilage 19: 254-264.

    46) Kilpelainen, T. O., den, H. M., Ong, K. K., Grontved, A., Brage, S., Jameson, K., et al. (2011). “Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals.” Am.J Clin Nutr. 93: 851-860.

    47) Lanham, S. A., Bertram, C., Cooper, C. and Oreffo, R. O. (2011). “Animal models of maternal nutrition and altered offspring bone structure – Bone development across the lifecourse.” Eur.Cell Mater. 22: 321-332.

    48) Lanham, S. A., Fowden, A. L., Roberts, C., Cooper, C., Oreffo, R. O. and Forhead, A. J. (2011). “Effects of hypothyroidism on the structure and mechanical properties of bone in the ovine fetus.” J.Endocrinol. 210: 189-198.

    49) Lanham-New, S. A., Buttriss, J. L., Miles, L. M., Ashwell, M., Berry, J. L., Boucher, B. J., et al. (2011). “Proceedings of the Rank Forum on Vitamin D.” Br.J Nutr. 105: 144-156.

    50) Lawrence, W., Schlotz, W., Crozier, S., Skinner, T. C., Haslam, C., Robinson, S., et al. (2011). “Specific psychological variables predict quality of diet in women of lower, but not higher, educational attainment.” Appetite 56: 46-52.

    51) Leib, E. S., Saag, K. G., Adachi, J. D., Geusens, P. P., Binkley, N., McCloskey, E. V., et al. (2011). “Official Positions for FRAX((R)) clinical regarding glucocorticoids: the impact of the use of glucocorticoids on the estimate by FRAX((R)) of the 10 year risk of fracture from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX((R)).” J.Clin.Densitom. 14: 212-219.

    52) Lewiecki, E. M., Compston, J. E., Miller, P. D., Adachi, J. D., Adams, J. E., Leslie, W. D., et al. (2011). “FRAX((R)) Bone Mineral Density Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference.” J.Clin.Densitom. 14: 223-225.

    53) Lewiecki, E. M., Compston, J. E., Miller, P. D., Adachi, J. D., Adams, J. E., Leslie, W. D., et al. (2011). “Official Positions for FRAX(R) Bone Mineral Density and FRAX(R) simplification from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 226-236.

    54) Linaker, C., Harris, E. C., Cooper, C., Coggon, D. and Palmer, K. T. (2011). “The burden of sickness absence from musculoskeletal causes in Great Britain.” Occup.Med.(Lond) 61: 458-464.

    55) Marsh, D., Akesson, K., Beaton, D. E., Bogoch, E. R., Boonen, S., Brandi, M. L., et al. (2011). “Coordinator-based systems for secondary prevention in fragility fracture patients.” Osteoporos.Int. 22: 2051-2065.

    56) Martin, H., Aihie, S. A., Jameson, K., Syddall, H., Dennison, E. M., Cooper, C., et al. (2011). “Does diet influence physical performance in community-dwelling older people? Findings from the Hertfordshire Cohort Study.” Age Ageing 40: 181-186.

    57) Masud, T., Binkley, N., Boonen, S., Hannan, M. T. and including Cooper, C. (2011). “Official Positions for FRAX(R) clinical regarding falls and frailty: can falls and frailty be used in FRAX(R)? From Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 194-204.

    58) McCloskey, E. V., Binkley, N. and including Cooper, C. (2011). “FRAX((R)) Clinical Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference.” J.Clin.Densitom. 14: 181-183.

    59) McCloskey, E. V., Vasikaran, S. and Cooper, C. (2011). “Official Positions for FRAX(R) clinical regarding biochemical markers from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R).” J.Clin.Densitom. 14: 220-222.

    60) Mishra, G. D., Gale, C. R., Sayer, A. A., Cooper, C., Dennison, E. M., Whalley, L. J., et al. (2011). “How useful are the SF-36 sub-scales in older people? Mokken scaling of data from the HALCyon programme.” Qual.Life Res. 20: 1005-1010.

    61) Muraki, S., Dennison, E., Jameson, K., Boucher, B. J., Akune, T., Yoshimura, N., et al. (2011). “Association of vitamin D status with knee pain and radiographic knee osteoarthritis.” Osteoarthritis.Cartilage. 19: 1301-1306.

    62) Palmer, K., Coggon, D., Cooper, C., Harris, E. C. and Linaker, C. (2011). Improving the diagnostic criteria for work-related upper limb disorders for use in prevention and patient care. HSE Contract Research Report 869/2011. Sudbury.

    63) Patel, H., Syddall, H. E., Martin, H. J., Cooper, C., Stewart, C. and Sayer, A. A. (2011). “The feasibility and acceptability of muscle biopsy in epidemiological studies: findings from the Hertfordshire sarcopenia study (HSS).” J Nutr.Health Aging 15: 10-15.

    64) Pazianas, M., Cooper, C., Wang, Y., Lange, J. L. and Russell, R. G. (2011). “Atrial fibrillation and the use of oral bisphosphonates.” Ther.Clin Risk Manag. 7: 131-144.

    65) Pouwels, S., Lalmohamed, A., Souverein, P., Cooper, C., Veldt, B. J., Leufkens, H. G., et al. (2011). “Use of proton pump inhibitors and risk of hip/femur fracture: a population-based case-control study.” Osteoporos.Int 22: 903-910.

    66) Prieto-Alhambra, D., Javaid, M. K., Judge, A., Maskell, J., Kiran, A., Cooper, C., et al. (2011). “Bisphosphonate use and risk of post-operative fracture among patients undergoing a total knee replacement for knee osteoarthritis: a propensity score analysis.” Osteoporos.Int 22: 1555-1571.

    67) Prieto-Alhambra, D., Javaid, M. K., Judge, A., Maskell, J., Kiran, A., de Vries, F., et al. (2011). “Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use.” Arthritis Rheum. 63: 992-1001.

    68) Prieto-Alhambra, D., Javaid, M. K., Judge, A., Murray, D., Carr, A., Cooper, C., et al. (2011). “Association between bisphosphonate use and implant survival after primary total arthroplasty of the knee or hip: population based retrospective cohort study.” BMJ 343: d7222.

    69) Prieto-Alhambra, D., Javaid, M. K., Maskell, J., Judge, A., Nevitt, M., Cooper, C., et al. (2011). “Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study.” Ann.Rheum.Dis. 70: 134-138.

    70) Rizzoli, R., Akesson, K., Bouxsein, M., Kanis, J. A., Napoli, N., Papapoulos, S., et al. (2011). “Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.” Osteoporos.Int 22: 373-390.

    71) Rizzoli, R., Reginster, J. Y., Boonen, S., Breart, G., Diez-Perez, A., Felsenberg, D., et al. (2011). “Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis.” Calcif.Tissue Int. 89: 91-104.

    72) Roberts, H. C., Denison, H. J., Martin, H. J., Patel, H. P., Syddall, H., Cooper, C., et al. (2011). “A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach.” Age Ageing 40: 423-429.

    73) Roux, C., Cooper, C., ez-Perez, A., Martinez, L., Ortolani, S., Gitlin, M., et al. (2011). “Prevalence of osteoporosis and fractures among women prescribed osteoporosis medication in five European countries: the POSSIBLE EU((R)) study.” Osteoporos.Int 22: 1227-1236.

    74) Sambrook, P. N., Flahive, J., Hooven, F. H., Boonen, S., Chapurlat, R., Lindsay, R., et al. (2011). “Predicting fractures in an international cohort using risk factor algorithms without BMD.” J.Bone Miner.Res. 26: 2770-2777.

    75) Shaheen, S. O., Jameson, K. A., Robinson, S. M., Boucher, B. J., Syddall, H. E., Aihie, S. A., et al. (2011). “Relationship of vitamin D status to adult lung function and COPD.” Thorax 66: 692-698.

    76) Siris, E. S., Gehlbach, S., Adachi, J. D., Boonen, S., Chapurlat, R. D., Compston, J. E., et al. (2011). “Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW).” Osteoporos.Int 22: 27-35.

    77) Soler, A. M., Loth, D. W., Wain, L. V., Gharib, S. A., Obeidat, M., Tang, W., et al. (2011). “Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.” Nat.Genet. 43: 1082-1090.

    78) Soler, A. M., Wain, L. V., Repapi, E., Obeidat, M., Sayers, I., Burton, P. R., et al. (2011). “Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function.” Am.J.Respir.Crit Care Med. 184: 786-795.

    79) Speliotes, E. K., Yerges-Armstrong, L. M., Wu, J., Hernaez, R., Kim, L. J., Palmer, C. D., et al. (2011). “Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.” PLoS.Genet. 7: e1001324.

    80) Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., et al. (2011). “Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes.” Diabetes 60: 2624-2634.

    81) Valdes, A. M., Arden, N. K., Vaughn, F. L., Doherty, S. A., Leaverton, P. E., Zhang, W., et al. (2011). “Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.” Arthritis Care Res.(Hoboken.) 63: 440-444.

    82) Valdes, A. M., De Wilde, G., Doherty, S. A., Lories, R. J., Vaughn, F. L., Laslett, L. L., et al. (2011). “The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis.” Ann.Rheum.Dis. 70: 1556-1561.

    83) Valdes, A. M., Evangelou, E., Kerkhof, H. J., Tamm, A., Doherty, S. A., Kisand, K., et al. (2011). “The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance (letter).” Ann.Rheum.Dis. 70: 873-875.

    84) Valdes, A. M., Styrkarsdottir, U., Doherty, M., Morris, D. L., Mangino, M., Tamm, A., et al. (2011). “Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations.” PLoS.One. 6: e23371.

    85) Varanasi, S. S., Tuck, S. P., Mastana, S. S., Dennison, E., Cooper, C., Vila, J., et al. (2011). “Lack of association of bone morphogenetic protein 2 gene haplotypes with bone mineral density, bone loss, or risk of fractures in men.” J.Osteoporos. 2011: 243465.

    86) Vasikaran, S., Cooper, C., Eastell, R., Griesmacher, A., Morris, H. A., Trenti, T., et al. (2011). “International Osteoporosis Foundation and International Federation of Clinical Chemistry and Laboratory Medicine Position on bone marker standards in osteoporosis.” Clin.Chem.Lab Med. 49: 1271-1274.

    87) Vasikaran, S., Eastell, R., Bruyere, O., Foldes, A. J., Garnero, P., Griesmacher, A., et al. (2011). “Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards.” Osteoporos.Int 22: 391-420.

    88) Vasikaran, S. D., Cooper, C. and Kanis, J. A. (2011). “Recommendations for bone marker standards in osteoporosis: what, why and where to now? (editorial).” Ann.Clin Biochem. 48: 91-92.

    89) Vasikaran, S. D., Morris, H. A., Cooper, C. and Kanis, J. A. (2011). “Standardising biochemical assessment of bone turnover in osteoporosis (editorial).” Clin.Biochem. 44: 1033-1034.

    90) Wahl, D. A., Cooper, C. and Boonen, S. (2011). “Clinicians need to treat underlying osteoporosis (letter).” BMJ 343: d5040.

    91) Williams, F. M., Popham, M., Hart, D. J., de Schepper, E., Bierma-Zeinstra, S., Hofman, A., et al. (2011). “GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women.” Arthritis Rheum. 63: 708-712.

    92) Zhu, H., Shyh-Chang, N., Segre, A. V., Shinoda, G., Shah, S. P., Einhorn, W. S., et al. (2011). “The Lin28/let-7 axis regulates glucose metabolism.” Cell 147: 81-94.

    2010

    1) Abrahamsen, B., Masud, T., Avenell, A., Anderson, F., Meyer, H. E., Cooper, C., et al. (2010). “Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europexen,K.;.” BMJ 340: b5463.

    2) Adachi, J. D., Adami, S., Gehlbach, S., Anderson, F. A., Jr., Boonen, S., Chapurlat, R. D., et al. (2010). “Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women.” Mayo Clin Proc. 85: 806-813.

    3) Adams, J., Mullee, M., Burridge, J., Hammond, A. and Cooper, C. (2010). “Responsiveness of self-report and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis.” Arthritis Care Res.(Hoboken.) 62: 274-278.

    4) Ashfield, T. A., Syddall, H. E., Martin, H. J., Dennison, E. M., Cooper, C. and Aihie, S. A. (2010). “Grip strength and cardiovascular drug use in older people: findings from the Hertfordshire Cohort Study.” Age Ageing 39: 185-191.

    5) Breart, G., Cooper, C., Meyer, O., Speirs, C., Deltour, N. and Reginster, J. Y. (2010). “Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database.” Osteoporos.Int 21: 1181-1187.

    6) Cooper, C. (2010). “Osteoporosis: disease severity and consequent fracture management.” Osteoporos.Int 21 Suppl 2: S425-S429.

    7) Cooper, C. (2010). “Osteoporosis research thrives: IOF WCO-ECCEO10.” Expert.Rev.Pharmacoecon.Outcomes.Res. 10: 367-370.

    8) Cooper, C., Goodfellow, L., Harvey, N., Earl, S., Holroyd, C., Cole, Z., et al. (2010). Placental function and later risk of osteoporosis. The placenta and human developmental programming. G. J. Burton, D. J. P. Barker, A. Moffett and K. Thornburg, Cambridge University Press.

    9) Cooper, C., Steinbuch, M., Stevenson, R., Miday, R. and Watts, N. B. (2010). “The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK.” Osteoporos.Int 21: 569-577.

    10) Cooper, R., Kuh, D., Hardy, R. and Mortality Review Group (including Cooper, C., Aihie Sayer,A.,Gale,C.R.,Syddall,H.E.) (2010). “Objectively measured physical capability levels and mortality: systematic review and meta-analysis.” BMJ 341: c4467.

    11) Crozier, S. R., Inskip, H. M., Barker, M. E., Lawrence, W. T., Cooper, C. and Robinson, S. M. (2010). “Development of a 20-item food frequency questionnaire to assess a ‘prudent’ dietary pattern among young women in Southampton.” Eur.J Clin Nutr. 64: 99-104.

    12) Crozier, S. R., Inskip, H. M., Godfrey, K. M., Cooper, C., Harvey, N. C., Cole, Z. A., et al. (2010). “Weight gain in pregnancy and childhood body composition: findings from the Southampton Women’s Survey.” Am.J Clin Nutr. 91: 1745-1751.

    13) De Lucia, R. E., Sleigh, A., Finucane, F. M., Brage, S., Stolk, R. P., Cooper, C., et al. (2010). “Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.” Obesity.(Silver.Spring) 18: 625-631.

    14) Dennison, E. M., Cooper, C. and Cole, Z. A. (2010). “Early development and osteoporosis and bone health.” Journal of Developmental Origins of Health and Disease 1: 142-149.

    15) Dennison, E. M., Jameson, K. A., Syddall, H. E., Martin, H. J., Cushnaghan, J., Aihie, S. A., et al. (2010). “Bone health and deterioration in quality of life among participants from the Hertfordshire cohort study.” Osteoporos.Int 21: 1817-1824.

    16) Dhanwal, D. K., Cooper, C. and Dennison, E. M. (2010). “Geographic variation in osteoporotic hip fracture incidence: the growing importance of asian influences in coming decades.” J Osteoporos. 2010: 757102.

    17) Dhanwal, D. K., Kochupillai, N., Gupta, N., Cooper, C. and Dennison, E. M. (2010). “Hypovitaminosis D and bone mineral metabolism and bone density in hyperthyroidism.” J Clin Densitom. 13: 462-466.

    18) Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., et al. (2010). “New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.” Nat.Genet. 42: 105-116.

    19) Earl, S., Cole, Z. A., Holroyd, C., Cooper, C. and Harvey, N. C. (2010). “Session 2: Other diseases: Dietary management of osteoporosis throughout the life course.” Proc.Nutr.Soc. 69: 25-33.

    20) Finucane, F. M., Sharp, S. J., Purslow, L. R., Horton, K., Horton, J., Savage, D. B., et al. (2010). “The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial.” Diabetologia 53: 624-631.

    21) Freemantle, N., Cooper, C., Roux, C., Diez-Perez, A., Guillemin, F., Jonsson, B., et al. (2010). “Baseline observations from the POSSIBLE EU(R) study: characteristics of postmenopausal women receiving bone loss medications.” Arch.Osteoporos. 5: 61-72.

    22) Gale, C. R., Allerhand, M., Sayer, A. A., Cooper, C., Dennison, E. M., Starr, J. M., et al. (2010). “The structure of the Hospital Anxiety and Depression Scale in four cohorts of community-based, healthy older people: the HALCyon program.” Int Psychogeriatr. 22: 559-571.

    23) Gale, C. R., Marriott, L. D., Martyn, C. N., Limond, J., Inskip, H. M., Godfrey, K. M., et al. (2010). “Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood.” Arch.Dis.Child 95: 174-179.

    24) Goodfellow, L. R., Earl, S., Cooper, C. and Harvey, N. C. (2010). “Maternal diet, behaviour and offspring skeletal health.” International Journal of Environmental Research and Public Health 7(4): 1760-1772.

    25) Harvey, N., Dennison, E. and Cooper, C. (2010). “Osteoporosis: impact on health and economics.” Nat.Rev.Rheumatol 6: 99-105.

    26) Harvey, N. C., Javaid, M. K., Arden, N. K., Poole, J. R., Crozier, S. R., Robinson, S. M., et al. (2010). “Maternal predictors of neonatal bone size and geometry: the Southampton Women’s Survey.” Journal of Developmental Origins of Health and Disease 1: 35-41.

    27) Harvey, N. C., Mahon, P. A., Robinson, S. M., Nisbet, C. E., Javaid, M. K., Crozier, S. R., et al. (2010). “Different indices of fetal growth predict bone size and volumetric density at 4 years of age.” J Bone Miner.Res. 25: 920-927.

    28) Hassan, B., Maxwell, J. R., Hyrich, K. L., Barton, A., Worthington, J., Isaacs, J. D., et al. (2010). “Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.” Rheumatology (Oxford) 49: 43-47.

    29) Holroyd, C. R., Davies, J. H., Taylor, P., Jameson, K., Rivett, C., Cooper, C., et al. (2010). “Reduced cortical bone density with normal trabecular bone density in girls with Turner syndrome.” Osteoporos.Int 21: 2093-2099.

    30) Ingelsson, E., Langenberg, C., Hivert, M. F., Prokopenko, I., Lyssenko, V., Dupuis, J., et al. (2010). “Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.” Diabetes 59: 1266-1275.

    31) Judge, A., Cooper, C., Williams, S., Dreinhoefer, K. and Dieppe, P. (2010). “Patient-reported outcomes one year after primary hip replacement in a European Collaborative Cohort.” Arthritis Care Res.(Hoboken.) 62: 480-488.

    32) Langston, A. L., Campbell, M. K., Fraser, W. D., MacLennan, G. S., Selby, P. L., Ralston, S. H., et al. (2010). “Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget’s disease of bone.” J Bone Miner.Res. 25: 20-31.

    33) Lewiecki, E. M., Cooper, C., Thompson, E., Hartl, F., Mehta, D. and Papapoulos, S. E. (2010). “Ibandronate does not increase risk of atrial fibrillation in analysis of pivotal clinical trials.” Int J Clin Pract. 64: 821-826.

    34) Lewis, R. M., Greenwood, S. L., Cleal, J. K., Crozier, S. R., Verrall, L., Inskip, H. M., et al. (2010). “Maternal muscle mass may influence system A activity in human placenta.” Placenta 31: 418-422.

    35) Lips, P., Jameson, K., Bianchi, M. L., Goemaere, S., Boonen, S., Reeve, J., et al. (2010). “Validation of the IOF quality of life questionnaire for patients with wrist fracture.” Osteoporos.Int 21: 61-70.

    36) Lyritis, G., Marin, F., Barker, C., Pfeifer, M., Farrerons, J., Brixen, K., et al. (2010). “Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS.” Curr.Med.Res.Opin. 26: 1799-1807.

    37) Mahon, P., Harvey, N., Crozier, S., Inskip, H., Robinson, S., Arden, N., et al. (2010). “Low maternal vitamin D status and fetal bone development: cohort study.” J Bone Miner.Res. 25: 14-19.

    38) McCloskey, E., Compston, J. and Cooper, C. (2010). “The US FRAX filter: avoiding confusion or hindering progress? (letter).” Osteoporos.Int 21: 885.

    39) Nettleton, J. A., McKeown, N. M., Kanoni, S., Lemaitre, R. N., Hivert, M. F., Ngwa, J., et al. (2010). “Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies.” Diabetes Care 33: 2684-2691.

    40) Palmer, K. and Cooper, C. (2010). Repeated movements and repeated trauma affecting the musculoskeletal system. Hunter’s Diseases of Occupations. P. Baxter, A. Tar-Ching, A. Cockcroft, P. Durrington and M. Harrington. London, Hodder Arnold Publishers Ltd: 687-712.

    41) Patel, H. P., Syddall, H. E., Martin, H. J., Stewart, C. E., Cooper, C. and Sayer, A. A. (2010). “Hertfordshire sarcopenia study: design and methods.” BMC.Geriatr. 10: 43.

    42) Pazianas, M., Cooper, C., Ebetino, F. H. and Russell, R. G. (2010). “Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis.” Ther.Clin Risk Manag. 6: 325-343.

    43) Pouwels, S., Lalmohamed, A., Leufkens, H. G., de Boer, A., Cooper, C., van Staa, T., et al. (2010). “Risk of fracture and bone mineral density in stroke response (letter).” Stroke 41(1): E60.

    44) Pouwels, S., Lalmohamed, A., van Staa, T., Cooper, C., Souverein, P., Leufkens, H. G., et al. (2010). “Use of organic nitrates and the risk of hip fracture: a population-based case-control study.” J Clin Endocrinol.Metab 95: 1924-1931.

    45) Price, A. J., Longino, D., Rees, J., Rout, R., Pandit, H., Javaid, K., et al. (2010). “Are pain and function better measures of outcome than revision rates after TKR in the younger patient?” Knee. 17: 196-199.

    46) Repapi, E., Sayers, I., Wain, L. V., Burton, P. R., Johnson, T., Obeidat, M., et al. (2010). “Genome-wide association study identifies five loci associated with lung function.” Nat.Genet. 42: 36-44.

    47) Saxena, R., Hivert, M. F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., et al. (2010). “Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.” Nat.Genet. 42: 142-148.

    48) Sayer, A. A., Stewart, C., Patel, H. and Cooper, C. (2010). “The developmental origins of sarcopenia: from epidemiological evidence to underlying mechanisms.” Journal of Developmental Origins of Health and Disease 1(3): 150-157.

    49) Shaheen, S. O., Jameson, K. A., Syddall, H. E., Aihie, S. A., Dennison, E. M., Cooper, C., et al. (2010). “The relationship of dietary patterns with adult lung function and COPD.” Eur.Respir.J 36: 277-284.

    50) Strom, O., Leonard, C., Marsh, D. and Cooper, C. (2010). “Cost-effectiveness of balloon kyphoplasty in patients with symptomatic vertebral compression fractures in a UK setting.” Osteoporos.Int 21: 1599-1608.

    51) Syddall, H., Roberts, H. C., Evandrou, M., Cooper, C., Bergman, H. and Aihie, S. A. (2010). “Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study.” Age Ageing 39: 197-203.

    52) Syddall, H. E., Simmonds, S. J., Martin, H. J., Watson, C., Dennison, E. M., Cooper, C., et al. (2010). “Cohort profile: The Hertfordshire Ageing Study (HAS).” Int J Epidemiol. 39: 36-43.

    53) Szopa, M., Meirhaeghe, A., Luan, J., Moreno, L. A., Gonzalez-Gross, M., Vidal-Puig, A., et al. (2010). “No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits.” Am.J Clin Nutr. 92: 252-257.

    54) Valdes, A. M., Arden, N. K., Tamm, A., Kisand, K., Doherty, S., Pola, E., et al. (2010). “A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis.” Osteoarthritis.Cartilage. 18: 699-704.

    55) Valdes, A. M., McWilliams, D., Arden, N. K., Doherty, S. A., Wheeler, M., Muir, K. R., et al. (2010). “Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes.” Arthritis Rheum. 62: 2688-2695.

    56) Valdes, A. M., Spector, T. D., Tamm, A., Kisand, K., Doherty, S. A., Dennison, E. M., et al. (2010). “Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis.” Arthritis Rheum. 62: 2347-2352.

    57) Wang, T. J., Zhang, F., Richards, J. B., Kestenbaum, B., van Meurs, J. B., Berry, D., et al. (2010). “Common genetic determinants of vitamin D insufficiency: a genome-wide association study.” Lancet 376: 180-188.

    2009

    1) Abdin-Mohamed, M., Jameson, K., Dennison, E. M., Cooper, C. and Arden, N. K. (2009). “Volumetric bone mineral density of the tibia is not increased in subjects with radiographic knee osteoarthritis.” Osteoarthritis.Cartilage. 17(2): 174-177.

    2) Abrahamsen, B., van Staa, T., Ariely, R., Olson, M. and Cooper, C. (2009). “Excess mortality following hip fracture: a systematic epidemiological review.” Osteoporos.Int. 20: 1633-1650.

    3) Baird, J., Cooper, C., Margetts, B. M., Barker, M. and Inskip, H. M. (2009). “Changing health behaviour of young women from disadvantaged backgrounds: evidence from systematic reviews.” Proc.Nutr.Soc. 68: 195-204.

    4) Barker, M., Lawrence, W., Crozier, S., Robinson, S., Baird, J., Margetts, B., et al. (2009). “Educational attainment, perceived control and the quality of women’s diets.” Appetite 52: 631-636.

    5) Boonen, S., Kay, R., Cooper, C., Haentjens, P., Vanderschueren, D., Callewaert, F., et al. (2009). “Osteoporosis management: a perspective based on bisphosphonate data from randomised clinical trials and observational databases.” Int J Clin Pract. 63: 1792-1804.

    6) Cole, Z. A., Dennison, E. M. and Cooper, C. (2009). “The impact of methods for estimating bone health and the global burden of bone disease.” Salud Publica Mex. 51 Suppl 1: S38-S45.

    7) Cole, Z. A., Gale, C. R., Javaid, M. K., Robinson, S. M., Law, C., Boucher, B. J., et al. (2009). “Maternal dietary patterns during pregnancy and childhood bone mass: a longitudinal study.” J.Bone Miner.Res. 24: 663-668.

    8) Compston, J., Cooper, A., Cooper, C., Francis, R., Kanis, J. A., Marsh, D., et al. (2009). “Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK.” Maturitas 62: 105-108.

    9) Cooper, C., Aihie Sayer, A., Mishra, G. and Kuh, D. (2009). Developmental origins of musculoskeletal disease. Early life origins of human health and disease. J. P. Newnham and M. G. Ros. Basel, Karger: 100-112.

    10) Cooper, C., Harvey, N., Cole, Z., Hanson, M. and Dennison, E. (2009). “Developmental origins of osteoporosis: the role of maternal nutrition.” Adv.Exp.Med.Biol. 646: 31-39.

    11) Cooper, C., Rizzoli, R. and Reginster, J. Y. (2009). “The International Osteoporosis Foundation: history, objectives and achievements.” Osteoporos.Int. 20 Suppl 3: S241-S242.

    12) Cooper, C., Westlake, S., Harvey, N. and Dennison, E. (2009). “Developmental origins of osteoporotic fracture.” Adv.Exp.Med.Biol. 639: 217-236.

    13) Cranney, A., Wells, G. A., Yetisir, E., Adami, S., Cooper, C., Delmas, P. D., et al. (2009). “Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data.” Osteoporos.Int 20(2): 291-297.

    14) Crozier, S. R., Robinson, S. M., Borland, S. E., Godfrey, K. M., Cooper, C. and Inskip, H. M. (2009). “Do women change their health behaviours in pregnancy? Findings from the Southampton Women’s Survey.” Paediatr.Perinat.Epidemiol. 23: 446-453.

    15) Crozier, S. R., Robinson, S. M., Godfrey, K. M., Cooper, C. and Inskip, H. M. (2009). “Women’s dietary patterns change little from before to during pregnancy.” J.Nutr. 139: 1956-1963.

    16) Cushnaghan, J., Bennett, J., Reading, I., Croft, P., Byng, P., Cox, K., et al. (2009). “Long-term outcome following total knee arthroplasty: a controlled longitudinal study.” Ann.Rheum.Dis. 68: 642-647.

    17) de Vries, F., Cooper, A. L., Cockle, S. M., van Staa, T. P. and Cooper, C. (2009). “Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates.” Osteoporos.Int 20: 1989-1998.

    18) Dennison, E. M., Holroyd, C. R. and Cooper, C. (2009). Quality of Life and Bone Health. Health-Related Quality of Life. E. C. Hoffman, Nova Science: 133-142.

    19) Dennison, E. M., Syddall, H. E., Jameson, K. A., Sayer, A. A., Gaunt, T. R., Rodriguez, S., et al. (2009). “A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study.” J.Rheumatol. 36: 1520-1526.

    20) Finucane, F. M., Horton, J., Purslow, L. R., Savage, D. B., Brage, S., Besson, H., et al. (2009). “Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial.” BMC.Endocr.Disord. 9: 15.

    21) Gale, C. R., Batty, G. D., Cooper, C. and Deary, I. J. (2009). “Psychomotor coordination and intelligence in childhood and health in adulthood–testing the system integrity hypothesis.” Psychosom.Med. 71: 675-681.

    22) Gale, C. R., Martyn, C. N., Marriott, L. D., Limond, J., Crozier, S., Inskip, H. M., et al. (2009). “Dietary patterns in infancy and cognitive and neuropsychological function in childhood.” J.Child Psychol.Psychiatry 50: 816-823.

    23) Harvey, N. C., Robinson, S. M., Crozier, S. R., Marriott, L. D., Gale, C. R., Cole, Z. A., et al. (2009). “Breast-feeding and adherence to infant feeding guidelines do not influence bone mass at age 4 years.” Br.J.Nutr. 102: 915-920.

    24) Holt, R. I., Phillips, D. I., Jameson, K. A., Cooper, C., Dennison, E. M. and Peveler, R. C. (2009). “The relationship between depression and diabetes mellitus: findings from the Hertfordshire Cohort Study.” Diabet.Med. 26: 641-648.

    25) Hooven, F. H., Adachi, J. D., Adami, S., Boonen, S., Compston, J., Cooper, C., et al. (2009). “The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design.” Osteoporos.Int. 20: 1107-1116.

    26) Inskip, H. M., Crozier, S. R., Godfrey, K. M., Borland, S. E., Cooper, C. and Robinson, S. M. (2009). “Women’s compliance with nutrition and lifestyle recommendations before pregnancy: general population cohort study.” BMJ 338: b481.

    27) Lam, S. C., Allen, R., Pearson, G. and Cooper, C. (2009). “Parametric characterization of spinal motions in osteoporotic vertebral fracture at level T12 with fluoroscopy.” Med.Eng Phys. 31: 346-355.

    28) Lawrence, W., Skinner, T. C., Haslam, C., Robinson, S., Inskip, H., Barker, D., et al. (2009). “Why women of lower educational attainment struggle to make healthier food choices: the importance of psychological and social factors.” Psychology and Health 24(9): 1003-1020.

    29) Lindgren, C. M., Heid, I. M., Randall, J. C., Lamina, C., Steinthorsdottir, V., Qi, L., et al. (2009). “Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.” PLoS.Genet. 5: e1000508.

    30) Liu, B., Balkwill, A., Cooper, C., Roddam, A., Brown, A. and Beral, V. (2009). “Reproductive history, hormonal factors and the incidence of hip and knee replacement for osteoarthritis in middle-aged women.” Ann.Rheum.Dis. 68: 1165-1170.

    31) Mahon, P. A., Cooper, C., Crozier, S. R. and Godfrey, K. M. (2009). “The use of 3D ultrasound to investigate fetal bone development.” Norwegian Journal of Epidemiology 19: 45-52.

    32) Martin, H. J., Syddall, H. E., Dennison, E. M., Cooper, C. and Sayer, A. A. (2009). “Physical performance and physical activity in older people: are developmental influences important?” Gerontology 55: 186-193.

    33) McMinn, A. M., van Sluijs, E. M., Harvey, N. C., Cooper, C., Inskip, H. M., Godfrey, K. M., et al. (2009). “Validation of a maternal questionnaire on correlates of physical activity in preschool children.” Int J Behav.Nutr.Phys.Act. 6: 81.

    34) Pouwels, S., Lalmohamed, A., Leufkens, B., de Boer, A., Cooper, C., van Staa, T., et al. (2009). “Risk of hip/femur fracture after stroke: a population-based case-control study.” Stroke 40: 3281-3285.

    35) Pouwels, S., van Staa, T. P., Egberts, A. C., Leufkens, H. G., Cooper, C. and de Vries, F. (2009). “Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study.” Osteoporos.Int. 20: 1499-1506.

    36) Reid, D. M., Devogelaer, J. P., Saag, K., Roux, C., Lau, C. S., Reginster, J. Y., et al. (2009). “Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial.” Lancet 373: 1253-1263.

    37) Robinson, S., Syddall, H., Jameson, K., Batelaan, S., Martin, H., Dennison, E. M., et al. (2009). “Current patterns of diet in community-dwelling older men and women: results from the Hertfordshire Cohort Study.” Age Ageing 38: 594-599.

    38) Robinson, S. M., Marriott, L. D., Crozier, S. R., Harvey, N. C., Gale, C. R., Inskip, H. M., et al. (2009). “Variations in infant feeding practice are associated with body composition in childhood: a prospective cohort study.” J.Clin.Endocrinol.Metab 94: 2799-2805.

    39) Syddall, H., Evandrou, M., Cooper, C. and Sayer, A. A. (2009). “Social inequalities in grip strength, physical function, and falls among community dwelling older men and women: findings from the Hertfordshire Cohort Study.” J.Aging Health 21: 913-939.

    40) Syddall, H. E., Martin, H. J., Harwood, R. H., Cooper, C. and Aihie, S. A. (2009). “The SF-36: a Simple, Effective Measure of Mobility-Disability for Epidemiological Studies.” J.Nutr.Health Aging 13: 57-62.

    41) van den Brand, M. W., Samson, M. M., Pouwels, S., van Staa, T. P., Thio, B., Cooper, C., et al. (2009). “Use of anti-depressants and the risk of fracture of the hip or femur.” Osteoporos.Int. 20: 1705-1713.

    42) van Staa, T. P. and Cooper, C. (2009). Glucocorticoids and bone. Atlas of osteoporosis. E. Orwoll. New York, Springer: 91-98.

    43) Willer, C. J., Speliotes, E. K., Loos, R. J., Li, S., Lindgren, C. M., Heid, I. M., et al. (2009). “Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.” Nat.Genet. 41: 25-34.

    44) Williams, E. L., Harvey, N., Dennison, E., Edwards, C. and Cooper, C. (2009). “Maternal nutrition and bone health in the offspring.” Int J Clin Rheumatol 4: 133-145.

    45) Winsloe, C., Earl, S., Dennison, E. M., Cooper, C. and Harvey, N. C. (2009). “Early life factors in the pathogenesis of osteoporosis.” Curr.Osteoporos.Rep. 7: 140-144.

    2008

    1) Adams, J., Burridge, J., Mullee, M., Hammond, A. and Cooper, C. (2008). “The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial.” Rheumatology.(Oxford) 47: 1548-1553.

    2) Ashwell, M., Stone, E., Mathers, J., Barnes, S., Compston, J., Francis, R. M., et al. (2008). “Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy?” Br.J Nutr. 99(1): 198-205.

    3) Baird, J., Poole, J., Robinson, S., Marriott, L., Godfrey, K., Cooper, C., et al. (2008). “Milk feeding and dietary patterns predict weight and fat gains in infancy.” Paediatr.Perinat.Epidemiol 22: 575-586.

    4) Barker, M., Lawrence, W. T., Skinner, T. C., Haslam, C. O., Robinson, S. M., Inskip, H. M., et al. (2008). “Constraints on food choices of women in the UK with lower educational attainment.” Public Health Nutr. 11: 1229-1237.

    5) Batty, G. D., Smith, G. D., Cooper, C. and Gale, C. R. (2008). “Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33,261 individuals from the Hertfordshire studies.” Eur.J Cardiovasc.Prev.Rehabil. 15: 494-496.

    6) Boonen, S., Marin, F., Obermayer-Pietsch, B., Simoes, M. E., Barker, C., Glass, E. V., et al. (2008). “Effects of previous antiresorptive therapy on the bone mineral density response to two years of teriparatide treatment in postmenopausal women with osteoporosis.” J Clin.Endocrinol Metab 93: 852-860.

    7) Bruyere, O., Burlet, N., Delmas, P. D., Rizzoli, R., Cooper, C. and Reginster, J. Y. (2008). “Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.” BMC.Musculoskelet.Disord. 9: 165.

    8) Cole, Z., Dennison, E. and Cooper, C. (2008). “Update on the treatment of post-menopausal osteoporosis.” Br.Med Bull. 86: 129-143.

    9) Cole, Z. A., Dennison, E. M. and Cooper, C. (2008). “Osteoporosis epidemiology update.” Curr.Rheumatol.Rep. 10: 92-96.

    10) Cooper, C., Harvey, N., Javaid, K., Hanson, M. and Dennison, E. (2008). “Growth and bone development.” Nestle.Nutr.Workshop Ser.Pediatr.Program. 61: 53-68.

    11) Cooper, C., Jakob, F., Chinn, C., Martin-Mola, E., Fardellone, P., Adami, S., et al. (2008). “Fracture incidence and changes in quality of life in women with an inadequate clinical outcome from osteoporosis therapy: the Observational Study of Severe Osteoporosis (OSSO).” Osteoporos.Int 19: 493-501.

    12) Costello, P. M., Rowlerson, A., Astaman, N. A., Anthony, F. E., Sayer, A. A., Cooper, C., et al. (2008). “Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development.” J Physiol 586: 2371-2379.

    13) Cox, H., Puffer, S., Morton, V., Cooper, C., Hodson, J., Masud, T., et al. (2008). “Educating nursing home staff on fracture prevention: a cluster randomised trial.” Age Ageing 37: 167-172.

    14) Dunn, N., Inskip, H., Kendrick, A., Oestmann, A., Barnett, J., Godfrey, K., et al. (2008). “Does perceived financial strain predict depression among young women? Longitudinal findings from the Southampton Women’s Survey.” Mental Health in Family Medicine 5: 15-21.

    15) Earl, S., Cooper, C. and Arden, N. (2008). “Osteoarthritis: ‘programming’ by the early environment.” Rheumatology in Practice 6: 4-7.

    16) Fawcett, K. A., Grimsey, N., Loos, R. J., Wheeler, E., Daly, A., Soos, M., et al. (2008). “Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations.” Diabetes 57: 2527-2533.

    17) Gale, C. R., Robinson, S. M., Harvey, N. C., Javaid, M. K., Jiang, B., Martyn, C. N., et al. (2008). “Maternal vitamin D status during pregnancy and child outcomes.” Eur.J Clin.Nutr. 62(1): 68-77.

    18) Gluckman, P. D., Hanson, M. A., Cooper, C. and Thornburg, K. L. (2008). “Effect of in utero and early-life conditions on adult health and disease.” N.Engl.J Med 359: 61-73.

    19) Harvey, N., Dennison, E. and Cooper, C. (2008). Epidemiology of osteoporotic fractures. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. C. Rosen. Washington, American Society for Bone and Mineral Research: 198-203.

    20) Harvey, N. C., Dennison, E. M. and Cooper, C. (2008). “The importance of vitamin D in pregnancy and childhood (editorial).” National Knowledge Week on Osteoporosis.

    21) Harvey, N. C., Javaid, M. K., Poole, J. R., Taylor, P., Robinson, S. M., Inskip, H. M., et al. (2008). “Paternal skeletal size predicts intrauterine bone mineral accrual.” J Clin.Endocrinol Metab 93: 1676-1681.

    22) Holroyd, C., Cooper, C. and Dennison, E. (2008). “Epidemiology of osteoporosis.” Best.Pract.Res.Clin.Endocrinol Metab 22: 671-685.

    23) Holroyd, C., Rajagopal, V., Cooper, C. and Dennison, E. M. (2008). Osteoporosis Risk Assessment. Handbook on Osteoporosis. R. Keen and G. Clunie. Oxford, Oxford University Press.

    24) Inskip, H. M., Dunn, N., Godfrey, K. M., Cooper, C. and Kendrick, T. (2008). “Is birth weight associated with risk of depressive symptoms in young women? Evidence from the Southampton Women’s Survey.” Am J Epidemiol 167(2): 164-168.

    25) Kanis, J. A., Adams, J., Borgstrom, F., Cooper, C., Jonsson, B., Preedy, D., et al. (2008). “The cost-effectiveness of alendronate in the management of osteoporosis.” Bone 42(1): 4-15.

    26) Kanis, J. A., Adams, J., Borgstrom, F., Cooper, C., Jonsson, B., Preedy, D., et al. (2008). “Modelling cost-effectiveness in osteoporosis.” Bone 43: 215-216.

    27) Kanis, J. A., Burlet, N., Cooper, C., Delmas, P. D., Reginster, J. Y., Borgstrom, F., et al. (2008). “European guidance for the diagnosis and management of osteoporosis in postmenopausal women.” Osteoporos.Int. 19(4): 399-428.

    28) Kanis, J. A., Compston, J. E. and including Cooper, C. (2008). “NICE continues to muddy the waters of osteoporosis.” Osteoporos.Int 19: 1105-1107.

    29) Kanis, J. A., McCloskey, E. V., Johansson, H., Strom, O., Borgstrom, F., Oden, A., et al. (2008). “Case finding for the management of osteoporosis with FRAX–assessment and intervention thresholds for the UK.” Osteoporos.Int 19: 1395-1408.

    30) Kendrick, T., Dunn, N., Robinson, S., Oestmann, A., Godfrey, K., Cooper, C., et al. (2008). “A longitudinal study of blood folate levels and depressive symptoms among young women in the Southampton Women’s Survey.” J Epidemiol Community Health 62: 966-972.

    31) Langdahl, B. L., Uitterlinden, A. G., Ralston, S. H., Trikalinos, T. A., Balcells, S., Brandi, M. L., et al. (2008). “Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.” Bone 42: 969-981.

    32) Lanham, S. A., Roberts, C., Cooper, C. and Oreffo, R. O. (2008). “Intrauterine programming of bone. Part 1: Alteration of the osteogenic environment.” Osteoporos.Int. 19(2): 147-156.

    33) Lanham, S. A., Roberts, C., Perry, M. J., Cooper, C. and Oreffo, R. O. (2008). “Intrauterine programming of bone. Part 2: Alteration of skeletal structure.” Osteoporos.Int. 19(2): 157-167.

    34) Lewiecki, E. M., Bilezikian, J. P., Cooper, C., Hochberg, M. C., Luckey, M. M., Maricic, M., et al. (2008). “Proceedings of the eighth annual santa fe bone symposium, august 3-4, 2007.” J Clin.Densitom. 11: 313-324.

    35) Loos, R. J., Lindgren, C. M., Li, S., Wheeler, E., Zhao, J. H., Prokopenko, I., et al. (2008). “Common variants near MC4R are associated with fat mass, weight and risk of obesity.” Nat.Genet. 40: 768-775.

    36) Martin, H. J., Syddall, H. E., Dennison, E. M., Cooper, C. and Sayer, A. A. (2008). “Relationship between customary physical activity, muscle strength and physical performance in older men and women: findings from the Hertfordshire Cohort Study.” Age Ageing 37: 589-593.

    37) Martin, H. J., Syddall, H. E., Dennison, E. M., Cox, V. A., Cooper, C. and Aihie Sayer, A. (2008). “Assessing Physical Activity in Older People: Findings from the Hertfordshire Cohort Study.” The Open Geriatric Medicine Journal 1: 43-49.

    38) Moinuddin, M. M., Jameson, K. A., Syddall, H. E., Sayer, A. A., Martin, H. J., Robinson, S., et al. (2008). “Cigarette smoking, birthweight and osteoporosis in adulthood: results from the hertfordshire cohort study.” Open.Rheumatol.J 2: 33-37.

    39) Obermayer-Pietsch, B. M., Marin, F., McCloskey, E. V., Hadji, P., Farrerons, J., Boonen, S., et al. (2008). “Effects of two years of daily teriparatide treatment on BMD in postmenopausal women with severe osteoporosis with and without prior antiresorptive treatment.” J Bone Miner.Res. 23: 1591-1600.

    40) Phillips, D. I., Syddall, H. E., Cooper, C. and Hanson, M. A. (2008). “Association of adult height and leg length with fasting plasma cortisol concentrations: evidence for an effect of normal variation in adrenocortical activity on growth.” Am J Hum.Biol. 20: 712-715.

    41) Rajagopal, V., Holroyd, C., Cooper, C. and Dennison, E. M. (2008). Epidemiology of Osteoporotic Fracture. Handbook on Osteoporosis. R. Keen and G. Clunie. Oxford, Oxford University Press.

    42) Robinson, S. M., Jameson, K. A., Batelaan, S. F., Martin, H. J., Syddall, H. E., Dennison, E. M., et al. (2008). “Diet and its relationship with grip strength in community-dwelling older men and women: the Hertfordshire cohort study.” J Am Geriatr.Soc. 56(1): 84-90.

    43) Sayer, A. A., Dennison, E. M., Syddall, H. E., Jameson, K., Martin, H. J. and Cooper, C. (2008). “The developmental origins of sarcopenia: using peripheral quantitative computed tomography to assess muscle size in older people.” J Gerontol.A Biol.Sci Med Sci 63: 835-840.

    44) Sayer, A. A., Syddall, H., Martin, H., Patel, H., Baylis, D. and Cooper, C. (2008). “The developmental origins of sarcopenia.” J Nutr.Health Aging 12: 427-432.

    45) Scott-Russell, A., Dennison, E., Taylor, P. and Cooper, C. (2008). “Comment on: Comparing morphometric X-ray absorptiometry and radiography in defining vertebral wedge fractures in patients with ankylosing spondylitis.” Rheumatology.(Oxford) 47: 1107-1108.

    46) Thomas, S. L., Edwards, C. J., Smeeth, L., Cooper, C. and Hall, A. J. (2008). “How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database?” Arthritis Rheum. 59: 1314-1321.

    47) Ugboma, I., Syddall, H. E., Cox, V., Cooper, C., Briggs, R. and Aihie Sayer, A. (2008). “Coding geriatric syndromes: how good are we?” CME Journal Geriatric Medicine 10: 34-36.

    48) van Meurs, J. B., Trikalinos, T. A., Ralston, S. H., Balcells, S., Brandi, M. L., Brixen, K., et al. (2008). “Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.” JAMA 299: 1277-1290.

    49) van Staa, T. P., Cooper, C., Barlow, D. and Leufkens, H. G. (2008). “Individualizing the risks and benefits of postmenopausal hormone therapy.” Menopause. 15: 374-381.

    50) von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gotzsche, P. C., Vandenbroucke, J. P., et al. (2008). “[The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies].” Rev.Esp.Salud Publica 82: 251-259.

    2007

    1) Abdollahi, M. R., Lewis, R. M., Gaunt, T. R., Cumming, D. V., Rodriguez, S., Rose-Zerilli, M., et al. (2007). “Quantitated transcript haplotypes (QTH) of AGTR1, reduced abundance of mRNA haplotypes containing 1166C (rs5186:A>C), and relevance to metabolic syndrome traits.” Hum.Mutat. 28: 365-373.

    2) Aihie Sayer, A. and Cooper, C. (2007). “Aging, sarcopenia and the life course.” Rev.Clin.Gerontol. 16: 265-274.

    3) Alharbi, K. K., Spanakis, E., Tan, K., Smith, M. J., Aldahmesh, M. A., O’Dell, S. D., et al. (2007). “Prevalence and functionality of paucimorphic and private MC4R mutations in a large, unselected European British population, scanned by meltMADGE.” Hum.Mutat. 28: 294-302.

    4) Batty, G. D., Smith, G. D., Fall, C. H., Sayer, A. A., Dennison, E., Cooper, C., et al. (2007). “Association of diarrhoea in childhood with blood pressure and coronary heart disease in older age: analyses of two UK cohort studies.” Int.J Epidemiol 36(6): 1349-1355.

    5) Cole, Z. A. and Cooper, C. (2007). “Bone modeling: the first step in the bone-building process.” Medicographia 29: 113-119.

    6) Cooper, C. (2007). Bone and its characteristics in postmenopausal women. The living skeleton. C. Roux, Wolters Kluwer Health: 61-77.

    7) Cushnaghan, J., Coggon, D., Reading, I., Croft, P., Byng, P., Cox, K., et al. (2007). “Long-term outcome following total hip arthroplasty: A controlled longitudinal study.” Arthritis Rheum. 57(8): 1375-1380.

    8) de Vries, F., Pouwels, S., Lammers, J. W., Leufkens, H. G., Bracke, M., Cooper, C., et al. (2007). “Use of inhaled and oral glucocorticoids, severity of inflammatory disease and risk of hip/femur fracture: a population-based case-control study.” J Intern.Med 261: 170-177.

    9) de Vries, F., Souverein, P. C., Cooper, C., Leufkens, H. G. and van Staa, T. P. (2007). “Use of beta-Blockers and the Risk of Hip/Femur Fracture in the United Kingdom and The Netherlands.” Calcif.Tissue Int 80: 69-75.

    10) Dennison, E. and Cooper, C. (2007). Lifestyle and constitutional risk factors. S. Lanham-New, T. O’Neill, R. Morris, D. Skelton and A. Sutcliffe. London, Atlas Medical Publishing: 69-80.

    11) Dennison, E. M., Syddall, H. E., Aihie Sayer, A., Martin, H. J. and Cooper, C. (2007). “Lipid profile, obesity and bone mineral density: the Hertfordshire Cohort Study.” QJM. 100: 297-303.

    12) Edwards, C. J., Cooper, C., Fisher, D., Field, M., van Staa, T. P. and Arden, N. K. (2007). “The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis.” Arthritis Rheum. 57(7): 1151-1157.

    13) Edwards, C. J., Syddall, H., Goswami, R., Goswami, P., Dennison, E. M., Arden, N. K., et al. (2007). “The autoantibody rheumatoid factor may be an independent risk factor for ischaemic heart disease in men.” Heart 93(10): 1263-1267.

    14) de Vries, F., Bracke, M., Leufkens, H. G., Lammers, J. W., Cooper, C. and van Staa, T. P. (2007). “Fracture risk with intermittent high-dose oral glucocorticoid therapy.” Arthritis Rheum. 56(1): 208-214.

    15) de Vries, F., Pouwels, S., Bracke, M., Leufkens, H. G., Cooper, C., Lammers, J. W., et al. (2007). “Use of beta-2 agonists and risk of hip/femur fracture: a population-based case-control study.” Pharmacoepidemiol.Drug Saf 16(6): 612-619.

    16) Gale, C. R., Javaid, M. K., Robinson, S. M., Law, C. M., Godfrey, K. M. and Cooper, C. (2007). “Maternal size in pregnancy and body composition in children.” J Clin.Endocrinol.Metab 92(10): 3904-3911.

    17) Gale, C. R., Martyn, C. N., Cooper, C. and Sayer, A. A. (2007). “Grip strength, body composition, and mortality.” Int.J Epidemiol. 36(1): 228-235.

    18) Harvey, N. C., Poole, J. R., Javaid, M. K., Dennison, E. M., Robinson, S., Inskip, H. M., et al. (2007). “Parental determinants of neonatal body composition.” J Clin Endocrinol.Metab 92: 523-526.

    19) Inskip, H. M., Godfrey, K. M., Martin, H. J., Simmonds, S. J., Cooper, C. and Aihie Sayer, A. (2007). “Size at birth and its relation to muscle strength in young adult women.” J Intern.Med. 262(3): 368-374.

    20) Kanis, J. A., Oden, A., Johnell, O., Johansson, H., De Laet, C., Brown, J., et al. (2007). “The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women.” Osteoporos.Int. 18(8): 1033-1046.

    21) Lips, M. A., Syddall, H. E., Gaunt, T. R., Rodriguez, S., Day, I. N., Cooper, C., et al. (2007). “Interaction between birthweight and polymorphism in the calcium-sensing receptor gene in determination of adult bone mass: the hertfordshire cohort study.” J Rheumatol. 34: 769-775.

    22) Liu, B., Balkwill, A., Banks, E., Cooper, C., Green, J. and Beral, V. (2007). “Relationship of height, weight and body mass index to the risk of hip and knee replacements in middle-aged women.” Rheumatology.(Oxford) 46: 861-867.

    23) Martin, R., Harvey, N. C., Crozier, S. R., Poole, J. R., Javaid, M. K., Dennison, E. M., et al. (2007). “Placental calcium transporter (PMCA3) gene expression predicts intrauterine bone mineral accrual.” Bone 40: 1203-1208.

    24) Oliver, H., Jameson, K. A., Sayer, A. A., Cooper, C. and Dennison, E. M. (2007). “Growth in early life predicts bone strength in late adulthood: The Hertfordshire Cohort Study.” Bone 41(3): 400-405.

    25) Pain, H., Gale, C. R., Watson, C., Cox, V., Cooper, C. and Sayer, A. A. (2007). “Readiness of elders to use assistive devices to maintain their independence in the home.” Age Ageing 36(4): 465-467.

    26) Robinson, S., Marriott, L., Poole, J., Crozier, S., Borland, S., Lawrence, W., et al. (2007). “Dietary patterns in infancy: the importance of maternal and family influences on feeding practice.” Br.J Nutr. 98: 1029-1037.

    27) Sayer, A. A., Syddall, H. E., Dennison, E. M., Martin, H. J., Phillips, D. I., Cooper, C., et al. (2007). “Grip strength and the metabolic syndrome: findings from the Hertfordshire Cohort Study.” QJM. 100(11): 707-713.

    28) Schlotz, W., Ambery, P., Syddall, H. E., Crozier, S. R., Sayer, A. A., Cooper, C., et al. (2007). “Specific associations of insulin resistance with impaired health-related quality of life in the Hertfordshire Cohort Study.” Qual.Life Res. 16(3): 429-436.

    29) Seeman, E., Compston, J., Adachi, J., Brandi, M. L., Cooper, C., wson-Hughes, B., et al. (2007). “Non-compliance: the Achilles’ heel of anti-fracture efficacy.” Osteoporos.Int. 18(6): 711-719.

    30) Smith, H., Anderson, F., Raphael, H., Maslin, P., Crozier, S. and Cooper, C. (2007). “Effect of annual intramuscular vitamin D on fracture risk in elderly men and women–a population-based, randomized, double-blind, placebo-controlled trial.” Rheumatology.(Oxford) 46(12): 1852-1857.

    31) van Schoor, N. M., Dennison, E., Lips, P., Uitterlinden, A. G. and Cooper, C. (2007). “Serum fasting cortisol in relation to bone, and the role of genetic variations in the glucocorticoid receptor.” Clin.Endocrinol.(Oxf) 67(6): 871-878.

    32) van Staa, T. P., Geusens, P., Zhang, B., Leufkens, H. G., Boonen, A. and Cooper, C. (2007). “Individual fracture risk and the cost-effectiveness of bisphosphonates in patients using oral glucocorticoids.” Rheumatology.(Oxford) 46(3): 460-466.

    33) van Staa, T. P., Kanis, J. A., Geusens, P., Boonen, A., Leufkens, H. G. and Cooper, C. (2007). “The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks.” Value.Health 10(5): 348-357.

    34) Vilarino-Guell, C., Miles, L. J., Duncan, E. L., Ralston, S. H., Compston, J. E., Cooper, C., et al. (2007). “PTHR1 polymorphisms influence BMD variation through effects on the growing skeleton.” Calcif.Tissue Int. 81(4): 270-278.

    35) Wilting, I., de Vries, F., Thio, B. M., Cooper, C., Heerdink, E. R., Leufkens, H. G., et al. (2007). “Lithium use and the risk of fractures.” Bone 40: 1252-1258.

    36) Ye, S., Patodi, N., Walker-Bone, K., Reading, I., Cooper, C. and Dennison, E. (2007). “Variation in the matrix metalloproteinase-3, -7, -12 and -13 genes is associated with functional status in rheumatoid arthritis.” Int J Immunogenet. 34: 81-85.

    2006

    1) Arden, N. and Cooper, C. (2006). Osteoarthritis handbook. London, Taylor & Francis.

    2) Arden, N. K., Crozier, S., Smith, H., Anderson, F., Edwards, C., Raphael, H., et al. (2006). “Knee pain, knee osteoarthritis, and the risk of fracture.” Arthritis Rheum. 55: 610-615.

    3) Arden, N. K., Earl, S., Fisher, D. J., Cooper, C., Carruthers, S. and Goater, M. (2006). “Persistence with teriparatide in patients with osteoporosis: the UK experience.” Osteoporos.Int 17: 1626-1629.

    4) Boonen, S., Bischoff-Ferrari, H. A., Cooper, C., Lips, P., Ljunggren, O., Meunier, P. J., et al. (2006). “Addressing the Musculoskeletal Components of Fracture Risk with Calcium and Vitamin D: A Review of the Evidence.” Calcif.Tissue Int 78: 257-270.

    5) Carr, A. J., Thompson, P. W. and Cooper, C. (2006). “Factors associated with adherence and persistence to bisphosphonate therapy in osteoporosis: a cross-sectional survey.” Osteoporos.Int 17: 1638-1644.

    6) Cooper, C. (2006). “Bone supplement: Proceedings of ECTS/IBMS Geneva 2005-06-20.” Bone 38: 2-3.

    7) Cooper, C. (2006). “Beyond daily dosing: Clinical experience.” Bone 38: S13-S17.

    8) Cooper, C., Aihie Sayer, A. and Dennison, E. M. (2006). The developmental environment: clinical perspectives on the effect on the musculoskeletal system. Developmental origins of health and disease. M. A. Hanson and P. Gluckman. Cambridge, Cambridge University Press: 392-405.

    9) Cooper, C., Harvey, N. C., Dennison, E. M. and van Staa, T. P. (2006). “Update on the Epidemiology of Paget’s Disease of Bone.” J Bone Miner.Res. 21 Suppl 2: 3-8.

    10) Cooper, C., Javaid, M., Gale, C., Dennison, E. and Godfrey, K. (2006). “Maternal vitamin D status and childhood bone mass – Authors’ reply.” Lancet 367: 1317.

    11) Cooper, C., Westlake, S., Harvey, N., Javaid, K., Dennison, E. and Hanson, M. (2006). “Review: developmental origins of osteoporotic fracture.” Osteoporos.Int 17: 337-347.

    12) Cooper, C. and Woolf, A. D. (2006). Osteoporosis: best practice and research compendium. Oxford, Elsevier.

    13) de Rooij, S. R., Painter, R. C., Roseboom, T. J., Phillips, D. I., Osmond, C., Barker, D. J., et al. (2006). “Glucose tolerance at age 58 and the decline of glucose tolerance in comparison with age 50 in people prenatally exposed to the Dutch famine.” Diabetologia 49: 637-643.

    14) de Vries, F., de Vries, C., Cooper, C., Leufkens, B. and van Staa, T. P. (2006). “Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database.” Int J Epidemiol 35: 1301-1308.

    15) Dennison, E., Medley, J. and Cooper, C. (2006). “Who is at risk of osteoporosis?” Women’s Health Medicine 3: 152-154.

    16) Dennison, E., Mohamed, M. A. and Cooper, C. (2006). “Epidemiology of osteoporosis.” Rheum.Dis.Clin North Am 32: 617-629.

    17) Dennison, E. M., Syddall, H. E., Statham, C., Aihie Sayer, A. and Cooper, C. (2006). “Relationships between SF-36 health profile and bone mineral density: the Hertfordshire Cohort Study.” Osteoporos.Int 17: 1435-1442.

    18) Edwards, C. J. and Cooper, C. (2006). “Early environmental factors and rheumatoid arthritis.” Clin Exp.Immunol. 143: 1-5.

    19) Edwards, C. J., Goswami, R., Goswami, P., Syddall, H., Dennison, E. M., Arden, N. K., et al. (2006). “Growth and infectious exposure during infancy and the risk of rheumatoid factor in adult life.” Ann.Rheum.Dis. 65: 401-404.

    20) Edwards, C. J., Syddall, H., Goswami, R., Goswami, P., Dennison, E. M. and Cooper, C. (2006). “Infections in infancy and the presence of antinuclear antibodies in adult life.” Lupus 15: 213-217.

    21) Fawcett, K. A., Wareham, N. J., Luan, J., Syddall, H., Cooper, C., O’rahilly, S., et al. (2006). “PARL Leu262Val is not associated with fasting insulin levels in UK populations.” Diabetologia 49: 2649-2652.

    22) Ganpule, A., Yajnik, C. S., Fall, C. H., Rao, S., Fisher, D. J., Kanade, A., et al. (2006). “Bone Mass in Indian Children–Relationships to Maternal Nutritional Status and Diet during Pregnancy: the Pune Maternal Nutrition Study.” J Clin Endocrinol.Metab 91: 2994-3001.

    23) Harvey, N., Earl, S. and Cooper, C. (2006). Epidemiology of osteoporotic fracture. Primer on the metabolic bone diseases and disorders of mineral metabolism. M. J. Favus, American Society for Bone and Mineral Research: 244-248.

    24) Harvey, N., Westlake, S., Dennison, E. and Cooper, C. (2006). The epidemiology of osteoporosis. Osteoporosis and the osteoporosis of rheumatic diseases. A companion to rheumatology. N. E. Lane and P. Sambrook, Mosby: 1-13.

    25) Hashimoto, J., Ohno, I., Nakatsuka, K., Yoshimura, N., Takata, S., Zamma, M., et al. (2006). “Prevalence and clinical features of Paget’s disease of bone in Japan.” J Bone Miner.Metab 24: 186-190.

    26) Inskip, H. M., Godfrey, K. M., Robinson, S. M., Law, C. M., Barker, D. J. and Cooper, C. (2006). “Cohort profile: The Southampton Women’s Survey.” Int J Epidemiol 35: 42-48.

    27) Jakob, F., Marin, F., Martin-Mola, E., Torgerson, D., Fardellone, P., Adami, S., et al. (2006). “Characterization of patients with an inadequate clinical outcome from osteoporosis therapy: the Observational Study of Severe Osteoporosis (OSSO).” QJM. 99: 531-543.

    28) Javaid, M. K., Crozier, S. R., Harvey, N. C., Gale, C. R., Dennison, E. M., Boucher, B. J., et al. (2006). “Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study.” Lancet 367: 36-43.

    29) Javaid, M. K., Lekamwasam, S., Clark, J., Dennison, E. M., Syddall, H. E., Loveridge, N., et al. (2006). “Infant growth influences proximal femoral geometry in adulthood.” J Bone Miner.Res. 21: 508-512.

    30) Jordan, K. M., Syddall, H. E., Garnero, P., Gineyts, E., Dennison, E. M., Sayer, A. A., et al. (2006). “Urinary CTX-II and glucosyl-galactosyl-pyridinoline are associated with the presence and severity of radiographic knee osteoarthritis in men.” Ann.Rheum.Dis. 65: 871-877.

    31) Kaptoge, S., Armbrecht, G., Felsenberg, D., Lunt, M., Weber, K., Boonen, S., et al. (2006). “Whom to treat? The contribution of vertebral X-rays to risk-based algorithms for fracture prediction. Results from the European Prospective Osteoporosis Study.” Osteoporos.Int 17: 1369-1381.

    32) Kerr, A., Syddall, H. E., Cooper, C., Turner, G. F., Briggs, R. S. and Sayer, A. A. (2006). “Does admission grip strength predict length of stay in hospitalised older patients?” Age Ageing 35: 82-84.

    33) Kuh, D., Hardy, R., Butterworth, S., Okell, L., Richards, M., Wadsworth, M., et al. (2006). “Developmental origins of midlife physical performance: evidence from a British birth cohort.” Am J Epidemiol 164: 110-121.

    34) Kuh, D., Hardy, R., Butterworth, S., Okell, L., Wadsworth, M., Cooper, C., et al. (2006). “Developmental origins of midlife grip strength: findings from a birth cohort study.” J Gerontol.A Biol.Sci Med Sci 61: 702-706.

    35) Martin, H. J., Yule, V., Syddall, H. E., Dennison, E. M., Cooper, C. and Aihie Sayer, A. (2006). “Is hand-held dynamometry useful for the measurement of quadriceps strength in older people? A comparison with the gold standard biodex dynamometry.” Gerontology 52: 154-159.

    36) Oreffo, R., Cooper, C., Mason, C. and Clements, M. (2006). “Mesenchymal stem cells – lineage, plasticity and skeletal therapeutic potential.” Stem Cells Reviews 1: 169-178.

    37) Palmer, K. T. and Cooper, C. (2006). “Work-related disorders of the upper limb.” Arthritis Research Campaign: Topical Reviews 10: 1-7.

    38) Poor, G., Donath, J., Fornet, B. and Cooper, C. (2006). “Epidemiology of Paget’s Disease in Europe: The Prevalence Is Decreasing.” J Bone Miner.Res. 21: 1545-1549.

    39) Reginster, J. Y., Adami, S., Lakatos, P., Greenwald, M., Stepan, J. J., Silverman, S. L., et al. (2006). “Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2 year results from the MOBILE study.” Ann.Rheum.Dis. 65: 654-661.

    40) Reginster, J. Y., Felsenberg, D., Cooper, C., Stakkestad, J. A., Miller, P. D., Kendler, D. L., et al. (2006). “A new concept for bisphosphonate therapy: a rationale for the development of monthly oral dosing of ibandronate.” Osteoporos.Int 17: 159-166.

    41) Reid, D. M., Mackay, I., Wilkinson, S., Miller, C., Schuette, D. G., Compston, J., et al. (2006). “Cross-calibration of dual-energy X-ray densitometers for a large, multi-center genetic study of osteoporosis.” Osteoporos.Int 17: 125-132.

    42) Robinson, S. M., Batelaan, S. F., Syddall, H. E., Sayer, A. A., Dennison, E. M., Martin, H. J., et al. (2006). “Combined effects of dietary fat and birth weight on serum cholesterol concentrations: the Hertfordshire Cohort Study.” Am J Clin Nutr 84: 237-244.

    43) Rodriguez, S., Huang, S., Chen, X. H., Gaunt, T. R., Syddall, H. E., Gilg, J. A., et al. (2006). “A study of TH01 and IGF2-INS-TH haplotypes in relation to smoking initiation in three independent surveys.” Pharmacogenet.Genomics 16: 15-23.

    44) Sambrook, P. and Cooper, C. (2006). “Seminar on osteoporosis. Osteoporosis: trends in epidemiology, pathogenesis and treatment.” Lancet 367: 2010-2018.

    45) Sayer, A. A., Syddall, H. E., Martin, H. J., Dennison, E. M., Anderson, F. H. and Cooper, C. (2006). “Falls, sarcopenia, and growth in early life: findings from the hertfordshire cohort study.” Am J Epidemiol 164: 665-671.

    46) Sayer, A. A., Syddall, H. E., Martin, H. J., Dennison, E. M., Roberts, H. C. and Cooper, C. (2006). “Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study.” Age Ageing 35: 409-415.

    47) Staa, T. P., Geusens, P., Bijlsma, J. W., Leufkens, H. G. and Cooper, C. (2006). “Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis.” Arthritis Rheum. 54: 3104-3112.

    48) van Schoor, N. M., Knol, D. L., Glas, C. A., Ostelo, R. W., Leplege, A., Cooper, C., et al. (2006). “Development of the Qualeffo-31, an osteoporosis-specific quality-of-life questionnaire.” Osteoporos.Int 17: 543-551.

    49) van Staa, T. P., Geusens, P., Kanis, J. A., Leufkens, H. G., Gehlbach, S. and Cooper, C. (2006). “A simple clinical score for estimating the long-term risk of fracture in post-menopausal women.” QJM. 99: 673-682.

    50) Walker-Bone, K., Reading, I., Coggon, D., Cooper, C. and Palmer, K. T. (2006). “Risk factors for specific upper limb disorders as compared with non-specific upper limb pain: assessing the utility of a structured examination schedule.” Occup.Med (Lond) 56: 243-250.

    51) Yang, X. B., Webb, D., Blaker, J., Boccaccini, A. R., Maquet, V., Cooper, C., et al. (2006). “Evaluation of human bone marrow stromal cell growth on biodegradable polymer/bioglass composites.” Biochem.Biophys.Res.Commun. 342: 1098-1107.

    52) Yoshimura, N., Kinoshita, H., Hori, N., Nishioka, T., Ryujin, M., Mantani, Y., et al. (2006). “Risk factors for knee osteoarthritis in Japanese men: a case-control study.” Mod.Rheumatol. 16: 24-29.

    2005

    1) Abdollahi, M. R., Gaunt, T. R., Syddall, H. E., Cooper, C., Phillips, D. I., Ye, S., et al. (2005). “Angiotensin II type I receptor gene polymorphism: anthropometric and metabolic syndrome traits.” J Med.Genet. 42: 396-401.

    2) Adams, J., Burridge, J., Mullee, M., Hammond, A. and Cooper, C. (2005). “Self-reported hand functional ability measured by the DASH in individuals with early rheumatoid arthritis.” Br J Hand Therapy 10: 21-24.

    3) Alharbi, K. K., Aldahmesh, M. A., Spanakis, E., Haddad, L., Whittall, R. A., Chen, X. H., et al. (2005). “Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population.” Genome Res. 15: 967-977.

    4) Arden, N. K. and Cooper, C. (2005). Osteoarthritis: epidemiology. Osteoarthritis handbook. N. Arden and C. Cooper. London, Taylor & Francis.

    5) Arden, N. K., Price, C., Reading, I., Stubbing, J., Hazelgrove, J., Dunne, C., et al. (2005). “A multicentre randomized controlled trial of epidural corticosteroid injections for sciatica: the WEST study.” Rheumatology.(Oxford) 44: 1399-1406.

    6) Arden, N. K., Syddall, H. E., Javaid, M. K., Dennison, E. M., Swaminathan, R., Fall, C., et al. (2005). “Early life influences on serum 1,25 (OH) vitamin D.” Paediatr.Perinat.Epidemiol. 19(1): 36-42.

    7) Birrell, F., Arden, N. K., Conaghan, P. G., Cooper, C., Dieppe, P. and Doherty, M. (2005). “Is it time for more rheumatologists to embrace osteoarthritis?” Rheumatology.(Oxford) 44: 829-830.

    8) Cooper, C. (2005). “Epidemiology of osteoporotic fracture: looking to the future.” Rheumatology.(Oxford) 44 Suppl 4: iv36-iv40.

    9) Cooper, C. (2005). An overview of osteoporosis epidemiology. Drug therapy for osteoporosis. M. Kleerekoper. Oxford, Taylor and Francis.

    10) Cooper, C., Gehlbach, S. H. and Lindsay, R. (2005). Prevention and treatment of osteoporosis: a clinician’s guide. London, Taylor and Francis.

    11) Cooper, C., Javaid, K., Westlake, S., Harvey, N. and Dennison, E. (2005). “Developmental origins of osteoporotic fracture: the role of maternal vitamin d insufficiency.” J Nutr 135: 2728S-2734S.

    12) Cooper, M. S., Syddall, H. E., Fall, C. H., Wood, P. J., Stewart, P. M., Cooper, C., et al. (2005). “Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study.” Clin.Endocrinol.(Oxf) 62: 692-697.

    13) de Vries, F., van Staa, T. P., Bracke, M. S., Cooper, C., Leufkens, H. G. and Lammers, J. W. (2005). “Severity of obstructive airway disease and risk of osteoporotic fracture.” Eur.Respir.J 25: 879-884.

    14) Delmas, P. D., Rizzoli, R., Cooper, C. and Reginster, J. Y. (2005). “Treatment of patients with postmenopausal osteoporosis is worthwhile. The position of the International Osteoporosis Foundation.” Osteoporos.Int. 16(1): 1-5.

    15) Dennison, E., Syddall, H., Fall, C., Brandi, M. L. and Cooper, C. (2005). “Evidence of sexual dimorphism in relationships between estrogen receptor polymorphisms and bone mass: the hertfordshire study.” J Rheumatol. 32: 2400-2404.

    16) Dennison, E. M., Syddall, H. E., Sayer, A. A., Gilbody, H. J. and Cooper, C. (2005). “Birth Weight and Weight at 1 Year Are Independent Determinants of Bone Mass in the Seventh Decade: The Hertfordshire Cohort Study.” Pediatr.Res. 57: 582-586.

    17) Edwards, C. J., Arden, N. K., Fisher, D., Saperia, J. C., Reading, I., van Staa, T. P., et al. (2005). “The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database.” Rheumatology.(Oxford) 44: 1394-1398.

    18) Grant, A. M., Avenell, A., Campbell, M. K., McDonald, A. M., MacLennan, G. S., McPherson, G. C., et al. (2005). “Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial.” Lancet 365: 1621-1628.

    19) Harvey, N. and Cooper, C. (2005). “Physiotherapy for neck and back pain.” BMJ 330: 53-54.

    20) Harvey, N. C., Dennison, E. and Cooper, C. (2005). “The epidemiology of osteoporotic fractures.” Osteoporosis Review 13: 1-5.

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