Director and Professor of Rheumatology

Cyrus Cooper is Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit at the University of Southampton, and Chair of Musculoskeletal Science at the University of Oxford. Professor Cooper graduated from the University of Cambridge and St Bartholomew’s Hospital, London in 1980, and completed his residency in 1985 at the Southampton University Hospitals. In 1990, he won an MRC Travelling Fellowship to the Mayo Clinic, USA, where he continued his research in osteoporosis. He returned to the UK in 1992 to take up a position as Senior Lecturer in Rheumatology and MRC Senior Clinical Scientist. He was promoted to the foundation Chair in Rheumatology at the University of Southampton in 1997 while continuing as an MRC Senior Clinical Scientist at the MRC Environmental Epidemiology Unit. In 2003, he was appointed Director of the MRC Epidemiology Resource Centre, University of Southampton. In 2010, this was reconfigured as the MRC Lifecourse Epidemiology Unit and quinquennial funding extended to 2015. Professor Cooper leads an internationally competitive programme of research into the epidemiology of musculoskeletal disorders, most notably osteoporosis. His key research contributions have been: 1) discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood; 2) demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood; 3) characterisation of the definition and incidence rates of vertebral fractures; 4) leadership of large pragmatic randomised controlled trials of calcium and vitamin D supplementation in the elderly as immediate preventative strategies against hip fracture.

Professor Cooper is immediate past-President of the Bone Research Society of Great Britain and Chairman of the Committee of Scientific Advisors, International Osteoporosis Foundation. He has previously served as Chairman of the National Osteoporosis Society and has worked on numerous Department of Health, European Community and World Health Organisation committees and working groups. He is Chair of the MRC Population Health Sciences Research Network; Associate Director of Research at the University of Southampton Medical School; and Associate Editor of Osteoporosis International. He has published extensively (over 450 research papers) on osteoporosis and rheumatic disorders and pioneered clinical studies on the developmental origins of peak bone mass.

1. Member, Arthritis and Rheumatism Council Research Sub-committee, 1996 - 2000
2. Chairman, Advisory Specialist Education Committee, South and West Regional Rheumatology Division, 1998-2002
3. Advisory Member, WHO Informal Consultation on Osteoporosis: a Global Strategy for Osteoporosis Management and Prevention, 1998-2002
4. Chair, Scientific Advisory Board, National Osteoporosis Society, 1998-2001
5. MRC Representative, British Medical Association, Medical Academic Staff Committee, 1996-2004
6. Advisory Committee on Distinction Awards, South East Region, 2000-2004
7. Chairman, ARC Clinical Trials Committee, 2001-2006
8. Director of Research, University of Southampton Medical School, 2002-2005
9. Professional Practice Committee, American Society for Bone and Mineral Research, 2002-current
10. NICE Guideline Development Group, 2003-current
11. MRC representative, Specialist Training Authority of the Medical Royal Colleges, 2003-2007
12. Chairman Elect, National Osteoporosis Society of Great Britain, 2003-2007
13. Member Physiological Sciences and Clinical Sciences Board, Medical Research Council 2006 to current
14. Vice-Chair, MRC Population Health Sciences Research Network 2005 to current
15. Member BHF Chairs and Programmes Grants Committee, 2003 to current
16. President, Bone Research Society of Great Britian, 2008-2010
17. Chair, Committee of Scientific Advisers, International Osteoporosis Foundation, 2007 to current

Professor Cooper's PA is Gill Strange.

cc@mrc.soton.ac.uk

Related Publications: 2013  Alfred T;Ben-Shlomo Y;Cooper R;Hardy R;Cooper C;Deary IJ et al. Genetic markers of bone and joint health and physical capability in older adults: the HALCyon programme. Bone 2013; 52:278-285.  Baylis D;Bartlett DB;Syddall HE;Ntani G;Gale CR;Cooper C;Lord JM;Sayer AA. Immune-endocrine biomarkers as predictors of frailty and mortality: a 10-year longitudinal study in community-dwelling older people. Age (Dordr ) 2013; 35:963-971.  Collings PJ;Brage S;Ridgway CL;Harvey NC;Godfrey KM;Inskip HM;Cooper C;Wareham NJ;Ekelund U. Physical activity intensity, sedentary time, and body composition in preschoolers. Am J Clin Nutr 2013; 97:1020-1028.  Cooper C;Adachi JD;Bardin T;Berenbaum F;Flamion B;Jonsson H et al. How to define responders in osteoarthritis. Curr Med Res Opin 2013; 29:719-729.  den HM;Luan J;Langenberg C;Cooper C;Sayer AA;Jameson K et al. Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples. Int J Obes (Lond) 2013; 37:191-196.  Dennison EM;Dhanwal DK;Shaheen SO;Azagra R;Reading I;Jameson KA;Sayer AA;Cooper C. Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study. Arch Osteoporos 2013; 8:115-.  Dhanwal DK;Siwach R;Dixit V;Mithal A;Jameson K;Cooper C. Incidence of hip fracture in Rohtak district, North India. Arch Osteoporos 2013; 8:135-.  Edwards MH;Jameson KA;Denison H;Harvey NC;Sayer AA;Dennison EM;Cooper C. The importance of fall history in fracture risk assessment (letter). Bone 2013; 53:598-.  Edwards MH;Jameson K;Denison H;Harvey NC;Sayer AA;Dennison EM;Cooper C. Clinical risk factors, bone density and fall history in the prediction of incident fracture among men and women. Bone 2013; 52:541-547.  Freemantle N;Cooper C;Diez-Perez A;Gitlin M;Radcliffe H;Shepherd S;Roux C. Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis. Osteoporos Int 2013; 24:209-217.  Gardner MP;Lightman S;Sayer AA;Cooper C;Cooper R;Deeg D et al. Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: An individual participant meta-analysis. Psychoneuroendocrinology 2013; 38:40-49.  Gregson CL;Sayers A;Lazar V;Steel S;Dennison EM;Cooper C;Smith GD;Rittweger J;Tobias JH. The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: Findings from a pQCT case-control study. Bone 2013; 52:380-388.  Hardy R;Cooper R;Aihie SA;Ben-Shlomo Y;Cooper C;Deary IJ et al. Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme. PLoS One 2013; 8:e56483-.  Horikoshi M;Yaghootkar H;Mook-Kanamori DO;Sovio U;Taal HR;Hennig BJ et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet 2013; 45(1):76-82.  Ioannidis G;Flahive J;Pickard L;Papaioannou A;Chapurlat RD;Saag KG et al. Non-hip, non-spine fractures drive healthcare utilization following a fracture: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int 2013; 24:59-67.  Javaid MK;Cooper C. Commentary: Opportunities to prevent fracture are being missed. British Medical Journal 2013; 346:f278-.  Judge A;Arden NK;Batra RN;Thomas G;Beard D;Javaid MK;Cooper C;Murray D. The association of patient characteristics and surgical variables on symptoms of pain and function over 5 years following primary hip-replacement surgery: a prospective cohort study. BMJ Open 2013; 3:-.  Kaufman JM;Reginster JY;Boonen S;Brandi ML;Cooper C;Dere W et al. Treatment of osteoporosis in men. Bone 2013; 53:134-144.  Litwic A;Edwards MH;Dennison EM;Cooper C. Epidemiology and burden of osteoarthritis. Br Med Bull 2013; 105:185-199.  Mithal A;Bonjour JP;Boonen S;Burckhardt P;Degens H;El Hajj FG et al. Impact of nutrition on muscle mass, strength, and performance in older adults. Osteoporos Int 2013; 24:1555-1566.  Moon RJ;Harvey NC;Robinson SM;Ntani G;Davies JH;Inskip HM;Godfrey KM;Dennison EM;Calder PC;Cooper C. Maternal plasma polyunsaturated fatty acid status in late pregnancy is associated with offspring body composition in childhood. J Clin Endocrinol Metab 2013; 98:299-307.  Patel HP;Syddall HE;Jameson K;Robinson S;Denison H;Roberts HC;Edwards M;Dennison E;Cooper C;Aihie SA. Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS). Age and Ageing 2013; 42:378-384.  Peters MJ;Broer L;Willemen HL;Eiriksdottir G;Hocking LJ;Holliday KL et al. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis 2013; 72:427-436.  Pike KC;Inskip HM;Robinson SM;Cooper C;Godfrey KM;Roberts G;Lucas JS. The relationship between maternal adiposity and infant weight gain, and childhood wheeze and atopy. Thorax 2013; 68:372-379.  Pouwels S;de BA;Javaid MK;Hilton-Jones D;Verschuuren J;Cooper C;Leufkens HG;de VF. Fracture rate in patients with myasthenia gravis: the general practice research database. Osteoporos Int 2013; 24:467-476.  Reginster JY;Badurski J;Bellamy N;Bensen W;Chapurlat R;Chevalier X;Christiansen C;Genant H;Navarro F;Nasonov E;Sambrook PN;Spector TD;Cooper C. Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial. Ann Rheum Dis 2013; 72:179-186.  Rizzoli R;Boonen S;Brandi ML;Bruyere O;Cooper C;Kanis JA;Kaufman JM;Ringe JD;Weryha G;Reginster JY. Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin 2013; 29:305-313.  Roberts HC;Pilgrim AL;Elia M;Jackson AA;Cooper C;Sayer AA;Robinson SM. Southampton mealtime assistance study: design and methods. BMC Geriatr 2013; 13:5-.  Robinson S;Ntani G;Simmonds S;Syddall H;Dennison E;Sayer AA;Barker D;Cooper C. Type of milk feeding in infancy and health behaviours in adult life: findings from the Hertfordshire Cohort Study. Br J Nutr 2013; 109:1114-1122.  Sayer AA;Robinson SM;Patel HP;Shavlakadze T;Cooper C;Grounds MD. New horizons in the pathogenesis, diagnosis and management of sarcopenia (editorial). Age and Ageing 2013; 42:145-150.  Svedbom A;Alvares L;Cooper C;Marsh D;Strom O. Balloon kyphoplasty compared to vertebroplasty and nonsurgical management in patients hospitalised with acute osteoporotic vertebral compression fracture: a UK cost-effectiveness analysis. Osteoporos Int 2013; 24:355-367.  Tom SE;Adachi JD;Anderson FA;Boonen S;Chapurlat RD;Compston JE et al. Frailty and fracture, disability, and falls: a multiple country study from the global longitudinal study of osteoporosis in women. J Am Geriatr Soc 2013; 61:327-334.  Vestergaard P;Prieto-Alhambra D;Javaid MK;Cooper C. Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose. Osteoporos Int 2013; 24:671-680.  Vimaleswaran KS;Berry DJ;Lu C;Tikkanen E;Pilz S;Hiraki LT et al. Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLoS Med 2013; 10:e1001383-.  Wahl DA;Cooper C;Ebeling PR;Eggersdorfer M;Hilger J;Hoffmann K;Josse R;Kanis JA;Mithal A;Pierroz DD;Stenmark J;Stocklin E;Dawson-Hughes B. A global representation of vitamin D status in healthy populations: reply to comment by Saadi (letter). Arch Osteoporos 2013; 8:122-.  Worsley P;Warner M;Mottram S;Gadola S;Veeger HE;Hermens H;Morrissey D;Little P;Cooper C;Carr A;Stokes M. Motor control retraining exercises for shoulder impingement: effects on function, muscle activation, and biomechanics in young adults. J Shoulder Elbow Surg 2013; 22:e11-e19. 2012  Alfred T;Ben-Shlomo Y;Cooper R;Hardy R;Cooper C;Deary IJ et al. A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme. PLoS One 2012; 7:e29883-.  Avenell A;MacLennan GS;Jenkinson DJ;McPherson GC;McDonald AM;Pant PR et al. Long-Term Follow-Up for Mortality and Cancer in a Randomized Placebo-Controlled Trial of Vitamin D3 and/or Calcium (RECORD Trial). J Clin Endocrinol Metab 2012; 97:614-622.  Bartlett DB;Firth CM;Phillips AC;Moss P;Baylis D;Syddall H;Sayer AA;Cooper C;Lord JM. The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection. Aging Cell 2012; 11:912-915.  Bazelier MT;van Staa TP;Uitdehaag BM;Cooper C;Leufkens HG;Vestergaard P;Bentzen J;de VF. A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis. Neurology 2012; 79:922-928.  Bazelier MT;van Staa TP;Uitdehaag BM;Cooper C;Leufkens HG;Vestergaard P;Herings RM;de VF. Risk of fractures in patients with multiple sclerosis: a population-based cohort study. Neurology 2012; 78:1967-1973.  Bazelier MT;Gallagher AM;van Staa TP;Cooper C;Leufkens HG;Vestergaard P;de VF. Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?. Pharmacoepidemiol Drug Saf 2012; 21:507-514.  Bazelier MT;Vestergaard P;Gallagher AM;van Staa TP;Cooper C;Leufkens HG;de VF. Risk of fracture with thiazolidinediones: disease or drugs?. Calcif Tissue Int 2012; 90:450-457.  Black C;Ntani G;Kenny R;Tinati T;Jarman M;Lawrence W;Barker M;Inskip H;Cooper C;Moon G;Baird J. Variety and quality of healthy foods differ according to neighbourhood deprivation. Health Place 2012; 18:1292-1299.  Blunden CH;Inskip HM;Robinson SM;Cooper C;Godfrey KM;Kendrick TR. Postpartum depressive symptoms: the B-vitamin link. Ment Health Fam Med 2012; 9:5-13.  Cawston H;Maravic M;Fardellone P;Gauthier A;Kanis JA;Compston J;Borgstrom F;Cooper C;McCloskey E. Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: estimations from a disease model. Arch Osteoporos 2012; 7:237-246.  Cole ZA;Harvey NC;Kim M;Ntani G;Robinson SM;Inskip HM;Godfrey KM;Cooper C;Dennison EM. Increased fat mass is associated with increased bone size but reduced volumetric density in pre pubertal children. Bone 2012; 50:562-567.  Cooper C;Reginster JY;Chapurlat R;Christiansen C;Genant H;Bellamy N;Bensen W;Navarro F;Badurski J;Nasonov E;Chevalier X;Sambrook PN. Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial. Curr Med Res Opin 2012; 28:231-239.  Cooper C;Harvey NC. Osteoporosis risk assessment (editorial). British Medical Journal 2012; 344:e4191-.  Cooper C;Dere W;Evans W;Kanis JA;Rizzoli R;Sayer AA et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int 2012; 23:1839-1848.  Cooper C;Reginster JY;Cortet B;Diaz-Curiel M;Lorenc RS;Kanis JA;Rizzoli R. Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Curr Med Res Opin 2012; 28:475-491.  Cooper C;Frank J;Leyland A;Hardy R;Lawlor DA;Wareham NJ;Dezateux C;Inskip H. Using cohort studies in lifecourse epidemiology. Public Health 2012; 126:190-192.  Craig P;Cooper C;Gunnell D;Haw S;Lawson K;Macintyre S;Ogilvie D;Petticrew M;Reeves B;Sutton M;Thompson S. Using natural experiments to evaluate population health interventions: new Medical Research Council guidance. J Epidemiol Community Health 2012; 66:1182-1186.  Crozier SR;Harvey NC;Inskip HM;Godfrey KM;Cooper C;Robinson SM. Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women's Survey. Am J Clin Nutr 2012; 96:57-63.  Culliford DJ;Maskell J;Kiran A;Judge A;Javaid MK;Cooper C;Arden NK. The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database. Osteoarthritis Cartilage 2012; 20:519-524.  Dastani Z;Hivert MF;Timpson N;Perry JR;Yuan X;Scott RA et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012; 8:e1002607-.  Denison HJ;Jameson KA;Syddall HE;Dennison EM;Cooper C;Sayer AA;Robinson SM. Patterns of dietary supplement use among older men and women in the UK: findings from the Hertfordshire Cohort Study. J Nutr Health Aging 2012; 16:307-311.  Denison HJ;Simmonds SJ;Syddall HE;Robinson SM;Dennison EM;Cooper C;Sayer AA. The Hertfordshire Cohort Study: from historical to high-tech studies of musculoskeletal ageing in men and women entering their ninth decade. Int J Epidemiol 2012; 41:386-389.  Dennison EM;Compston JE;Flahive J;Siris ES;Gehlbach SH;Adachi JD et al. Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW). Bone 2012; 50:1288-1293.  Diez-Perez A;Adachi JD;Agnusdei D;Bilezikian JP;Compston JE;Cummings SR et al. Treatment failure in osteoporosis. Osteoporos Int 2012; 23:2769-2774.  Dodds R;Macdonald-Wallis C;Kapasi T;Sayer AA;Robinson S;Godfrey K;Cooper C;Harvey N;Inskip H. Grip strength at 4 years in relation to birth weight. Journal of Developmental Origins of Health and Disease 2012; 3(02):111-115.  Dodds R;Denison HJ;Ntani G;Cooper R;Cooper C;Sayer AA;Baird J. Birth weight and muscle strength: a systematic review and meta-analysis. J Nutr Health Aging 2012; 16:609-615.  Drake AJ;McPherson RC;Godfrey KM;Cooper C;Lillycrop KA;Hanson MA;Meehan RR;Seckl JR;Reynolds RM. An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clin Endocrinol (Oxf) 2012; 77:808-815.  Druet C;Stettler N;Sharp S;Simmons RK;Cooper C;Davey SG;Ekelund U;Levy-Marchal C;Jarvelin MR;Kuh D;Ong KK. Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis. Paediatr Perinat Epidemiol 2012; 26:19-26.  Edwards MH;Cooper C. Bone: the growing cost of fractures in Ireland. Nat Rev Endocrinol 2012; 8:512-513.  Estrada K;Styrkarsdottir U;Evangelou E;Hsu YH;Duncan EL;Ntzani EE et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012; 44:491-501.  Eyre S;Bowes J;Diogo D;Lee A;Barton A;Martin P et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet 2012; 44:1336-1340.  Fisher BA;Plant D;Lundberg K;Charles P;Barton A;Venables PJ;including Cooper C;including Dennison EM. Heterogeneity of Anticitrullinated Peptide Antibodies and Response to Anti-Tumor Necrosis Factor Agents in Rheumatoid Arthritis. J Rheumatol 2012; 39:929-932.  Fox CS;Liu Y;White CC;Feitosa M;Smith AV;Heard-Costa N et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet 2012; 8:e1002695-.  Gale CR;Dennison EM;Edwards M;Sayer AA;Cooper C. Symptoms of anxiety or depression and risk of fracture in older people: the Hertfordshire Cohort Study. Arch Osteoporos 2012; 7:59-65.  Gale CR;Deary IJ;Cooper C;Batty GD. Intelligence in childhood and chronic widespread pain in middle age: The National Child Development Survey. Pain 2012; 153:2339-2344.  Gale CR;Syddall HE;Bergman H;Brunner EJ;Cooper C;Sayer AA. Close relationships and risk of frailty: the hertfordshire cohort study. J Am Geriatr Soc 2012; 60:390-392.  Gauthier A;Kanis JA;Jiang Y;Dreinhofer K;Martin M;Compston J;Borgstrom F;Cooper C;McCloskey E. Burden of postmenopausal osteoporosis in Germany: estimations from a disease model. Arch Osteoporos 2012; 7:209-218.  Gehlbach S;Saag KG;Adachi JD;Hooven FH;Flahive J;Boonen S et al. Previous fractures at multiple sites increase the risk for subsequent fractures: the Global Longitudinal Study of Osteoporosis in Women. J Bone Miner Res 2012; 27:645-653.  Godfrey KM;Haugen G;Kiserud T;Inskip HM;Cooper C;Harvey NC;Crozier SR;Robinson SM;Davies L;Hanson MA. Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development. PLoS One 2012; 7:e41759-.  Guggina P;Flahive J;Hooven FH;Watts NB;Siris ES;Silverman S et al. Characteristics associated with anti-osteoporosis medication use: Data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) USA cohort. Bone 2012; 51:975-980.  Harvey N;Dhanwal D;Robinson S;Kim M;Inskip H;Godfrey K;Dennison E;Calder P;Cooper C. Does maternal long chain polyunsaturated fatty acid status in pregnancy influence the bone health of children? The Southampton Women's Survey. Osteoporos Int 2012; 23:2359-2367.  Harvey NC;Cooper C. Vitamin D: some perspective please (editorial). British Medical Journal 2012; 345:e4695-.  Harvey NC;Cole ZA;Crozier SR;Kim M;Ntani G;Goodfellow L;Robinson SM;Inskip HM;Godfrey KM;Dennison EM;Wareham N;Ekelund U;Cooper C. Physical activity, calcium intake and childhood bone mineral: a population-based cross-sectional study. Osteoporos Int 2012; 23:121-130.  Harvey NC;Javaid K;Bishop N;Kennedy S;Papageorghiou AT;Fraser R;Gandhi SV;Schoenmakers I;Prentice A;Cooper C. MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. The MAVIDOS Study Group. Trials 2012; 13:13-.  Harvey NC;Lillycrop KA;Garratt E;Sheppard A;McLean C;Burdge G et al. Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content. Calcif Tissue Int 2012; 90:120-127.  Harvey NC;Mahon PA;Kim M;Cole ZA;Robinson SM;Javaid K;Inskip HM;Godfrey KM;Dennison EM;Cooper C. Intrauterine growth and postnatal skeletal development: findings from the Southampton Women's Survey. Paediatr Perinat Epidemiol 2012; 26:34-44.  Holroyd C;Harvey N;Dennison E;Cooper C. Epigenetic influences in the developmental origins of osteoporosis. Osteoporos Int 2012; 23:401-410.  Holroyd CR;Harvey NC;Crozier SR;Winder NR;Mahon PA;Ntani G;Godfrey KM;Inskip HM;Cooper C;including Robinson SM;including Dennison EM;including Osmond C;including Fall C. Placental size at 19 weeks predicts offspring bone mass at birth: Findings from the Southampton Women's Survey. Placenta 2012; 33:623-629.  Ikram MA;Fornage M;Smith AV;Seshadri S;Schmidt R;Debette S et al. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet 2012; 44:539-544.  Inskip H;Macdonald-Wallis C;Kapasi T;Robinson S;Godfrey K;Cooper C;Harvey N;Aihie SA. Associations between grip strength of parents and their 4-year-old children: findings from the Southampton Women's Survey. Paediatr Perinat Epidemiol 2012; 26:27-33.  Ioannou C;Javaid MK;Mahon P;Yaqub MK;Harvey NC;Godfrey KM;Noble JA;Cooper C;Papageorghiou AT. The effect of maternal vitamin d concentration on fetal bone. J Clin Endocrinol Metab 2012; 97:E2070-E2077.  Judge A;Javaid MK;Arden NK;Cushnaghan J;Reading I;Croft P;Dieppe PA;Cooper C. Clinical tool to identify patients who are most likely to achieve long-term improvement in physical function after total hip arthroplasty. Arthritis Care Res (Hoboken ) 2012; 64:881-889.  Judge A;Arden NK;Cooper C;Kassim JM;Carr AJ;Field RE;Dieppe PA. Predictors of outcomes of total knee replacement surgery. Rheumatology (Oxford) 2012; 51:1804-1813.  Kanis JA;Oden A;McCloskey EV;Johansson H;Wahl DA;Cooper C. A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 2012; 23:2239-2256.  Kanis JA;Reginster JY;Kaufman JM;Ringe JD;Adachi JD;Hiligsmann M;Rizzoli R;Cooper C. A reappraisal of generic bisphosphonates in osteoporosis. Osteoporos Int 2012; 23:213-221.  Kohler JA;Moon RJ;Sands R;Doherty LJ;Taylor PA;Cooper C;Dennison EM;Davies JH. Selective reduction in trabecular volumetric bone mineral density during treatment for childhood acute lymphoblastic leukemia. Bone 2012; 51:765-770.  Lalmohamed A;de VF;Bazelier MT;Cooper A;van Staa TP;Cooper C;Harvey NC. Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study. British Medical Journal 2012; 345:e5085-.  Lalmohamed A;Vestergaard P;Cooper C;de BA;Leufkens HG;van Staa TP;de VF. Timing of stroke in patients undergoing total hip replacement and matched controls: a nationwide cohort study. Stroke 2012; 43:3225-3229.  Lawrence W;Keyte J;Tinati T;Haslam C;Baird J;Margetts B;Swift J;Cooper C;Barker M. A mixed-methods investigation to explore how women living in disadvantaged areas might be supported to improve their diets. J Health Psychol 2012; 17:785-798.  Lekamwasam S;Adachi JD;Agnusdei D;Bilezikian J;Boonen S;Borgstrom F et al. A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. Osteoporos Int 2012; 23:2257-2276.  Lekamwasam S;Adachi JD;Agnusdei D;Bilezikian J;Boonen S;Borgstrom F et al. An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis. Arch Osteoporos 2012; 7:25-30.  Lewis RM;Cleal JK;Ntani G;Crozier SR;Mahon PA;Robinson SM;Harvey NC;Cooper C;Inskip HM;Godfrey KM;Hanson MA;John RM. Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass. Bone 2012; 50:337-342.  Leyland KM;Hart DJ;Javaid MK;Judge A;Kiran A;Soni A;Goulston LM;Cooper C;Spector TD;Arden NK. The natural history of radiographic knee osteoarthritis: A fourteen-year population-based cohort study. Arthritis Rheum 2012; 64:2243-2251.  Litwic A;Edwards M;Cooper C;Dennison E. Geographic differences in fractures among women. Womens Health (Lond Engl ) 2012; 8:673-684.  O'Tierney PF;Lewis RM;McWeeney SK;Hanson MA;Inskip HM;Morgan TK;Barker DJ;Bagby G;Cooper C;Godfrey KM;Thornburg KL. Immune response gene profiles in the term placenta depend upon maternal muscle mass. Reprod Sci 2012; 19:1041-1056.  Palmer KT;Harris EC;Linaker C;Barker M;Lawrence W;Cooper C;Coggon D. Effectiveness of community- and workplace-based interventions to manage musculoskeletal-related sickness absence and job loss: a systematic review. Rheumatology (Oxford) 2012; 51:230-242.  Palmer KT;Harris EC;Linaker C;Cooper C;Coggon D. Optimising case definitions of upper limb disorder for aetiological research and prevention: a review. Occup Environ Med 2012; 69:71-78.  Palmer KT;Harris EC;Linaker C;Ntani G;Cooper C;Coggon D. 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The risk of fracture in patients with multiple sclerosis: The UK general practice research database. J Bone Miner Res 2011; 26:2271-2279.  Birnie K;Cooper R;Martin RM;Kuh D;Sayer AA;Alvarado BE et al. Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS One 2011; 6:e15564-.  Blank RD;including Cooper C. Official Positions for FRAX(R) clinical regarding prior fractures from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R). J Clin Densitom 2011; 14:205-211.  Blumsohn A;Marin F;Nickelsen T;Brixen K;Sigurdsson G;Gonzalez dl;Boonen S;Liu-Leage S;Barker C;Eastell R;including Cooper C. Early changes in biochemical markers of bone turnover and their relationship with bone mineral density changes after 24 months of treatment with teriparatide. 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Official Positions for FRAX((R)) clinical regarding glucocorticoids: the impact of the use of glucocorticoids on the estimate by FRAX((R)) of the 10 year risk of fracture from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX((R)). J Clin Densitom 2011; 14:212-219.  Lewiecki EM;Compston JE;Miller PD;Adachi JD;Adams JE;Leslie WD;Kanis JA;including Cooper C. FRAX((R)) Bone Mineral Density Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference. J Clin Densitom 2011; 14:223-225.  Lewiecki EM;Compston JE;Miller PD;Adachi JD;Adams JE;Leslie WD et al. Official Positions for FRAX(R) Bone Mineral Density and FRAX(R) simplification from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R). J Clin Densitom 2011; 14:226-236.  Linaker C;Harris EC;Cooper C;Coggon D;Palmer KT. The burden of sickness absence from musculoskeletal causes in Great Britain. Occup Med (Lond) 2011; 61:458-464.  Marsh D;Akesson K;Beaton DE;Bogoch ER;Boonen S;Brandi ML;McLellan AR;Mitchell PJ;Sale JE;Wahl DA;including Cooper C. Coordinator-based systems for secondary prevention in fragility fracture patients. Osteoporos Int 2011; 22:2051-2065.  Martin H;Aihie SA;Jameson K;Syddall H;Dennison EM;Cooper C;Robinson S. Does diet influence physical performance in community-dwelling older people? Findings from the Hertfordshire Cohort Study. Age and Ageing 2011; 40:181-186.  Masud T;Binkley N;Boonen S;Hannan MT;including Cooper C. Official Positions for FRAX(R) clinical regarding falls and frailty: can falls and frailty be used in FRAX(R)? From Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R). J Clin Densitom 2011; 14:194-204.  McCloskey EV;Binkley N;including Cooper C. FRAX((R)) Clinical Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference. J Clin Densitom 2011; 14:181-183.  McCloskey EV;Vasikaran S;Cooper C. Official Positions for FRAX(R) clinical regarding biochemical markers from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(R). J Clin Densitom 2011; 14:220-222.  Mishra GD;Gale CR;Sayer AA;Cooper C;Dennison EM;Whalley LJ;Craig L;Kuh D;Deary IJ. How useful are the SF-36 sub-scales in older people? Mokken scaling of data from the HALCyon programme. Qual Life Res 2011; 20:1005-1010.  Muraki S;Dennison E;Jameson K;Boucher BJ;Akune T;Yoshimura N;Judge A;Arden NK;Javaid K;Cooper C. Association of vitamin D status with knee pain and radiographic knee osteoarthritis. 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Calcif Tissue Int 2011; 89:91-104.  Rizzoli R;Akesson K;Bouxsein M;Kanis JA;Napoli N;Papapoulos S;Reginster JY;Cooper C. Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporos Int 2011; 22:373-390.  Roberts HC;Denison HJ;Martin HJ;Patel HP;Syddall H;Cooper C;Sayer AA. A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age and Ageing 2011; 40:423-429.  Roux C;Cooper C;ez-Perez A;Martinez L;Ortolani S;Gitlin M;Moller G;Shepherd S;Freemantle N. Prevalence of osteoporosis and fractures among women prescribed osteoporosis medication in five European countries: the POSSIBLE EU((R)) study. Osteoporos Int 2011; 22:1227-1236.  Sambrook PN;Flahive J;Hooven FH;Boonen S;Chapurlat R;Lindsay R et al. Predicting fractures in an international cohort using risk factor algorithms without BMD. J Bone Miner Res 2011; 26:2770-2777.  Shaheen SO;Jameson KA;Robinson SM;Boucher BJ;Syddall HE;Aihie SA;Cooper C;Holloway JW;Dennison EM. Relationship of vitamin D status to adult lung function and COPD. Thorax 2011; 66:692-698.  Siris ES;Gehlbach S;Adachi JD;Boonen S;Chapurlat RD;Compston JE et al. Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int 2011; 22:27-35.  Soler AM;Wain LV;Repapi E;Obeidat M;Sayers I;Burton PR et al. Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function. Am J Respir Crit Care Med 2011; 184:786-795.  Soler AM;Loth DW;Wain LV;Gharib SA;Obeidat M;Tang W et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011; 43:1082-1090.  Speliotes EK;Yerges-Armstrong LM;Wu J;Hernaez R;Kim LJ;Palmer CD et al. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet 2011; 7:e1001324-.  Strawbridge RJ;Dupuis J;Prokopenko I;Barker A;Ahlqvist E;Rybin D et al. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. Diabetes 2011; 60:2624-2634.  Valdes AM;Evangelou E;Kerkhof HJ;Tamm A;Doherty SA;Kisand K et al. The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance (letter). Ann Rheum Dis 2011; 70:873-875.  Valdes AM;De WG;Doherty SA;Lories RJ;Vaughn FL;Laslett LL et al. The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. Ann Rheum Dis 2011; 70:1556-1561.  Valdes AM;Styrkarsdottir U;Doherty M;Morris DL;Mangino M;Tamm A et al. Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations. PLoS One 2011; 6:e23371-.  Valdes AM;Arden NK;Vaughn FL;Doherty SA;Leaverton PE;Zhang W et al. Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain. Arthritis Care Res (Hoboken ) 2011; 63:440-444.  Varanasi SS;Tuck SP;Mastana SS;Dennison E;Cooper C;Vila J;Francis RM;Datta HK. Lack of association of bone morphogenetic protein 2 gene haplotypes with bone mineral density, bone loss, or risk of fractures in men. J Osteoporos 2011; 2011:243465-.  Vasikaran S;Cooper C;Eastell R;Griesmacher A;Morris HA;Trenti T;Kanis JA. International Osteoporosis Foundation and International Federation of Clinical Chemistry and Laboratory Medicine Position on bone marker standards in osteoporosis. Clin Chem Lab Med 2011; 49:1271-1274.  Vasikaran S;Eastell R;Bruyere O;Foldes AJ;Garnero P;Griesmacher A;McClung M;Morris HA;Silverman S;Trenti T;Wahl DA;Cooper C;Kanis JA. Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards. Osteoporos Int 2011; 22:391-420.  Vasikaran SD;Cooper C;Kanis JA. Recommendations for bone marker standards in osteoporosis: what, why and where to now? (editorial). Ann Clin Biochem 2011; 48:91-92.  Vasikaran SD;Morris HA;Cooper C;Kanis JA. Standardising biochemical assessment of bone turnover in osteoporosis (editorial). Clin Biochem 2011; 44:1033-1034.  Wahl DA;Cooper C;Boonen S. Clinicians need to treat underlying osteoporosis (letter). British Medical Journal 2011; 343:d5040-.  Williams FM;Popham M;Hart DJ;de SE;Bierma-Zeinstra S;Hofman A;Uitterlinden AG;Arden NK;Cooper C;Spector TD;Valdes AM;van MJ. GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women. Arthritis Rheum 2011; 63:708-712.  Zhu H;Shyh-Chang N;Segre AV;Shinoda G;Shah SP;Einhorn WS et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 2011; 147:81-94. 2010  Abrahamsen B;Masud T;Avenell A;Anderson F;Meyer HE;Cooper C et al. Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe. British Medical Journal 2010; 340:b5463-.  Adachi JD;Adami S;Gehlbach S;Anderson FA;Boonen S;Chapurlat RD et al. Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women. Mayo Clin Proc 2010; 85:806-813.  Adams J;Mullee M;Burridge J;Hammond A;Cooper C. Responsiveness of self-report and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis. Arthritis Care Res (Hoboken ) 2010; 62:274-278.  Ashfield TA;Syddall HE;Martin HJ;Dennison EM;Cooper C;Aihie SA. Grip strength and cardiovascular drug use in older people: findings from the Hertfordshire Cohort Study. Age and Ageing 2010; 39:185-191.  Breart G;Cooper C;Meyer O;Speirs C;Deltour N;Reginster JY. Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database. Osteoporos Int 2010; 21:1181-1187.  Cooper C. Osteoporosis research thrives: IOF WCO-ECCEO10. Expert Rev Pharmacoecon Outcomes Res 2010; 10:367-370.  Cooper C. Osteoporosis: disease severity and consequent fracture management. Osteoporos Int 2010; 21 Suppl 2:S425-S429.  Cooper C;Steinbuch M;Stevenson R;Miday R;Watts NB. The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK. Osteoporos Int 2010; 21:569-577.  Cooper R;Kuh D;Hardy R;including Cooper C;including Aihie Sayer A;including Gale CR;including Syddall HE. Objectively measured physical capability levels and mortality: systematic review and meta-analysis. British Medical Journal 2010; 341:c4467-.  Crozier SR;Inskip HM;Godfrey KM;Cooper C;Harvey NC;Cole ZA;Robinson SM. Weight gain in pregnancy and childhood body composition: findings from the Southampton Women's Survey. Am J Clin Nutr 2010; 91:1745-1751.  Crozier SR;Inskip HM;Barker ME;Lawrence WT;Cooper C;Robinson SM. Development of a 20-item food frequency questionnaire to assess a 'prudent' dietary pattern among young women in Southampton. Eur J Clin Nutr 2010; 64:99-104.  De Lucia RE;Sleigh A;Finucane FM;Brage S;Stolk RP;Cooper C;Sharp SJ;Wareham NJ;Ong KK. Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women. Obesity (Silver Spring) 2010; 18:625-631.  Dennison EM;Jameson KA;Syddall HE;Martin HJ;Cushnaghan J;Aihie SA;Cooper C. Bone health and deterioration in quality of life among participants from the Hertfordshire cohort study. Osteoporos Int 2010; 21:1817-1824.  Dennison EM;Cooper C;Cole ZA. Early development and osteoporosis and bone health.. Journal of Developmental Origins of Health and Disease 2010; 1:142-149.  Dhanwal DK;Cooper C;Dennison EM. Geographic variation in osteoporotic hip fracture incidence: the growing importance of asian influences in coming decades. J Osteoporos 2010; 2010:757102-.  Dhanwal DK;Kochupillai N;Gupta N;Cooper C;Dennison EM. Hypovitaminosis D and bone mineral metabolism and bone density in hyperthyroidism. J Clin Densitom 2010; 13:462-466.  Dupuis J;Langenberg C;Prokopenko I;Saxena R;Soranzo N;Jackson AU et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010; 42:105-116.  Earl S;Cole ZA;Holroyd C;Cooper C;Harvey NC. Session 2: Other diseases: Dietary management of osteoporosis throughout the life course. Proc Nutr Soc 2010; 69:25-33.  Finucane FM;Sharp SJ;Purslow LR;Horton K;Horton J;Savage DB et al. The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial. Diabetologia 2010; 53:624-631.  Freemantle N;Cooper C;Roux C;ez-Perez A;Guillemin F;Jonsson B et al. Baseline observations from the POSSIBLE EU(R) study: characteristics of postmenopausal women receiving bone loss medications. Arch Osteoporos 2010; 5:61-72.  Gale CR;Allerhand M;Sayer AA;Cooper C;Dennison EM;Starr JM;Ben-Shlomo Y;Gallacher JE;Kuh D;Deary IJ. The structure of the Hospital Anxiety and Depression Scale in four cohorts of community-based, healthy older people: the HALCyon program. Int Psychogeriatr 2010; 22:559-571.  Gale CR;Marriott LD;Martyn CN;Limond J;Inskip HM;Godfrey KM;Law CM;Cooper C;West C;Robinson SM. Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood. Arch Dis Child 2010; 95:174-179.  Goodfellow LR;Earl S;Cooper C;Harvey NC. Maternal diet, behaviour and offspring skeletal health. International Journal of Environmental Research and Public Health 2010; 7(4):1760-1772.  Harvey N;Dennison E;Cooper C. Osteoporosis: impact on health and economics. Nat Rev Rheumatol 2010; 6:99-105.  Harvey NC;Mahon PA;Robinson SM;Nisbet CE;Javaid MK;Crozier SR;Inskip HM;Godfrey KM;Arden NK;Dennison EM;Cooper C. Different indices of fetal growth predict bone size and volumetric density at 4 years of age. J Bone Miner Res 2010; 25:920-927.  Harvey NC;Javaid MK;Arden NK;Poole JR;Crozier SR;Robinson SM;Inskip HM;Godfrey KM;Dennison EM;Cooper C. Maternal predictors of neonatal bone size and geometry: the Southampton Women's Survey. Journal of Developmental Origins of Health and Disease 2010; 1:35-41.  Hassan B;Maxwell JR;Hyrich KL;Barton A;Worthington J;Isaacs JD;Morgan AW;Wilson AG;including Cooper C;including Arden NK;including Dennison EM. Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford) 2010; 49:43-47.  Holroyd CR;Davies JH;Taylor P;Jameson K;Rivett C;Cooper C;Dennison EM. Reduced cortical bone density with normal trabecular bone density in girls with Turner syndrome. Osteoporos Int 2010; 21:2093-2099.  Ingelsson E;Langenberg C;Hivert MF;Prokopenko I;Lyssenko V;Dupuis J et al. Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes 2010; 59:1266-1275.  Judge A;Cooper C;Williams S;Dreinhoefer K;Dieppe P. Patient-reported outcomes one year after primary hip replacement in a European Collaborative Cohort. Arthritis Care Res (Hoboken ) 2010; 62:480-488.  Langston AL;Campbell MK;Fraser WD;MacLennan GS;Selby PL;Ralston SH;including Cooper C;including Harvey NC;including Cushnaghan J. Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone. J Bone Miner Res 2010; 25:20-31.  Lewiecki EM;Cooper C;Thompson E;Hartl F;Mehta D;Papapoulos SE. Ibandronate does not increase risk of atrial fibrillation in analysis of pivotal clinical trials. Int J Clin Pract 2010; 64:821-826.  Lewis RM;Greenwood SL;Cleal JK;Crozier SR;Verrall L;Inskip HM;Cameron IT;Cooper C;Sibley CP;Hanson MA;Godfrey KM. Maternal muscle mass may influence system A activity in human placenta. Placenta 2010; 31:418-422.  Lips P;Jameson K;Bianchi ML;Goemaere S;Boonen S;Reeve J;Stepan J;Johnell O;van Schoor NM;Dennison E;Kanis JA;Cooper C. Validation of the IOF quality of life questionnaire for patients with wrist fracture. Osteoporos Int 2010; 21:61-70.  Lyritis G;Marin F;Barker C;Pfeifer M;Farrerons J;Brixen K;del PJ;Keen R;Nickelsen TN;including Cooper C. Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS. Curr Med Res Opin 2010; 26:1799-1807.  Mahon P;Harvey N;Crozier S;Inskip H;Robinson S;Arden N;Swaminathan R;Cooper C;Godfrey K. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res 2010; 25:14-19.  McCloskey E;Compston J;Cooper C. The US FRAX filter: avoiding confusion or hindering progress? (letter). Osteoporos Int 2010; 21:885-.  Nettleton JA;McKeown NM;Kanoni S;Lemaitre RN;Hivert MF;Ngwa J et al. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care 2010; 33:2684-2691.  Patel HP;Syddall HE;Martin HJ;Stewart CE;Cooper C;Sayer AA. Hertfordshire sarcopenia study: design and methods. BMC Geriatr 2010; 10:43-.  Pazianas M;Cooper C;Ebetino FH;Russell RG. Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis. Ther Clin Risk Manag 2010; 6:325-343.  Pouwels S;Lalmohamed A;Leufkens HG;de Boer A;Cooper C;van Staa T;de Vries F. Risk of fracture and bone mineral density in stroke response (letter). Stroke 2010; 41(1):E60-.  Pouwels S;Lalmohamed A;van ST;Cooper C;Souverein P;Leufkens HG;Rejnmark L;de BA;Vestergaard P;de VF. Use of organic nitrates and the risk of hip fracture: a population-based case-control study. J Clin Endocrinol Metab 2010; 95:1924-1931.  Price AJ;Longino D;Rees J;Rout R;Pandit H;Javaid K;Arden N;Cooper C;Carr AJ;Dodd CA;Murray DW;Beard DJ. Are pain and function better measures of outcome than revision rates after TKR in the younger patient?. Knee 2010; 17:196-199.  Repapi E;Sayers I;Wain LV;Burton PR;Johnson T;Obeidat M et al. Genome-wide association study identifies five loci associated with lung function. Nat Genet 2010; 42:36-44.  Saxena R;Hivert MF;Langenberg C;Tanaka T;Pankow JS;Vollenweider P et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010; 42:142-148.  Sayer AA;Stewart C;Patel H;Cooper C. The developmental origins of sarcopenia: from epidemiological evidence to underlying mechanisms. Journal of Developmental Origins of Health and Disease 2010; 1(3):150-157.  Shaheen SO;Jameson KA;Syddall HE;Aihie SA;Dennison EM;Cooper C;Robinson SM. The relationship of dietary patterns with adult lung function and COPD. Eur Respir J 2010; 36:277-284.  Strom O;Leonard C;Marsh D;Cooper C. Cost-effectiveness of balloon kyphoplasty in patients with symptomatic vertebral compression fractures in a UK setting. Osteoporos Int 2010; 21:1599-1608.  Syddall H;Roberts HC;Evandrou M;Cooper C;Bergman H;Aihie SA. Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study. Age and Ageing 2010; 39:197-203.  Syddall HE;Simmonds SJ;Martin HJ;Watson C;Dennison EM;Cooper C;Sayer AA. Cohort profile: The Hertfordshire Ageing Study (HAS). Int J Epidemiol 2010; 39:36-43.  Szopa M;Meirhaeghe A;Luan J;Moreno LA;Gonzalez-Gross M;Vidal-Puig A;Cooper C;Hagen R;Amouyel P;Wareham NJ;Loos RJ. No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits. Am J Clin Nutr 2010; 92:252-257.  Valdes AM;McWilliams D;Arden NK;Doherty SA;Wheeler M;Muir KR;Zhang W;Cooper C;Maciewicz RA;Doherty M. Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. Arthritis Rheum 2010; 62:2688-2695.  Valdes AM;Spector TD;Tamm A;Kisand K;Doherty SA;Dennison EM et al. Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. Arthritis Rheum 2010; 62:2347-2352.  Valdes AM;Arden NK;Tamm A;Kisand K;Doherty S;Pola E et al. A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis. Osteoarthritis Cartilage 2010; 18:699-704.  Wang TJ;Zhang F;Richards JB;Kestenbaum B;van Meurs JB;Berry D et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010; 376:180-188. 2009  Abdin-Mohamed M;Jameson K;Dennison EM;Cooper C;Arden NK. Volumetric bone mineral density of the tibia is not increased in subjects with radiographic knee osteoarthritis. Osteoarthritis Cartilage 2009; 17:174-177.   Abrahamsen B;van ST;Ariely R;Olson M;Cooper C. Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int 2009; 20:1633-1650.  Baird J;Cooper C;Margetts BM;Barker M;Inskip HM. Changing health behaviour of young women from disadvantaged backgrounds: evidence from systematic reviews. Proc Nutr Soc 2009; 68:195-204.  Barker M;Lawrence W;Crozier S;Robinson S;Baird J;Margetts B;Cooper C. Educational attainment, perceived control and the quality of women's diets. Appetite 2009; 52:631-636.  Boonen S;Kay R;Cooper C;Haentjens P;Vanderschueren D;Callewaert F;Milisen K;Ferrari S. Osteoporosis management: a perspective based on bisphosphonate data from randomised clinical trials and observational databases. Int J Clin Pract 2009; 63:1792-1804.  Cole ZA;Gale CR;Javaid MK;Robinson SM;Law C;Boucher BJ;Crozier SR;Godfrey KM;Dennison EM;Cooper C. Maternal dietary patterns during pregnancy and childhood bone mass: a longitudinal study. J Bone Miner Res 2009; 24:663-668.  Cole ZA;Dennison EM;Cooper C. The impact of methods for estimating bone health and the global burden of bone disease. Salud Publica Mex 2009; 51 Suppl 1:S38-S45.  Compston J;Cooper A;Cooper C;Francis R;Kanis JA;Marsh D;McCloskey EV;Reid DM;Selby P;Wilkins M. Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK. Maturitas 2009; 62:105-108.  Cooper C;Westlake S;Harvey N;Dennison E. Developmental origins of osteoporotic fracture. Adv Exp Med Biol 2009; 639:217-236.  Cooper C;Rizzoli R;Reginster JY. The International Osteoporosis Foundation: history, objectives and achievements. Osteoporos Int 2009; 20 Suppl 3:S241-S242.  Cooper C;Harvey N;Cole Z;Hanson M;Dennison E. Developmental origins of osteoporosis: the role of maternal nutrition. Adv Exp Med Biol 2009; 646:31-39.  Cranney A;Wells GA;Yetisir E;Adami S;Cooper C;Delmas PD;Miller PD;Papapoulos S;Reginster JY;Sambrook PN;Silverman S;Siris E;Adachi JD. Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data. Osteoporos Int 2009; 20:291-297.   Crozier SR;Robinson SM;Borland SE;Godfrey KM;Cooper C;Inskip HM. Do women change their health behaviours in pregnancy? Findings from the Southampton Women's Survey. Paediatr Perinat Epidemiol 2009; 23:446-453.  Crozier SR;Robinson SM;Godfrey KM;Cooper C;Inskip HM. Women's dietary patterns change little from before to during pregnancy. J Nutr 2009; 139:1956-1963.  Cushnaghan J;Bennett J;Reading I;Croft P;Byng P;Cox K;Dieppe P;Coggon D;Cooper C. Long-term outcome following total knee arthroplasty: a controlled longitudinal study. Ann Rheum Dis 2009; 68:642-647.  de VF;Cooper AL;Cockle SM;van Staa TP;Cooper C. Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates. Osteoporos Int 2009; 20:1989-1998.  Dennison EM;Syddall HE;Jameson KA;Sayer AA;Gaunt TR;Rodriguez S;Day IN;Cooper C;Lips MA. A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study. J Rheumatol 2009; 36:1520-1526.  Finucane FM;Horton J;Purslow LR;Savage DB;Brage S;Besson H et al. Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial. BMC Endocr Disord 2009; 9:15-.  Gale CR;Batty GD;Cooper C;Deary IJ. Psychomotor coordination and intelligence in childhood and health in adulthood--testing the system integrity hypothesis. Psychosom Med 2009; 71:675-681.  Gale CR;Martyn CN;Marriott LD;Limond J;Crozier S;Inskip HM;Godfrey KM;Law CM;Cooper C;Robinson SM. Dietary patterns in infancy and cognitive and neuropsychological function in childhood. J Child Psychol Psychiatry 2009; 50:816-823.  Harvey NC;Robinson SM;Crozier SR;Marriott LD;Gale CR;Cole ZA;Inskip HM;Godfrey KM;Cooper C. Breast-feeding and adherence to infant feeding guidelines do not influence bone mass at age 4 years. Br J Nutr 2009; 102:915-920.  Holt RI;Phillips DI;Jameson KA;Cooper C;Dennison EM;Peveler RC. The relationship between depression and diabetes mellitus: findings from the Hertfordshire Cohort Study. Diabet Med 2009; 26:641-648.  Hooven FH;Adachi JD;Adami S;Boonen S;Compston J;Cooper C et al. The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design. Osteoporos Int 2009; 20:1107-1116.  Inskip HM;Crozier SR;Godfrey KM;Borland SE;Cooper C;Robinson SM. Women's compliance with nutrition and lifestyle recommendations before pregnancy: general population cohort study. British Medical Journal 2009; 338:b481-.   Lam SC;Allen R;Pearson G;Cooper C. Parametric characterization of spinal motions in osteoporotic vertebral fracture at level T12 with fluoroscopy. Med Eng Phys 2009; 31:346-355.  Lawrence W;Skinner TC;Haslam C;Robinson S;Inskip H;Barker D;Cooper C;Jackson A;Barker M. Why women of lower educational attainment struggle to make healthier food choices: the importance of psychological and social factors. Psychology and Health 2009; 24(9):1003-1020.  Lindgren CM;Heid IM;Randall JC;Lamina C;Steinthorsdottir V;Qi L et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009; 5:e1000508-.  Liu B;Balkwill A;Cooper C;Roddam A;Brown A;Beral V. Reproductive history, hormonal factors and the incidence of hip and knee replacement for osteoarthritis in middle-aged women. Ann Rheum Dis 2009; 68:1165-1170.  Mahon PA;Cooper C;Crozier SR;Godfrey KM. The use of 3D ultrasound to investigate fetal bone development. Norwegian Journal of Epidemiology 2009; 19:45-52.  Martin HJ;Syddall HE;Dennison EM;Cooper C;Sayer AA. Physical performance and physical activity in older people: are developmental influences important?. Gerontology 2009; 55:186-193.  McMinn AM;van Sluijs EM;Harvey NC;Cooper C;Inskip HM;Godfrey KM;Griffin SJ. Validation of a maternal questionnaire on correlates of physical activity in preschool children. Int J Behav Nutr Phys Act 2009; 6:81-.  Pouwels S;Lalmohamed A;Leufkens B;de BA;Cooper C;van ST;de VF. Risk of hip/femur fracture after stroke: a population-based case-control study. Stroke 2009; 40:3281-3285.  Pouwels S;van Staa TP;Egberts AC;Leufkens HG;Cooper C;de VF. Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study. Osteoporos Int 2009; 20:1499-1506.  Reid DM;Devogelaer JP;Saag K;Roux C;Lau CS;Reginster JY;Papanastasiou P;Ferreira A;Hartl F;Fashola T;Mesenbrink P;Sambrook PN;including Cooper C. Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial. Lancet 2009; 373:1253-1263.  Robinson S;Syddall H;Jameson K;Batelaan S;Martin H;Dennison EM;Cooper C;Sayer AA. Current patterns of diet in community-dwelling older men and women: results from the Hertfordshire Cohort Study. Age and Ageing 2009; 38:594-599.  Robinson SM;Marriott LD;Crozier SR;Harvey NC;Gale CR;Inskip HM;Baird J;Law CM;Godfrey KM;Cooper C. Variations in infant feeding practice are associated with body composition in childhood: a prospective cohort study. J Clin Endocrinol Metab 2009; 94:2799-2805.  Syddall H;Evandrou M;Cooper C;Sayer AA. Social inequalities in grip strength, physical function, and falls among community dwelling older men and women: findings from the Hertfordshire Cohort Study. J Aging Health 2009; 21:913-939.  Syddall HE;Martin HJ;Harwood RH;Cooper C;Aihie SA. The SF-36: a Simple, Effective Measure of Mobility-Disability for Epidemiological Studies. J Nutr Health Aging 2009; 13:57-62.  van den Brand MW;Samson MM;Pouwels S;van Staa TP;Thio B;Cooper C;Leufkens HG;Egberts AC;Verhaar HJ;de VF. Use of anti-depressants and the risk of fracture of the hip or femur. Osteoporos Int 2009; 20:1705-1713.  Willer CJ;Speliotes EK;Loos RJ;Li S;Lindgren CM;Heid IM et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41:25-34.  Williams EL;Harvey N;Dennison E;Edwards C;Cooper C. Maternal nutrition and bone health in the offspring. Int J Clin Rheumatol 2009; 4:133-145.  Winsloe C;Earl S;Dennison EM;Cooper C;Harvey NC. Early life factors in the pathogenesis of osteoporosis. Curr Osteoporos Rep 2009; 7:140-144. 2008  Adams J;Burridge J;Mullee M;Hammond A;Cooper C. The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial. Rheumatology (Oxford) 2008; 47:1548-1553.  Ashwell M;Stone E;Mathers J;Barnes S;Compston J;Francis RM et al. Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy?. Br J Nutr 2008; 99:198-205.   Baird J;Poole J;Robinson S;Marriott L;Godfrey K;Cooper C;Inskip H;Law C. Milk feeding and dietary patterns predict weight and fat gains in infancy. Paediatr Perinat Epidemiol 2008; 22:575-586.  Barker M;Lawrence WT;Skinner TC;Haslam CO;Robinson SM;Inskip HM;Margetts BM;Jackson AA;Barker DJ;Cooper C. Constraints on food choices of women in the UK with lower educational attainment. Public Health Nutr 2008; 11:1229-1237.  Batty GD;Smith GD;Cooper C;Gale CR. Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33,261 individuals from the Hertfordshire studies. 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The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis. Arthritis Rheum 2007; 57:1151-1157.   Edwards CJ;Syddall H;Goswami R;Goswami P;Dennison EM;Arden NK;Cooper C. The autoantibody rheumatoid factor may be an independent risk factor for ischaemic heart disease in men. Heart 2007; 93:1263-1267.   Gale CR;Martyn CN;Cooper C;Sayer AA. Grip strength, body composition, and mortality. Int J Epidemiol 2007; 36:228-235.   Gale CR;Javaid MK;Robinson SM;Law CM;Godfrey KM;Cooper C. Maternal size in pregnancy and body composition in children. J Clin Endocrinol Metab 2007; 92:3904-3911.   Harvey NC;Poole JR;Javaid MK;Dennison EM;Robinson S;Inskip HM;Godfrey KM;Cooper C;Sayer AA. Parental determinants of neonatal body composition. J Clin Endocrinol Metab 2007; 92:523-526.  Inskip HM;Godfrey KM;Martin HJ;Simmonds SJ;Cooper C;Aihie Sayer A. 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Relationships between SF-36 health profile and bone mineral density: the Hertfordshire Cohort Study. Osteoporos Int 2006; 17:1435-1442.  Edwards CJ;Syddall H;Goswami R;Goswami P;Dennison EM;Cooper C. Infections in infancy and the presence of antinuclear antibodies in adult life. Lupus 2006; 15:213-217.  Edwards CJ;Goswami R;Goswami P;Syddall H;Dennison EM;Arden NK;Cooper C. Growth and infectious exposure during infancy and the risk of rheumatoid factor in adult life. Ann Rheum Dis 2006; 65:401-404.  Edwards CJ;Cooper C. Early environmental factors and rheumatoid arthritis. Clin Exp Immunol 2006; 143:1-5.  Fawcett KA;Wareham NJ;Luan J;Syddall H;Cooper C;O'rahilly S;Day IN;Sandhu MS;Barroso I. PARL Leu262Val is not associated with fasting insulin levels in UK populations. Diabetologia 2006; 49:2649-2652.  Ganpule A;Yajnik CS;Fall CH;Rao S;Fisher DJ;Kanade A;Cooper C;Naik S;Joshi N;Lubree H;Deshpande V;Joglekar C. Bone Mass in Indian Children--Relationships to Maternal Nutritional Status and Diet during Pregnancy: the Pune Maternal Nutrition Study. J Clin Endocrinol Metab 2006; 91:2994-3001.  Hashimoto J;Ohno I;Nakatsuka K;Yoshimura N;Takata S;Zamma M et al. Prevalence and clinical features of Paget's disease of bone in Japan. J Bone Miner Metab 2006; 24:186-190.  Inskip HM;Godfrey KM;Robinson SM;Law CM;Barker DJ;Cooper C. Cohort profile: The Southampton Women's Survey. International Journal of Epidemiology 2006; 35:42-48.  Jakob F;Marin F;Martin-Mola E;Torgerson D;Fardellone P;Adami S;Thalassinos NC;Sykes D;Melo-Gomes J;Chinn C;Nicholson T;Cooper C. Characterization of patients with an inadequate clinical outcome from osteoporosis therapy: the Observational Study of Severe Osteoporosis (OSSO). QJM 2006; 99:531-543.  Javaid MK;Lekamwasam S;Clark J;Dennison EM;Syddall HE;Loveridge N;Reeve J;Beck TJ;Cooper C. Infant growth influences proximal femoral geometry in adulthood. 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Age and Ageing 2006; 35:82-84.  Kuh D;Hardy R;Butterworth S;Okell L;Richards M;Wadsworth M;Cooper C;Sayer AA. Developmental origins of midlife physical performance: evidence from a British birth cohort. American Journal of Epidemiology 2006; 164:110-121.  Kuh D;Hardy R;Butterworth S;Okell L;Wadsworth M;Cooper C;Aihie Sayer A. Developmental origins of midlife grip strength: findings from a birth cohort study. J Gerontol A Biol Sci Med Sci 2006; 61:702-706.  Lundkvist J;Johnell O;Cooper C;Sykes D. Economic evaluation of parathyroid hormone (PTH) in the treatment of osteoporosis in postmenopausal women. Osteoporos Int 2006; 17:201-211.  Martin HJ;Yule V;Syddall HE;Dennison EM;Cooper C;Aihie Sayer A. Is hand-held dynamometry useful for the measurement of quadriceps strength in older people? A comparison with the gold standard biodex dynamometry. Gerontology 2006; 52:154-159.  Oreffo R;Cooper C;Mason C;Clements M. Mesenchymal stem cells - lineage, plasticity and skeletal therapeutic potential. Stem Cells Reviews 2006; 1:169-178.  Palmer KT;Cooper C. Work-related disorders of the upper limb. Arthritis Research Campaign: Topical Reviews 2006; 10:1-7.  Poor G;Donath J;Fornet B;Cooper C. Epidemiology of Paget's Disease in Europe: The Prevalence Is Decreasing. J Bone Miner Res 2006; 21:1545-1549.  Reginster JY;Adami S;Lakatos P;Greenwald M;Stepan JJ;Silverman SL et al. Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2 year results from the MOBILE study. Ann Rheum Dis 2006; 65:654-661.  Reginster JY;Felsenberg D;Cooper C;Stakkestad JA;Miller PD;Kendler DL et al. A new concept for bisphosphonate therapy: a rationale for the development of monthly oral dosing of ibandronate. Osteoporos Int 2006; 17:159-166.  Reid DM;Mackay I;Wilkinson S;Miller C;Schuette DG;Compston J et al. Cross-calibration of dual-energy X-ray densitometers for a large, multi-center genetic study of osteoporosis. Osteoporos Int 2006; 17:125-132.  Robinson SM;Batelaan SF;Syddall HE;Sayer AA;Dennison EM;Martin HJ;Barker DJ;Cooper C. Combined effects of dietary fat and birth weight on serum cholesterol concentrations: the Hertfordshire Cohort Study. Am J Clin Nutr 2006; 84:237-244.  Rodriguez S;Huang S;Chen XH;Gaunt TR;Syddall HE;Gilg JA;Miller GJ;Cooper C;Cook DG;Whincup PH;Day IN. A study of TH01 and IGF2-INS-TH haplotypes in relation to smoking initiation in three independent surveys. Pharmacogenet Genomics 2006; 16:15-23.  Rodriguez S;Gaunt TR;Dennison E;Chen XH;Syddall HE;Phillips DI;Cooper C;Day IN. Replication of IGF2-INS-TH(*)5 haplotype effect on obesity in older men and study of related phenotypes. Eur J Hum Genet 2006; 14:109-116.  Sambrook P;Cooper C. Seminar on osteoporosis. Osteoporosis: trends in epidemiology, pathogenesis and treatment. Lancet 2006; 367:2010-2018.  Sayer AA;Syddall HE;Martin HJ;Dennison EM;Anderson FH;Cooper C. Falls, sarcopenia, and growth in early life: findings from the hertfordshire cohort study. American Journal of Epidemiology 2006; 164:665-671.  Sayer AA;Syddall HE;Martin HJ;Dennison EM;Roberts HC;Cooper C. Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study. Age and Ageing 2006; 35:409-415.  Staa TP;Geusens P;Bijlsma JW;Leufkens HG;Cooper C. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006; 54:3104-3112.  van Schoor NM;Knol DL;Glas CA;Ostelo RW;Leplege A;Cooper C;Johnell O;Lips P. Development of the Qualeffo-31, an osteoporosis-specific quality-of-life questionnaire. Osteoporos Int 2006; 17:543-551.  van Staa TP;Geusens P;Kanis JA;Leufkens HG;Gehlbach S;Cooper C. A simple clinical score for estimating the long-term risk of fracture in post-menopausal women. QJM 2006; 99:673-682.  Walker-Bone K;Reading I;Coggon D;Cooper C;Palmer KT. Risk factors for specific upper limb disorders as compared with non-specific upper limb pain: assessing the utility of a structured examination schedule. Occup Med (Lond) 2006; 56:243-250.  Yang XB;Webb D;Blaker J;Boccaccini AR;Maquet V;Cooper C;Oreffo RO. Evaluation of human bone marrow stromal cell growth on biodegradable polymer/bioglass composites. Biochem Biophys Res Commun 2006; 342:1098-1107.  Yoshimura N;Kinoshita H;Hori N;Nishioka T;Ryujin M;Mantani Y et al. Risk factors for knee osteoarthritis in Japanese men: a case-control study. Mod Rheumatol 2006; 16:24-29. 2005  Abdollahi MR;Gaunt TR;Syddall HE;Cooper C;Phillips DI;Ye S;Day IN. Angiotensin II type I receptor gene polymorphism: anthropometric and metabolic syndrome traits. J Med Genet 2005; 42:396-401.  Adams J;Burridge J;Mullee M;Hammond A;Cooper C. Self-reported hand functional ability measured by the DASH in individuals with early rheumatoid arthritis. Br J Hand Therapy 2005; 10:21-24.  Alharbi KK;Aldahmesh MA;Spanakis E;Haddad L;Whittall RA;Chen XH et al. Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population. Genome Res 2005; 15:967-977.  Arden NK;Price C;Reading I;Stubbing J;Hazelgrove J;Dunne C;Michel M;Rogers P;Cooper C. A multicentre randomized controlled trial of epidural corticosteroid injections for sciatica: the WEST study. Rheumatology (Oxford) 2005; 44:1399-1406.  Arden NK;Syddall HE;Javaid MK;Dennison EM;Swaminathan R;Fall C;Cooper C. Early life influences on serum 1,25 (OH) vitamin D. Paediatr Perinat Epidemiol 2005; 19:36-42.   Birrell F;Arden NK;Conaghan PG;Cooper C;Dieppe P;Doherty M. Is it time for more rheumatologists to embrace osteoarthritis?. Rheumatology (Oxford) 2005; 44:829-830.   Cooper C;Javaid K;Westlake S;Harvey N;Dennison E. Developmental origins of osteoporotic fracture: the role of maternal vitamin d insufficiency. Journal of Nutrition 2005; 135:2728S-2734S.  Cooper C. Epidemiology of osteoporotic fracture: looking to the future. Rheumatology (Oxford) 2005; 44 Suppl 4:iv36-iv40.  Cooper MS;Syddall HE;Fall CH;Wood PJ;Stewart PM;Cooper C;Dennison EM. Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study. Clin Endocrinol (Oxf) 2005; 62:692-697.  de Vries F;van Staa TP;Bracke MS;Cooper C;Leufkens HG;Lammers JW. Severity of obstructive airway disease and risk of osteoporotic fracture. Eur Respir J 2005; 25:879-884.  Delmas PD;Rizzoli R;Cooper C;Reginster JY. Treatment of patients with postmenopausal osteoporosis is worthwhile. The position of the International Osteoporosis Foundation. Osteoporos Int 2005; 16:1-5.   Dennison E;Syddall H;Fall C;Brandi ML;Cooper C. Evidence of sexual dimorphism in relationships between estrogen receptor polymorphisms and bone mass: the hertfordshire study. J Rheumatol 2005; 32:2400-2404.  Dennison E;Cole Z;Cooper C. Diagnosis and epidemiology of osteoporosis. Curr Opin Rheumatol 2005; 17:456-461.  Dennison EM;Syddall HE;Sayer AA;Gilbody HJ;Cooper C. Birth Weight and Weight at 1 Year Are Independent Determinants of Bone Mass in the Seventh Decade: The Hertfordshire Cohort Study. Pediatr Res 2005; 57:582-586.   Edwards CJ;Arden NK;Fisher D;Saperia JC;Reading I;van Staa TP;Cooper C. The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database. Rheumatology (Oxford) 2005; 44:1394-1398.  Grant AM;Avenell A;Campbell MK;McDonald AM;MacLennan GS;McPherson GC et al. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 2005; 365:1621-1628.  Harvey N;Cooper C. Physiotherapy for neck and back pain. British Medical Journal 2005; 330:53-54.  Harvey NC;Dennison E;Cooper C. The epidemiology of osteoporotic fractures. Osteoporosis Review 2005; 13:1-5.  including Cooper C. PASSCLAIM (Process for the Assessment of Scientific Support for Claims on Foods). A European Commission Concerted Action Project Co-ordinated by ILSI Europe. Eur J Clin Nutr 2005; 44 Suppl 1:-.  Javaid MK;Crozier SR;Harvey NC;Taylor P;Inskip HM;Godfrey KM;Cooper C. Maternal and seasonal predictors of change in calcaneal quantitative ultrasound during pregnancy. J Clin Endocrinol Metab 2005; 90:5182-5187.  Javaid MK;Godfrey KM;Taylor P;Robinson SM;Crozier SR;Dennison EM;Robinson JS;Breier BR;Arden NK;Cooper C. Umbilical Cord Leptin Predicts Neonatal Bone Mass. Calcif Tissue Int 2005; 76:341-347.  Jordan KM;Syddall H;Dennison EM;Cooper C;Arden NK. Birthweight, vitamin D receptor gene polymorphism, and risk of lumbar spine osteoarthritis. J Rheumatol 2005; 32:678-683.  Mahon PA;Godfrey KM;Crozier SR;Petley GW;Inskip HM;Cooper C. Ultrasound assessment of fetal musculo-skeletal development. BJOG: an international journal of obstetrics and gynaecology 2005; 112:1446-1453.  Melton LJ;Chrischilles EA;Cooper C;Lane AW;Riggs BL. How many women have osteoporosis? JBMR Anniversary Classic. JBMR, Volume 7, Number 9, 1992. J Bone Miner Res 2005; 20:886-892.  Miller PD;McClung MR;Macovei L;Stakkestad JA;Luckey M;Bonvoisin B et al. Monthly Oral Ibandronate Therapy in Postmenopausal Osteoporosis: 1-Year Results From the MOBILE Study. J Bone Miner Res 2005; 20:1315-1322.  Palmer KT;Milne P;Poole J;Cooper C;Coggon D. Employment characteristics and job loss in patients awaiting surgery on the hip or knee. Occup Environ Med 2005; 62:54-57.  Patel MB;Arden NK;Masterson LM;Phillips DI;Swaminathan R;Syddall HE;Byrne CD;Wood PJ;Cooper C;Holt RI. Investigating the role of the growth hormone-insulin-like growth factor (GH-IGF) axis as a determinant of male bone mineral density (BMD). Bone 2005; 37:833-841.  Phillips DI;Goulden P;Syddall HE;Aihie Sayer A;Dennison EM;Martin H;Cooper C. Fetal and infant growth and glucose tolerance in the hertfordshire cohort study: a study of men and women born between 1931 and 1939. Diabetes 2005; 54 Suppl 2:S145-S150.  Ralston SH;Galwey N;Mackay I;Albagha OM;Cardon L;Compston JE et al. Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study. Hum Mol Genet 2005; 14:943-951.   Reading I;Walker-Bone K;Palmer KT;Cooper C;Coggon D. Utility of restricted neck movement as a diagnostic criterion in case definition for neck disorders. Scand J Work Environ Health 2005; 31:387-393.  Reynolds RM;Dennison EM;Walker BR;Syddall HE;Wood PJ;Andrew R;Phillips DI;Cooper C. Cortisol Secretion and Rate of Bone Loss in a Population-Based Cohort of Elderly Men and Women. Calcif Tissue Int 2005; 77:134-138.  Sayer AA;Cooper C. Fetal programming of body composition and musculoskeletal development. Early Hum Dev 2005; 81:735-744.  Sayer AA;Dennison EM;Syddall HE;Gilbody HJ;Phillips DI;Cooper C. Type 2 Diabetes, Muscle Strength, and Impaired Physical Function: The tip of the iceberg?. Diabetes Care 2005; 28:2541-2542.  Smedley J;Inskip H;Buckle P;Cooper C;Coggon D. Epidemiological differences between back pain of sudden and gradual onset. J Rheumatol 2005; 32:528-532.  Syddall HE;Sayer AA;Simmonds SJ;Osmond C;Cox V;Dennison EM;Barker DJ;Cooper C. Birth Weight, Infant Weight Gain, and Cause-specific Mortality: The Hertfordshire Cohort Study. Am J Epidemiol 2005; 161:1074-1080.  Syddall HE;Sayer AA;Dennison EM;Martin HJ;Barker DJ;Cooper C. Cohort Profile: The Hertfordshire Cohort Study. International Journal of Epidemiology 2005; 34:1234-1242.  Tobias JH;Steer CD;Emmett PM;Tonkin RJ;Cooper C;Ness AR. Bone mass in childhood is related to maternal diet in pregnancy. Osteoporos Int 2005; 16:1731-1741.  van Staa TP;Leufkens HG;Abenhaim L;Zhang B;Cooper C. Use of oral corticosteroids and risk of fractures. J Bone Miner Res 2005; 20:1487-1494.  van Staa TP;Geusens P;Pols HA;De Laet C;Leufkens HG;Cooper C. A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids. QJM 2005; 98:191-198.   Walker-Bone K;Cooper C. Hard work never hurt anyone: or did it? A review of occupational associations with soft tissue musculoskeletal disorders of the neck and upper limb. Ann Rheum Dis 2005; 64:1391-1396. 2004  Adams J;Burridge J;Mullee M;Hammond A;Cooper C. Correlation between upper limb functional ability and structural hand impairment in an early rheumatoid population. Clin Rehabil 2004; 18:405-413.  Avenell A;Grant AM;McGee M;McPherson G;Campbell MK;McGee MA;RECORD trial management group (including Cooper C. The effects of an open design on trial participant recruitment, compliance and retention--a randomized controlled trial comparison with a blinded, placebo-controlled design. Clin Trials 2004; 1:490-498.  Cockerill W;Lunt M;Silman AJ;Cooper C;Lips P;Bhalla A et al. Health-related quality of life and radiographic vertebral fracture. Osteoporosis International 2004; 15:113-119.  Cooper C;Jordan KM. Topical NSAIDs in osteoarthritis. British Medical Journal 2004; 329:304-305.  Cooper C;Dennison EM;Leufkens HG;Bishop N;van Staa TP. Epidemiology of childhood fractures in Britain: a study using the general practice research database. Journal of Bone and Mineral Research 2004; 19:1976-1981.  Davidson P;Milne R;Chase D;Cooper C. Growth hormone replacement in adults and bone mineral density: a systematic review and meta-analysis. Clinical Endocrinology 2004; 60:92-98.  Day IN;Chen XH;Gaunt TR;King TH;Voropanov A;Ye S et al. Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster. J Clin Endocrinol Metab 2004; 89:5569-5576.  Delmas PD;Li Z;Cooper C. Relationship between changes in bone mineral density and fracture risk reduction with antiresorptive drugs: some issues with meta-analyses. Journal of Bone and Mineral Research 2004; 19:330-337.  Dennison EM;Syddall HE;Fall CH;Javaid MK;Arden NK;Phillips DI;Cooper C. Plasma leptin concentration and change in bone density among elderly men and women: the Hertfordshire Cohort Study. Calcified Tissue International 2004; 74:401-406.  Dennison EM;Syddall HE;Aihie Sayer A;Craighead S;Phillips DI;Cooper C. Type 2 diabetes mellitus is associated with increased axial bone density in men and women from the Hertfordshire Cohort Study: evidence for an indirect effect of insulin resistance?. Diabetologia 2004; 47:1963-1968.  Dennison EM;Syddall HE;Rodriguez S;Voropanov A;Day IN;Cooper C. Polymorphism in the growth hormone gene, weight in infancy, and adult bone mass. J Clin Endocrinol Metab 2004; 89:4898-4903.  Eekhoff ME;van der Klift M;Kroon HM;Cooper C;Hofman A;Pols HA. Paget's disease of bone in the Netherlands: a population-based radiological and biochemical survey - the Rotterdam study. Journal of Bone and Mineral Research 2004; 19:566-570.  Haentjens P;Johnell O;Kanis JA;Bouillon R;Cooper C;Lamraski G;Vanderschueren D;Kaufman JM;Boonen S. Evidence from data searches and life-table analyses for gender-related differences in absolute risk of hip fracture after Colles' or spine fracture: Colles' fracture as an early and sensitive marker of skeletal fragility in white men. Journal of Bone and Mineral Research 2004; 19:1933-1944.  Harvey N;Cooper C. Epidemiology of vertebral fractures. Advances in Osteoporotic Fracture Management 2004; 3:78-83.  Harvey N;Dennison E;Cooper C. Early life determinants of osteoporotic fracture. Osteoporosis Review 2004; 12:1-4.  Harvey N;Cooper C. The developmental origins of osteoporotic fracture. J Br Menopause Soc 2004; 10:14-29.  Javaid MK;Godfrey KM;Taylor P;Shore SR;Breier B;Arden NK;Cooper C. Umbilical venous IGF-1 concentration, neonatal bone mass, and body composition. Journal of Bone and Mineral Research 2004; 19:56-63.  Javaid MK;Arden NK;Cooper C. Association of birth weight with osteoporosis and osteoarthritis in adult twins. Rheumatology (Oxford) 2004; 43:401-.  Jordan KM;Sawyer S;Coakley P;Smith HE;Cooper C;Arden NK. The use of conventional and complementary treatments for knee osteoarthritis in the community. Rheumatology (Oxford) 2004; 43:381-384.  Koay MA;Woon PY;Zhang Y;Miles LJ;Duncan EL;Ralston SH et al. Influence of LRP5 polymorphisms on normal variation in BMD. Journal of Bone and Mineral Research 2004; 19:1619-1627.  Mahon PA;Petley GW;Cooper C;Godfrey KM;Crozier SR. Three-dimensional ultrasound and the volumetric assessment of fetal long bones.. Ultrasound 2004; 12 (4):232-233.  Mehta G;Taylor P;Petley GW;Dennison E;Cooper C;Walker-Bone K. Bone mineral status in immigrant Indo-Asian women. QJM: monthly journal of the Association of Physicians 2004; 97:95-99.  Nurmi-Lawton JA;Baxter-Jones AD;Mirwald RL;Bishop JA;Taylor P;Cooper C;New SA. Evidence of sustained skeletal benefits from impact-loading exercise in young females: a 3-year longitudinal study. Journal of Bone and Mineral Research 2004; 19:177-182.  O'Neill TW;Cockerill W;Matthis C;Raspe HH;Lunt M;Cooper C et al. Back pain, disability, and radiographic vertebral fracture in European women: a prospective study. Osteoporosis International 2004; 15:760-765.  Puffer S;Torgerson DJ;Sykes D;Brown P;Cooper C. Health care costs of women with symptomatic vertebral fractures. Bone 2004; 35:383-386.  Sayer AA;Syddall HE;Dennison EM;Gilbody HJ;Duggleby SL;Cooper C;Barker DJ;Phillips DI. Birth weight, weight at 1 year of age, and body composition in older men: findings from the Hertfordshire Cohort Study. Am J Clin Nutr 2004; 80:199-203.  Sayer AA;Syddall HE;Gilbody HJ;Dennison EM;Cooper C. Does sarcopenia originate in early life? Findings from the Hertfordshire cohort study. J Gerontol A Biol Sci Med Sci 2004; 59:M930-M934.  Souverein PC;Berard A;van Staa TP;Cooper C;Egberts AC;Leufkens HG;Walker BR. Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case-control study. Heart 2004; 90:859-865.  Tobias JH;Cooper C. PTH/PTHrP activity and the programming of skeletal development in utero. Journal of Bone and Mineral Research 2004; 19:177-182.  Torgerson DJ;Sykes D;Puffer S;Brown P;Cooper C. Pharmaceutical treatment of symptomatic vertebral fractures in primary care. Annals of the Rheumatic Diseases 2004; 63:853-856.  van Staa TP;Bishop N;Leufkens HG;Cooper C. Are inhaled corticosteroids associated with an increased risk of fracture in children?. Osteoporosis International 2004; 15:785-791.  Walker-Bone K;Palmer KT;Reading I;Coggon D;Cooper C. Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis and Rheumatism 2004; 51:642-651.  Walker-Bone K;Reading I;Coggon D;Cooper C;Palmer KT. The anatomical pattern and determinants of pain in the neck and upper limbs: an epidemiologic stgudy. Pain 2004; 109:45-51.  Watts NB;Cooper C;Lindsay R;Eastell R;Manhart MD;Barton IP;van Staa TP;Adachi JD. Relationship between changes in bone mineral density and vertebral fracture risk associated with risedronate: greater increases in bone mineral density do not relate to greater decreases in fracture risk. J Clin Densitom 2004; 7:255-261.  Yoshimura N;Nishioka S;Kinoshita H;Hori N;Nishioka T;Ryujin M;Mantani Y;Miyake M;Coggon D;Cooper C. Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities. J Rheumatol 2004; 31:157-162. 2003  Arden NK;Cooper C. Assessment of the risk of fracture in patients with gastrointestinal disease. Eur J Gastroenterol Hepatol 2003; 15:865-868.  Baker P;Reading I;Cooper C;Coggon D. Knee disorders in the general population and their relation to occupation. Occup Environ Med 2003; 60:794-797.  Birrell F;Silman A;Croft P;Cooper C;Hosie G;Macfarlane G. Syndrome of symptomatic adult acetabular dysplasia (SAAD syndrome). Annals of the Rheumatic Diseases 2003; 62:356-358.  Birrell F;Afzal C;Nahit E;Lunt M;Macfarlane GJ;Cooper C;Croft PR;Hosie G;Silman AJ. Predictors of hip joint replacement in new attenders in primary care with hip pain. Br J Gen Pract 2003; 53:26-30.  Christodoulou C;Cooper C. What is osteoporosis?. Postgraduate Medical Journal 2003; 79:133-138.  Cooper C;Choy E;Arthritis Research Campaign's Clinical Trials Committee. The blossoming on evidence-based clinical rheumatology: the Arthritis Research Campaign's Clinical Trials Collaboration in association with the MRC Clinical Trials Unit, BSR and BOA. Rheumatology (Oxford) 2003; 42:713-715.  Cooper C;Emkey RD;McDonald RH;Hawker G;Bianchi G;Wilson K;Schimmer RC. Efficacy and safety of oral weekly ibandronate in the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab 2003; 88:4609-4615.  Dennison EM;Hindmarsh PC;Kellingray S;Fall CH;Cooper C. Growth hormone predicts bone density in elderly women. Bone 2003; 32:434-440.  Harvey N;Cooper C. Determinants of fracture risk in osteoporosis. Current Rheumatology Reports 2003; 5:75-81.  Harvey N;Javaid K;Cooper C. Osteoporosis: reducing the risk. Arthritis Today 2003; 120:12-14.  Harvey N;Javaid K;Cooper C. Osteoporosis. Arthritis Today 2003; :-.  Lunt M;O'Neill TW;Felsenberg D;Reeve J;Kanis JA;Cooper C;Silman AJ;European Prospective Osteoporosis Study Group. Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS). Bone 2003; 33:505-513.  Mitchell S;Reading I;Walker-Bone K;Palmer K;Cooper C;Coggon D. Pain tolerance in upper limb disorders: findings from a community survey. Occup Environ Med 2003; 60:217-221.  Oreffo RO;Lashbrooke B;Roach HI;Clarke NM;Cooper C. Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring. Bone 2003; 33:100-107.  Palmer KT;Syddall H;Cooper C;Coggon D. Smoking and musculoskeletal disorders: findings from a British national survey. Annals of the Rheumatic Diseases 2003; 62:33-36.  Palmer KT;Griffin MJ;Syddall HE;Pannett B;Cooper C;Coggon D. The relative importance of whole body vibration and occupational lifting as risk factors for low-back pain. Occup Environ Med 2003; 60:715-721.  Poole J;Sayer AA;Cox V;Cooper C;Kuh D;Hardy R;Wadsworth M. Birth weight, osteoarthritis of the hand, and cardiovascular disease in men. Annals of the Rheumatic Diseases 2003; 62:1029-.  Poole J;Aihie Sayer A;Hardy R;Wadsworth M;Kuh D;Cooper C. Patterns of interpahalangeal hand joint involvement of osteoarthritis among men and women: a British cohort study. Arthritis and Rheumatism 2003; 48:3371-3376.  Prentice A;Bonjour JP;Branca F;Cooper C;Flynn A;Garabedian M;Muller D;Pannemans D;Weber P. PASSCLAIM - bone health and osteoporosis. Eur J Clin Nutr 2003; 42 Suppl 1:I28-I49.  Pye SR;O'Neill TW;Lunt M;Kanis JA;Cooper C;Johnell O;Reeve J;Silman AJ;European Prospective Osteoporosis Study Group. Risk factors for Colles' fracture in men and women: results from the European Prospective Osteoporosis Study. Osteoporosis International 2003; 14:213-218.  Reading I;Walker-Bone K;Palmer KT;Cooper C;Coggon D. Anatomic distribution of sensory symptoms in the hand and their relation to neck pain, psychosocial variables, and occupational activities. American Journal of Epidemiology 2003; 157:524-530.  Roach HI;Mehta G;Oreffo RO;Clarke NM;Cooper C. Temporal analysis of rat growth plates: cessation of growth with age despite presence of a physis. J Histochem Cytochem 2003; 51:373-383.  Roach HI;Clarke NM;Langley-Evans S;Cooper C. Catabolic and anabolic phases of osteodystrophy in aged rats. J Bone Miner Metab 2003; 21:299-306.  Roy DK;O'Neill TW;Finn JD;Lunt M;Silman AJ;Felsenberg D et al. Determinants of incident vertebral fracture in men and women: results from the European Prospective Osteoporosis Study (EPOS). Osteoporosis International 2003; 14:19-26.  Sayer AA;Poole J;Cox V;Kuh D;Hardy R;Wadsworth M;Cooper C. Weight from birth to 53 years: a longitudinal study of the influence on clinical hand osteoarthritis. Arthritis and Rheumatism 2003; 48:1030-1033.  Seton M;Choi HK;Hansen MF;Sebaldt RJ;Cooper C. Analysis of environmental factors in familial versus sporadic Paget's disease of bone - the New England Registry for Paget's Disease of Bone. Journal of Bone and Mineral Research 2003; 18:1519-1524.  Smedley J;Trevelyan F;Inskip H;Buckle P;Cooper C;Coggon D. The impact of ergonomic intervention on back pain in nurses. Scandinavian Journal of Work, Environment & Health 2003; 29:117-123.  Smedley J;Inskip H;Trevelyan F;Buckle P;Cooper C;Coggon D. Risk factors for incident neck and shoulder pain in hospital nurses. Occup Environ Med 2003; 60:864-869.  Sorensen OH;Crawford GM;Mulder H;Hosking DJ;Gennari C;Mellstrom D;Pack S;Wenderoth D;Cooper C;Reginster JY. Long-term efficacy of risedronate: a 5 year placebo-controlled clinical experience. Bone 2003; 32:120-126.  Souverein PC;van Staa TP;Egberts AC;de la Rosette JJ;Cooper C;Leufkens HG. Use of alpha blockers and risk of hip/femur fractures. J Int Med 2003; 254:548-554.  Syddall H;Cooper C;Martin F;Briggs R;Aihie Sayer A. Is grip strength a useful single marker of frailty?. Age and Ageing 2003; 32:650-656.  van Staa TP;Laan RF;Barton IP;Cohen S;Reid DM;Cooper C. Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis and Rheumatism 2003; 48:3224-3229.  van Staa TP;Cooper C;Leufkens HG;Lammers JW;Suissa S. The use of inhaled corticosteroids in the United Kingdom and the Netherlands. Respiratory Medicine 2003; 97:578-585.  van Staa TP;Cooper C;Leufkens HG;Bishop N. Children and the risk of fractures caused by oral corticosteroids. Journal of Bone and Mineral Research 2003; 18:913-918.  van Staa TP;Boulton F;Cooper C;Hagenbeek A;Inskip H;Leufkens HG. Neutropenia and agranulocytosis in England and Wales: incidence and risk factors. Am J Hematol 2003; 72:248-254.  van Staa TP;Cooper C;Brusse LS;Leufkens H;Javaid MK;Arden NK. Inflammatory bowel disease and the risk of fracture. Gastroenterology 2003; 125:1591-1597.  van Staa TP;Leufkens HG;Cooper C. Inhaled corticosteroids and hip fracture: disease or drug?. American Journal of Respiratory and Critical Care Medicine 2003; 168:128-.  Walker-Bone K;Reading I;Coggon D;Palmer K;Cooper C. The diagnosis of soft tissue disorders of the upper limb. J Orthopaed Med 2003; 25:97-106.  Walker-Bone KE;Palmer KT;Reading I;Cooper C. Soft tissue rheumatic disorders of the neck and upper limb: prevalence and risk factors. Seminars Arth Rheum 2003; 33:185-203.  Walker-Bone KE;Palmer KT;Reading I;Cooper C. Criteria for assessing non-articular soft tissue rheumatic disorders of the neck and upper limb. Seminars Arth Rheum 2003; 33:168-184.  Zhang B;Ye S;Sayer AA;Hammans SR;Adio S;Hinks LJ;Smythe PJ;Groot D;Cooper C;Day IN. A study of mitochondrial DNA mutations in peripheral lymphocytes in an aging cohort. Biochem Soc Trans 2003; 31:444-446.